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Optical coherence tomography in STEMI with bioresorbable scaffold: possible cause of coronary flow impairment? A sub-study from the Prague 19 trial

Loffi, Marco
Author Loffi, Marco ORCID Cardiology Clinic, Dipartimento di Scienze Cliniche e di Comunità, UO Malattie Cardiovascolari, Fondazione IRCCS, Ospedale Maggiore Policlinico, University of Milan, Via Francesco Sforza 35, 20122, Milan, Italy. loffi.marco@gmail.com
Tousek, Petr
Author Tousek, Petr Cardiocenter, Third Faculty of Medicine, University Hospital Kralovske Vinohrady, Charles University, Prague, Czech Republic
Budesinsky, Tomas
Author Budesinsky, Tomas Cardiocenter, Third Faculty of Medicine, University Hospital Kralovske Vinohrady, Charles University, Prague, Czech Republic
Lisa, Libor
Author Lisa, Libor Cardiocenter, Third Faculty of Medicine, University Hospital Kralovske Vinohrady, Charles University, Prague, Czech Republic
Santangelo, Andrea
Author Santangelo, Andrea Department of Cardiology, University of Palermo, Palermo, Italy
Widimsky, Petr
Author Widimsky, Petr Cardiocenter, Third Faculty of Medicine, University Hospital Kralovske Vinohrady, Charles University, Prague, Czech Republic
Kocka, Viktor
Author Kocka, Viktor Cardiocenter, Third Faculty of Medicine, University Hospital Kralovske Vinohrady, Charles University, Prague, Czech Republic

Heart and vessels. 2018 Nov ; 33 (11) : 1282-1287. [epub] 20180518

Heart Vessels
ISSN 1615-2573 | 0910-8327
Source

Language English Country Japan Media print-electronic

Document type Journal Article, Multicenter Study, Randomized Controlled Trial

Persistent link https://www.medvik.cz/link/pmid29777297

PubMed 29777297
DOI 10.1007/s00380-018-1184-7
PII: 10.1007/s00380-018-1184-7
Knihovny.cz E-resources

Keywords
Bioabsorbable scaffold, Coronary blood flow, Optical coherence tomography, STEMI,
MeSH
Time Factors MeSH
Everolimus pharmacology MeSH
ST Elevation Myocardial Infarction diagnosis physiopathology surgery MeSH
Coronary Angiography MeSH
Percutaneous Coronary Intervention MeSH
Coronary Vessels diagnostic imaging surgery MeSH
Coronary Circulation physiology MeSH
Humans MeSH
Tomography, Optical Coherence methods MeSH
Prospective Studies MeSH
Prosthesis Design MeSH
Regional Blood Flow physiology MeSH
Drug-Eluting Stents MeSH
Tissue Scaffolds * MeSH
Absorbable Implants * MeSH
Treatment Outcome MeSH
Check Tag
Humans MeSH
Male MeSH
Female MeSH
Publication type
Journal Article MeSH
Multicenter Study MeSH
Randomized Controlled Trial MeSH
Names of Substances
Everolimus MeSH

This study assessed the Optical Coherence Tomography (OCT) impact on the coronary flow in ST-elevation myocardial infarction (STEMI) after bioresorbable scaffold implantation. Only few data about OCT use in STEMI are available and coronary flow before and after OCT is not well studied yet. 54 patients with OCT performed at the end of procedure from the Prague 19 trial were selected and coronary flow was evaluated as TIMI frame count (TFC) before and just after OCT. Significant increase in TIMI frame count after OCT [from 9.5 (6.75-12.25) to 11.5 (8-15.25) frames; p = 0.001] and high verapamil administration (18%) was reported. OCT at the end of primary percutaneous coronary intervention with bioresorbable scaffold is a feasible procedure. However, it seems to be associated with flow deterioration.

Cardiocenter 3rd Faculty of Medicine University Hospital Kralovske Vinohrady Charles University Prague Czech Republic

Cardiology Clinic Dipartimento di Scienze Cliniche e di Comunità UO Malattie Cardiovascolari Fondazione IRCCS Ospedale Maggiore Policlinico University of Milan Via Francesco Sforza 35 20122 Milan Italy

Department of Cardiology University of Palermo Palermo Italy

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