Mycobacterium avium complex infection in pigs: A review
Language English Country England, Great Britain Media print-electronic
Document type Journal Article, Review
PubMed
30017080
DOI
10.1016/j.cimid.2018.06.005
PII: S0147-9571(18)30034-1
Knihovny.cz E-resources
- Keywords
- Diagnosis, Immunity, Mycobacterium avium complex, Pathogenesis, Porcine,
- MeSH
- DNA, Bacterial genetics MeSH
- Mycobacterium avium-intracellulare Infection diagnosis epidemiology microbiology veterinary MeSH
- Humans MeSH
- Mycobacterium avium Complex classification genetics immunology isolation & purification MeSH
- Swine Diseases diagnosis epidemiology microbiology MeSH
- Polymerase Chain Reaction methods MeSH
- Swine MeSH
- Interferon-gamma Release Tests methods MeSH
- Tuberculin Test MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
- Geographicals
- Europe epidemiology MeSH
- Names of Substances
- DNA, Bacterial MeSH
Mycobacterial infections in pigs are caused particularly by the Mycobacterium avium complex (MAC) and these infections lead to great economic losses mainly within the countries with high pork meat production. The importance of the MAC infections in humans is rising because of its higher prevalence and also higher mortality rates particularly in advanced countries. In addition, treatment of the MAC infections in humans tends to be complicated because of its increasing resistance to antimicrobial agents. Several studies across Europe have documented the MAC occurrence in the slaughtered pigs - not only in their lymph nodes and tonsils, which are the most frequent, but also in the diaphragmas, other organs and not least in meat. This is why we need both more specific and more sensitive methods for the MAC infection detection. Different PCR assays were established as well as advanced intravital testing by the gamma interferon release test. On the other hand, tuberculin skin test is still one of the cheapest methods of mycobacterial infections detection.
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