Endothelial Progenitor Cells Biology in Diabetes Mellitus and Peripheral Arterial Disease and their Therapeutic Potential

. 2019 Apr ; 15 (2) : 157-165.

Jazyk angličtina Země Spojené státy americké Médium print

Typ dokumentu časopisecké články, práce podpořená grantem, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/pmid30413930
Odkazy

PubMed 30413930
DOI 10.1007/s12015-018-9863-4
PII: 10.1007/s12015-018-9863-4
Knihovny.cz E-zdroje

Endothelial progenitors are a population of cells with the inherent capacity to differentiate into mature endothelial cells and proangiogenic paracrine action. These characteristics have led to extensive studies being performed and tested in the treatment of tissue ischemia. The natural course of diabetes mellitus (DM) results in multiple areas of vascular damage. Thus endothelial progenitor cells'(EPCs) beneficial potential is particularly desirable in diabetic patients. In this review, we summarize contemporary knowledge of EPC biology in DM. It has been shown that EPC functions are considerably impaired by DM. The presence of peripheral arterial disease (PAD) seems to further exacerbate the deficiencies of EPCs. However, studies examining EPC counts in PAD and DM observed disparate results, which can be due to a lack of consensus on precise EPC immunotype used in the different studies. Nevertheless, the results of EPC-based autologous cell therapy (ACT) are promising. In addition, EPCs have been shown to bean independent predictor of cardiovascular risk and diabetic foot ulcer healing.

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Lancet. 2002 Aug 10;360(9331):427-35 PubMed

Circulation. 2002 Nov 26;106(22):2781-6 PubMed

Cardiovasc Surg. 2002 Dec;10(6):570-8 PubMed

Trends Cardiovasc Med. 2003 Jul;13(5):201-6 PubMed

J Am Coll Cardiol. 2003 Dec 17;42(12):2073-80 PubMed

Diabetes. 2004 Dec;53(12):3226-32 PubMed

Int J Biochem Cell Biol. 2005 Apr;37(4):715-9 PubMed

Appl Immunohistochem Mol Morphol. 2005 Sep;13(3):205-20 PubMed

Arterioscler Thromb Vasc Biol. 2006 Feb;26(2):257-66 PubMed

Arterioscler Thromb Vasc Biol. 2006 Sep;26(9):2140-6 PubMed

Arterioscler Thromb Vasc Biol. 2007 Jan;27(1):113-9 PubMed

Circulation. 2006 Dec 12;114(24):2679-84 PubMed

Am Heart J. 2006 Dec;152(6):1051.e1-8 PubMed

Thromb Haemost. 2007 Dec;98(6):1335-42 PubMed

Circulation. 2009 Feb 10;119(5):699-708 PubMed

Biochem Biophys Res Commun. 2009 Apr 3;381(2):192-7 PubMed

Diabet Med. 2009 Feb;26(2):134-41 PubMed

Int J Cardiol. 2010 Sep 3;143(3):368-72 PubMed

Diabetologia. 2009 Aug;52(8):1464-73 PubMed

Cell Transplant. 2009;18(3):371-80 PubMed

Atherosclerosis. 2010 Mar;209(1):10-7 PubMed

Vasc Med. 2010 Aug;15(4):279-85 PubMed

Endocrine. 2010 Oct;38(2):266-75 PubMed

J Vasc Surg. 2011 Feb;53(2):445-53 PubMed

Circ Cardiovasc Interv. 2011 Feb 1;4(1):26-37 PubMed

Diabetes Obes Metab. 2011 May;13(5):439-45 PubMed

Circ Res. 2012 Feb 17;110(4):624-37 PubMed

Exp Diabetes Res. 2012;2012:921685 PubMed

Cardiovasc Diabetol. 2012 Apr 30;11:46 PubMed

Diabetologia. 2012 Sep;55(9):2501-12 PubMed

Cytometry A. 2012 Oct;81(10):856-64 PubMed

Circ Res. 2013 Feb 1;112(3):510-22 PubMed

Arterioscler Thromb Vasc Biol. 2013 Mar;33(3):555-64 PubMed

Diabetes Metab Res Rev. 2013 Jul;29(5):369-76 PubMed

Circ Res. 2013 Apr 26;112(9):1288-302 PubMed

Clin Cancer Res. 2013 Jul 1;19(13):3360-8 PubMed

Clin Chim Acta. 2014 Jan 1;427:6-10 PubMed

Diabetologia. 2014 Jan;57(1):4-15 PubMed

Diabetes. 2014 Apr;63(4):1353-65 PubMed

Vasc Med. 2013 Dec;18(6):331-9 PubMed

Int J Vasc Med. 2014;2014:589412 PubMed

Front Endocrinol (Lausanne). 2014 Apr 09;5:44 PubMed

Am J Physiol Heart Circ Physiol. 2014 Sep 15;307(6):H869-79 PubMed

J Diabetes Complications. 2015 Jul;29(5):686-90 PubMed

Vasc Med. 2016 Feb;21(1):3-11 PubMed

Cytotherapy. 2016 Feb;18(2):253-62 PubMed

Clin Chim Acta. 2016 Apr 1;455:1-6 PubMed

Mech Ageing Dev. 2016 Oct;159:49-62 PubMed

Tissue Eng Part B Rev. 2016 Oct;22(5):371-382 PubMed

Stem Cells Int. 2016;2016:1803989 PubMed

Int J Cardiol. 2017 Jan 15;227:833-839 PubMed

Diabetes Res Clin Pract. 2017 Feb;124:84-92 PubMed

World J Cardiol. 2017 Jan 26;9(1):1-13 PubMed

Diabetes Res Clin Pract. 2017 Apr;126:263-271 PubMed

Stem Cells Transl Med. 2017 May;6(5):1316-1320 PubMed

Stem Cell Rev. 2018 Feb;14(1):82-91 PubMed

Cell Stem Cell. 2018 Aug 2;23(2):210-225.e6 PubMed

J Exp Med. 2018 Oct 1;215(10):2497-2508 PubMed

Science. 1997 Feb 14;275(5302):964-7 PubMed

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