Advances in Optoacoustic Neurotomography of Animal Models
Language English Country England, Great Britain Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
31662189
DOI
10.1016/j.tibtech.2019.07.012
PII: S0167-7799(19)30186-6
Knihovny.cz E-resources
- Keywords
- MSOT, hemodynamic response, neuroimaging, noninvasive interrogation, photoacoustic,
- MeSH
- Humans MeSH
- Models, Animal MeSH
- Neuroimaging * MeSH
- Photoacoustic Techniques * MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
Unlike traditional optical methods, optoacoustic imaging is less sensitive to scattering of ballistic photons, so it is capable of high-resolution interrogation at a greater depth. By integrating video-rate visualization with multiplexing and sensing a range of endogenous and exogenous chromophores, optoacoustic imaging has matured into a versatile noninvasive investigation modality with rapidly expanding use in biomedical research. We review the principal features of the technology and discuss recent advances it has enabled in structural, functional, and molecular neuroimaging in small-animal models. In extending the boundaries of noninvasive observation beyond the reach of customary photonic methods, the latest developments in optoacoustics have substantially advanced neuroimaging inquiry, with promising implications for basic and translational studies.
References provided by Crossref.org
