• This record comes from PubMed

Helsinki by nature: The Nature Step to Respiratory Health

. 2019 ; 9 () : 57. [epub] 20191030

Status PubMed-not-MEDLINE Language English Country Great Britain, England Media electronic-ecollection

Document type Journal Article, Review

Grant support
001 World Health Organization - International

BACKGROUND: The Nature Step to Respiratory Health was the overarching theme of the 12th General Meeting of the Global Alliance against Chronic Respiratory Diseases (GARD) in Helsinki, August 2018. New approaches are needed to improve respiratory health and reduce premature mortality of chronic diseases by 30% till 2030 (UN Sustainable Development Goals, SDGs). Planetary health is defined as the health of human civilization and the state of the natural systems on which it depends. Planetary health and human health are interconnected, and both need to be considered by individuals and governments while addressing several SDGs. RESULTS: The concept of the Nature Step has evolved from innovative research indicating, how changed lifestyle in urban surroundings reduces contact with biodiverse environments, impoverishes microbiota, affects immune regulation and increases risk of NCDs. The Nature Step calls for strengthening connections to nature. Physical activity in natural environments should be promoted, use of fresh vegetables, fruits and water increased, and consumption of sugary drinks, tobacco and alcohol restricted. Nature relatedness should be part of everyday life and especially emphasized in the care of children and the elderly. Taking "nature" to modern cities in a controlled way is possible but a challenge for urban planning, nature conservation, housing, traffic arrangements, energy production, and importantly for supplying and distributing food. Actions against the well-known respiratory risk factors, air pollution and smoking, should be taken simultaneously. CONCLUSIONS: In Finland and elsewhere in Europe, successful programmes have been implemented to reduce the burden of respiratory disorders and other NCDs. Unhealthy behaviour can be changed by well-coordinated actions involving all stakeholders. The growing public health concern caused by NCDs in urban surroundings cannot be solved by health care alone; a multidisciplinary approach is mandatory.

Allergy and Asthma Network Vienna VA USA

Clinic of Children's Diseases Institute of Clinical Medicine and Department of Public Health Institute of Health Sciences Vilnius University Vilnius Lithuania

Department of Dermatology Allergology and Venereology Helsinki University Hospital Helsinki Finland

Department of Medicine University of Cape Town Cape Town South Africa

Department of Medicine University of Illinois at Chicago Chicago USA

Department of Pediatrics Medical School Federal University of Minas Gerais Belo Horizonte Brazil

Department of Prevention of Environmental Hazards and Allergology Medical University of Warsaw Warsaw Poland

Department of Public Health and Primary Care Leiden University Medical Center Leiden The Netherlands

Department of Pulmonary Diseases Cerrahpasa Faculty of Medicine Istanbul University Cerrahpasa Istanbul Turkey

Department of Pulmonary Diseases Faculty of Medicine Celal Bayar University Manisa Turkey

Department of Respiratory Diseases and Tuberculosis University Hospital Olomouc Olomouc Czech Republic

Department of Respiratory Medicine National Institute of Diseases of the Chest and Hospital Dhaka Bangladesh

Department of Thoracic Diseases Ain Shams Faculty of Medicine Abbassia Cairo Egypt

Dept of Pulmonary Medicine Postgraduate Institute of Medical Education and Research Chandigarh India

Division of Allergology and Respiratory Medicine Showa University School of Medicine Tokyo Japan

Division of Internal Medicine Asthma and Allergy Barlicki University Hospital Medical University of Lodz Lodz Poland

Environmental Policy Centre Finnish Environment Institute Helsinki Finland

EuroAsian Respiratory Society Astana City Kazakhstan

FILHA Finnish Lung Health Association Helsinki Finland

Global Allergy and Asthma Patient Platform Vienna Austria

Global Alliance Against Chronic Respiratory Diseases Geneva Switzerland

Global Alliance Against Respiratory Diseases Helsinki Finland

Hispanic American Allergy Asthma and Immunology Association Marina Del Rey California USA

Hospital Dr Agostinho Neto Praia Cabo Verde

Hospital Universitario y Facultad de Medicina Monterrey Nuevo Leon Mexico

Immunoallergology Department Hospital da Luz Lisboa Lisbon Portugal

Investigaciones en Alergia y Enfermedades Respiratorias Buenos Aires Argentina

ISGlobAL Centre for Research in Environmental Epidemiology Barcelona Spain

Istituto di Fisiologia Clinica CNR Pisa Italy

Istituto per la Ricerca e l'Innovazione Biomedica Palermo Italy

Kyrgyzstan National Centre of Cardiology and Internal Medicine Euro Asian Respiratory Society Bishkek Kyrgyzstan

Laboratory of Clinical Immunology Department of Microbiology and Immunology KU Leuven Louvain Belgium

Life and Health Sciences Research Institute ICVS School of Medicine University of Minho Braga Portugal

MACVIA France Fondation Partenariale FMC VIA LR CHRU Arnaud de Villeneuve Montpellier France

Management of NCDs WHO Geneva Switzerland

National Center for Research in Chronic Respiratory Diseases Tishreen University School of Medicine Latakia Syria

National Institute for Health and Welfare Helsinki Finland

National Institute of Pneumology M Nasta Bucharest Romania

ProAR Nucleo de Excelencia em Asma Federal University of Bahia Vitória Da Conquista Brazil

Pulmonology Department Ivane Javakhishvili Tbilisi State University Chapidze Emergency Cardiology Center Tbilisi Georgia

Pulmonology Department Maputo Central Hospital Maputo Mozambique

Respiratory Care Center University Medical Center Ho Chi Minh City Vietnam

Shahid Beheshti University of Medical Sciences Tehran Iran

Skin and Allergy Hospital Helsinki University Hospital University of Helsinki Helsinki Finland

The Allergy and Asthma Institute Islamabad Pakistan

The Hospital for Sick Children Research Institute and Della Lana School of Public Health University of Toronto Toronto ON Canada

Zhongshan Hospital Fudan University Shanghai Respiratory Research Institute Shanghai China

See more in PubMed

Bousquet J, Khaltaev N. Global surveillance, prevention and control of chronic respiratory diseases: a comprehensive approach. Geneva: World Health Organization; 2007.

Marteau TM. Changing minds about changing behaviour. Lancet. 2018;391(10116):116–117. doi: 10.1016/S0140-6736(17)33324-X. PubMed DOI

Transforming our world: The 2030 agenda for sustainable development. A/RES/70/1. United Nations 2015.

United Nations. The Sustainable Development Goals (SDGs). https://www.un.org/sustainabledevelopment/sustainable-development-goals. Accessed 31 Mar 2019.

Time to deliver: report of the WHO independent high-level commission on non-communicable diseases.: World Health Organization; 2018.

von Hertzen L, Beutler B, Bienenstock J, Blaser M, Cani PD, Eriksson J, et al. Helsinki alert of biodiversity and health. Ann Med. 2015;47(3):218–225. doi: 10.3109/07853890.2015.1010226. PubMed DOI

Independent Group of Scientists appointed by the Secretary-General . Global sustainable development report 2019: the future is now—science for achieving sustainable development. New York: United Nations; 2019.

World Urbanization Prospects . The 2018 revision. Department of Economic and Social Affairs. New York: United Nations; 2018.

Connecting Global Priorities: Biodiversity and Human Health. A state of knowledge review 2015. World Health Organization and the Convention on Biological Diversity; 2015.

Maio S, Baldacci S, Carrozzi L, Pistelli F, Angino A, Simoni M, et al. Respiratory symptoms/diseases prevalence is still increasing: a 25-yr population study. Respir Med. 2016;110:58–65. doi: 10.1016/j.rmed.2015.11.006. PubMed DOI

Flandroy L, Poutahidis T, Berg G, Clarke G, Dao MC, Decaestecker E, et al. The impact of human activities and lifestyles on the interlinked microbiota and health of humans and of ecosystems. Sci Total Environ. 2018;627:1018–1038. doi: 10.1016/j.scitotenv.2018.01.288. PubMed DOI

George ES, Rosenkranz RR, Kolt GS. Chronic disease and sitting time in middle-aged Australian males: findings from the 45 and up study. Int J Behav Nutr Phys Act. 2013;10:20. doi: 10.1186/1479-5868-10-20. PubMed DOI PMC

Tomita A, Vandormael AM, Cuadros D, Di Minin E, Heikinheimo V, Tanser F, et al. Green environment and incident depression in South Africa: a geospatial analysis and mental health implications in a resource-limited setting. Lancet Planet Health. 2017;1(4):e152–e162. doi: 10.1016/S2542-5196(17)30063-3. PubMed DOI PMC

Sarkar C, Webster C, Gallacher J. Residential greenness and prevalence of major depressive disorders: a cross-sectional, observational, associational study of 94 879 adult UK Biobank participants. Lancet Planet Health. 2018;2(4):e162–e173. doi: 10.1016/S2542-5196(18)30051-2. PubMed DOI

Louv R. Last child in the woods. London: Atlantic Books; 2009.

Lovasi GS, Quinn JW, Neckerman KM, Perzanowski MS, Rundle A. Children living in areas with more street trees have lower prevalence of asthma. J Epidemiol Community Health. 2008;62(7):647–649. doi: 10.1136/jech.2007.071894. PubMed DOI PMC

Fuertes E, Markevych I, Bowatte G, Gruzieva O, Gehring U, Becker A, et al. Residential greenness is differentially associated with childhood allergic rhinitis and aeroallergen sensitization in seven birth cohorts. Allergy. 2016;71(10):1461–1471. doi: 10.1111/all.12915. PubMed DOI

Lovasi GS, O’Neil-Dunne JP, Lu JW, Sheehan D, Perzanowski MS, Macfaden SW, et al. Urban tree canopy and asthma, wheeze, rhinitis, and allergic sensitization to tree pollen in a New York City birth cohort. Environ Health Perspect. 2013;121(4):494–500. doi: 10.1289/ehp.1205513. PubMed DOI PMC

Dadvand P, Villanueva CM, Font-Ribera L, Martinez D, Basagana X, Belmonte J, et al. Risks and benefits of green spaces for children: a cross-sectional study of associations with sedentary behavior, obesity, asthma, and allergy. Environ Health Perspect. 2014;122(12):1329–1335. doi: 10.1289/ehp.1308038. PubMed DOI PMC

Cilluffo G, Ferrante G, Fasola S, Montalbano L, Malizia V, Piscini A, et al. Associations of greenness, greyness and air pollution exposure with children’s health: a cross-sectional study in Southern Italy. Environ Health. 2018;17(1):86. doi: 10.1186/s12940-018-0430-x. PubMed DOI PMC

Pacieência IRJ, Silva D, Martins C, Mendes F, Rama T, et al. School environment associates with lung function and autonomic nervous system activity in children: a crosssectional study. Sci Rep. 2019;9:15156. doi: 10.1038/s41598-019-51659-y. PubMed DOI PMC

White MP, Alcock I, Grellier J, Wheeler BW, Hartig T, Warber SL, et al. Spending at least 120 minutes a week in nature is associated with good health and wellbeing. Sci Rep. 2019;9(1):7730. doi: 10.1038/s41598-019-44097-3. PubMed DOI PMC

Living Planet Report—2018. In: Aiming higher. M Grooten, REA Almond, editors. WWF: Gland, Switzerland; 2018.

Global assessment report on biodiversity and ecosystem services of the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services. In: ES Brondizio, J Settele, S Díaz, HT Ngo, editors. IPBES Secretariat: Bonn, Germany, 2019.

Rockstrom J, Steffen W, Noone K, Persson A, Chapin FS, 3rd, Lambin EF, et al. A safe operating space for humanity. Nature. 2009;461(7263):472–475. doi: 10.1038/461472a. PubMed DOI

Campbell-Lendrum D, Pruss-Ustun A. Climate change, air pollution and noncommunicable diseases. Bull World Health Organ. 2019;97(2):160–161. doi: 10.2471/BLT.18.224295. PubMed DOI PMC

Landrigan P, Fuller R, Haines A, Watts N, McCarthy G. Pollution prevention and climate change mitigation: measuring the health benefits of comprehensive interventions. Lancet Planet Health. 2018;2(12):e515–e516. doi: 10.1016/S2542-5196(18)30226-2. PubMed DOI

Kostic AD, Gevers D, Siljander H, Vatanen T, Hyotylainen T, Hamalainen AM, et al. The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetes. Cell Host Microbe. 2015;17(2):260–273. doi: 10.1016/j.chom.2015.01.001. PubMed DOI PMC

Montoya JM, Pimm SL, Sole RV. Ecological networks and their fragility. Nature. 2006;442(7100):259–264. doi: 10.1038/nature04927. PubMed DOI

Convention on Biological Diversity 1992. United Nations; 1992.

von Hertzen L, Hanski I, Haahtela T. Natural immunity. Biodiversity loss and inflammatory diseases are two global megatrends that might be related. EMBO Rep. 2011;12(11):1089–1093. doi: 10.1038/embor.2011.195. PubMed DOI PMC

Hanski I, von Hertzen L, Fyhrquist N, Koskinen K, Torppa K, Laatikainen T, et al. Environmental biodiversity, human microbiota, and allergy are interrelated. Proc Natl Acad Sci USA. 2012;109(21):8334–8339. doi: 10.1073/pnas.1205624109. PubMed DOI PMC

Haahtela T, Holgate S, Pawankar R, Akdis CA, Benjaponpitak S, Caraballo L, et al. The biodiversity hypothesis and allergic disease: world allergy organization position statement. World Allergy Organ J. 2013;6(1):3. doi: 10.1186/1939-4551-6-3. PubMed DOI PMC

Rook GA. Regulation of the immune system by biodiversity from the natural environment: an ecosystem service essential to health. Proc Natl Acad Sci USA. 2013;110(46):18360–18367. doi: 10.1073/pnas.1313731110. PubMed DOI PMC

Haahtela T. A biodiversity hypothesis. Allergy. 2019;74(8):1445–1456. PubMed

Martinez FD, Guerra S. Early origins of asthma. Role of microbial dysbiosis and metabolic dysfunction. Am J Respir Crit Care Med. 2018;197(5):573–579. doi: 10.1164/rccm.201706-1091PP. PubMed DOI PMC

Kirjavainen PV, Karvonen AM, Adams RI, Taubel M, Roponen M, Tuoresmaki P, et al. Farm-like indoor microbiota in non-farm homes protects children from asthma development. Nat Med. 2019;25(7):1089–1095. doi: 10.1038/s41591-019-0469-4. PubMed DOI PMC

Stein MM, Hrusch CL, Gozdz J, Igartua C, Pivniouk V, Murray SE, et al. Innate immunity and asthma risk in amish and hutterite farm children. N Engl J Med. 2016;375(5):411–421. doi: 10.1056/NEJMoa1508749. PubMed DOI PMC

Tjalvin G, Mikkelsen KE, Apelseth TO, Hollund BE, Svanes C, Van Do T. Hypersensitivity pneumonitis in farmers: improving etiologic diagnosis to optimize counselling. J Agromed. 2019 doi: 10.1080/1059924X.2019.1605954. PubMed DOI

Ruokolainen L, Lehtimaki J, Karkman A, Haahtela T, von Hertzen L, Fyhrquist N. Holistic view on health: two protective layers of biodiversity. Ann Zool Fenn. 2017;25(1–4):39–49. doi: 10.5735/086.054.0106. DOI

Rautava S, Luoto R, Salminen S, Isolauri E. Microbial contact during pregnancy, intestinal colonization and human disease. Nat Rev Gastroenterol Hepatol. 2012;9(10):565–576. doi: 10.1038/nrgastro.2012.144. PubMed DOI

Lax S, Smith DP, Hampton-Marcell J, Owens SM, Handley KM, Scott NM, et al. Longitudinal analysis of microbial interaction between humans and the indoor environment. Science. 2014;345(6200):1048–1052. doi: 10.1126/science.1254529. PubMed DOI PMC

Karkman A, Lehtimaki J, Ruokolainen L. The ecology of human microbiota: dynamics and diversity in health and disease. Ann N Y Acad Sci. 2017;1399(1):78–92. doi: 10.1111/nyas.13326. PubMed DOI

Ottman N, Ruokolainen L, Suomalainen A, Sinkko H, Karisola P, Lehtimaki J, et al. Soil exposure modifies the gut microbiota and supports immune tolerance in a mouse model. J Allergy Clin Immunol. 2019;143(3):1198-206 e12. doi: 10.1016/j.jaci.2018.06.024. PubMed DOI

Logan AC, Jacka FN, Prescott SL. Immune-microbiota interactions: dysbiosis as a global health issue. Curr Allergy Asthma Rep. 2016;16(2):13. doi: 10.1007/s11882-015-0590-5. PubMed DOI

Langella P, Guarner F, Martin R. Editorial: next-generation probiotics: from commensal bacteria to novel drugs and food supplements. Front Microbiol. 2019;10:1973. doi: 10.3389/fmicb.2019.01973. PubMed DOI PMC

Sender R, Fuchs S, Milo R. Revised estimates for the number of human and bacteria cells in the body. PLoS Biol. 2016;14(8):e1002533. doi: 10.1371/journal.pbio.1002533. PubMed DOI PMC

Grice EA, Segre JA. The human microbiome: our second genome. Annu Rev Genomics Hum Genet. 2012;13:151–170. doi: 10.1146/annurev-genom-090711-163814. PubMed DOI PMC

Harsch IA, Konturek PC. The role of gut microbiota in obesity and type 2 and type 1 diabetes mellitus: new insights into “old” diseases. Med Sci (Basel) 2018;6(2):32. PubMed PMC

von Hertzen L, Haahtela T. Disconnection of man and the soil: reason for the asthma and atopy epidemic? J Allergy Clin Immunol. 2006;117(2):334–344. doi: 10.1016/j.jaci.2005.11.013. PubMed DOI

Parajuli A, Gronroos M, Siter N, Puhakka R, Vari HK, Roslund MI, et al. Urbanization reduces transfer of diverse environmental microbiota indoors. Front Microbiol. 2018;9:84. doi: 10.3389/fmicb.2018.00084. PubMed DOI PMC

Haahtela T, Laatikainen T, Alenius H, Auvinen P, Fyhrquist N, Hanski I, et al. Hunt for the origin of allergy—comparing the Finnish and Russian Karelia. Clin Exp Allergy. 2015;45(5):891–901. doi: 10.1111/cea.12527. PubMed DOI

Ruokolainen L, Paalanen L, Karkman A, Laatikainen T, von Hertzen L, Vlasoff T, et al. Significant disparities in allergy prevalence and microbiota between the young people in Finnish and Russian Karelia. Clin Exp Allergy. 2017;47(5):665–674. doi: 10.1111/cea.12895. PubMed DOI

Song Y, Khoo SK, Lee KH, Makela M, Haahtela T, LeSouef P, et al. Dual responses of CD14 methylation to distinct environments: a role in asthma and allergy. Eur Respir J. 2017;50(6):1701228. doi: 10.1183/13993003.01228-2017. PubMed DOI

Zhang Q, Cao X. Epigenetic regulation of the innate immune response to infection. Nat Rev Immunol. 2019;19(7):417–432. doi: 10.1038/s41577-019-0151-6. PubMed DOI

Greener Cities Partnership (UN-Habitat and UN Environment). https://new.unhabitat.org/greener-cities-partnership. Accessed 2 Oct 2019.

EU Commission H2020 programme. https://ec.europa.eu/inea/en/horizon-2020/smart-cities-communities. Accessed 30 Sept 2019.

Haahtela T, Hanski I, von Hertzen L, Jousilahti P, Laatikainen T, Makela M, et al. “ Nature step” to prevent noncommunicable inflammatory disease. Duodecim. 2017;133(1):19–26. PubMed

Global strategy on diet, physical activity and health—2004. Geneva: World Health Organization; 2004.

Rico-Campa A, Martinez-Gonzalez MA, Alvarez-Alvarez I, Mendonca RD, de la Fuente-Arrillaga C, Gomez-Donoso C, et al. Association between consumption of ultra-processed foods and all cause mortality: sUN prospective cohort study. BMJ. 2019;365:l1949. doi: 10.1136/bmj.l1949. PubMed DOI PMC

Bousquet J, Kiley J, Bateman ED, Viegi G, Cruz AA, Khaltaev N, et al. Prioritised research agenda for prevention and control of chronic respiratory diseases. Eur Respir J. 2010;36(5):995–1001. doi: 10.1183/09031936.00012610. PubMed DOI

Haahtela T, von Hertzen L, Makela M, Hannuksela M, Allergy Programme Working G Finnish allergy programme 2008–2018—time to act and change the course. Allergy. 2008;63(6):634–645. doi: 10.1111/j.1398-9995.2008.01712.x. PubMed DOI

von Hertzen LC, Savolainen J, Hannuksela M, Klaukka T, Lauerma A, Makela MJ, et al. Scientific rationale for the Finnish Allergy Programme 2008–2018: emphasis on prevention and endorsing tolerance. Allergy. 2009;64(5):678–701. doi: 10.1111/j.1398-9995.2009.02024.x. PubMed DOI

Gronroos M, Parajuli A, Laitinen OH, Roslund MI, Vari HK, Hyoty H, et al. Short-term direct contact with soil and plant materials leads to an immediate increase in diversity of skin microbiota. Microbiologyopen. 2019;8(3):e00645. doi: 10.1002/mbo3.645. PubMed DOI PMC

Haahtela T, Valovirta E, Bousquet J, Makela M. The Finnish allergy programme 2008–2018 works. Eur Respir J. 2017;49(6):1700470. doi: 10.1183/13993003.00470-2017. PubMed DOI

Hisinger-Molkanen H, Pallasaho P, Haahtela T, Lindqvist A, Sovijarvi A, Piirila P. The increase of asthma prevalence has levelled off and symptoms decreased in adults during 20 years from 1996 to 2016 in Helsinki, Finland. Respir Med. 2019;155:121–126. doi: 10.1016/j.rmed.2019.07.014. PubMed DOI

Saaristo T, Peltonen M, Keinanen-Kiukaanniemi S, Vanhala M, Saltevo J, Niskanen L, et al. National type 2 diabetes prevention programme in Finland: FIN-D2D. Int J Circumpolar Health. 2007;66(2):101–112. doi: 10.3402/ijch.v66i2.18239. PubMed DOI

Mikola M. Taste classes support children’s growth into confident experimenters and consumers. https://www.sitra.fi/en/articles/markku-mikola-taste-classes-support-childrens-growth-confident-experimenters/. Accessed 12 July 2019.

Hegerl G, Stott P. Atmospheric science. From past to future warming. Science. 2014;343(6173):844–845. doi: 10.1126/science.1249368. PubMed DOI

Haines A, Ebi K. The imperative for climate action to protect health. N Engl J Med. 2019;380(3):263–273. doi: 10.1056/NEJMra1807873. PubMed DOI

Haines A, Kovats RS, Campbell-Lendrum D, Corvalan C. Climate change and human health: impacts, vulnerability, and mitigation. Lancet. 2006;367(9528):2101–2109. doi: 10.1016/S0140-6736(06)68933-2. PubMed DOI

Baro F, Chaparro L, Gomez-Baggethun E, Langemeyer J, Nowak DJ, Terradas J. Contribution of ecosystem services to air quality and climate change mitigation policies: the case of urban forests in Barcelona, Spain. Ambio. 2014;43(4):466–479. doi: 10.1007/s13280-014-0507-x. PubMed DOI PMC

Whitmee S, Haines A, Beyrer C, Boltz F, Capon AG, de Souza Dias BF, et al. Safeguarding human health in the Anthropocene epoch: report of The Rockefeller Foundation-Lancet Commission on planetary health. Lancet. 2015;386(10007):1973–2028. doi: 10.1016/S0140-6736(15)60901-1. PubMed DOI

Myers SS, Gaffikin L, Golden CD, Ostfeld RS, Redford KH, Ricketts TH, et al. Human health impacts of ecosystem alteration. Proc Natl Acad Sci USA. 2013;110(47):18753–18760. doi: 10.1073/pnas.1218656110. PubMed DOI PMC

Raudsepp-Hearne C, Peterson GD, Bennett EM. Ecosystem service bundles for analyzing tradeoffs in diverse landscapes. Proc Natl Acad Sci USA. 2010;107(11):5242–5247. doi: 10.1073/pnas.0907284107. PubMed DOI PMC

Cohen AJ, Brauer M, Burnett R, Anderson HR, Frostad J, Estep K, et al. Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015. Lancet. 2017;389(10082):1907–1918. doi: 10.1016/S0140-6736(17)30505-6. PubMed DOI PMC

Ambient (outdoor) air quality and health. WHO fact sheet. https://www.who.int/en/news-room/fact-sheets/detail/ambient-(outdoor)-air-quality-and-health. Accessed 12 July 2019.

Landrigan PJ, Fuller R, Acosta NJR, Adeyi O, Arnold R, Basu NN, et al. The Lancet Commission on pollution and health. Lancet. 2018;391(10119):462–512. doi: 10.1016/S0140-6736(17)32345-0. PubMed DOI

Du Y, Xu X, Chu M, Guo Y, Wang J. Air particulate matter and cardiovascular disease: the epidemiological, biomedical and clinical evidence. J Thorac Dis. 2016;8(1):E8–E19. PubMed PMC

Thurston GD, Kipen H, Annesi-Maesano I, Balmes J, Brook RD, Cromar K, et al. A joint ERS/ATS policy statement: what constitutes an adverse health effect of air pollution? An analytical framework. Eur Respir J. 2017;49(1):1600419. doi: 10.1183/13993003.00419-2016. PubMed DOI PMC

Orellano P, Quaranta N, Reynoso J, Balbi B, Vasquez J. Effect of outdoor air pollution on asthma exacerbations in children and adults: systematic review and multilevel meta-analysis. PLoS ONE. 2017;12(3):e0174050. doi: 10.1371/journal.pone.0174050. PubMed DOI PMC

Li J, Sun S, Tang R, Qiu H, Huang Q, Mason TG, et al. Major air pollutants and risk of COPD exacerbations: a systematic review and meta-analysis. Int J Chron Obstruct Pulmon Dis. 2016;11:3079–3091. doi: 10.2147/COPD.S122282. PubMed DOI PMC

Weinreich G, Wessendorf TE, Pundt N, Weinmayr G, Hennig F, Moebus S, et al. Association of short-term ozone and temperature with sleep disordered breathing. Eur Respir J. 2015;46(5):1361–1369. doi: 10.1183/13993003.02255-2014. PubMed DOI

Behrendt H, Alessandrini F, Buters J, Kramer U, Koren H, Ring J. Environmental pollution and allergy: historical aspects. Chem Immunol Allergy. 2014;100:268–277. doi: 10.1159/000359918. PubMed DOI

Ozawa K, Furuta M, Miyao M, Terao C, Kimura M, Sugata K, et al. Medical consultation rate of allergic rhinitis and pollinosis surveillance in Aichi, Japan. Nagoya J Med Sci. 1994;57(1–4):51–60. PubMed

Wendling ZA, Emerson JW, Esty DC, Levy MA, de Sherbinin A, et al. 2018 Environmental performance index. New Haven, CT: Yale Center for Environmental Law & Policy. Yale Center for Environmental Law & Policy, Yale University; 2018. https://epi.yale.edu/.

Pelkonen MK, Notkola IK, Laatikainen TK, Jousilahti P. 30-year trends in asthma and the trends in relation to hospitalization and mortality. Respir Med. 2018;142:29–35. doi: 10.1016/j.rmed.2018.07.012. PubMed DOI

WHO report on the global tobacco epidemic, 2017: monitoring tobacco use and prevention policies. World Health Organization; 2017.

MPOWER in action. Defeating the global epidemic. https://www.who.int/tobacco/mpower/publications/brochure_2013/en/. Accessed 12 July 2019.

Jiang XQ, Mei XD, Feng D. Air pollution and chronic airway diseases: what should people know and do? J Thorac Dis. 2016;8(1):E31–E40. PubMed PMC

Ferkol TW, Farber HJ, La Grutta S, Leone FT, Marshall HM, Neptune E, et al. Electronic cigarette use in youths: a position statement of the Forum of International Respiratory Societies. Eur Respir J. 2018;51(5):1800278. doi: 10.1183/13993003.00278-2018. PubMed DOI

Advisory Note. Waterpipe tobacco smoking: health effects, research needs and recommended actions for regulators. 2nd edition.: WHO Study Group on Tobacco Product Regulation (TobReg). World Health Organization; 2015.

Branston JR, Sweanor D. Big tobacco, E-cigarettes, and a road to the smoking endgame. Int J Drug Policy. 2016;29:14–18. doi: 10.1016/j.drugpo.2015.12.023. PubMed DOI

Timberlake DS, Laitinen U, Kinnunen JM, Rimpela AH. Strategies and barriers to achieving the goal of Finland’s tobacco endgame. Tob Control. 2019 doi: 10.1136/tobaccocontrol-2018-054779. PubMed DOI PMC

Tobacco-Free Finland 2020. https://svautonsuomi.fi/en/. Accessed 12 July 2019.

Nieuwenhuijsen MJ, Khreis H, Triguero-Mas M, Gascon M, Dadvand P. Fifty shades of green: pathway to healthy urban living. Epidemiology. 2017;28(1):63–71. doi: 10.1097/EDE.0000000000000549. PubMed DOI

Tobacco and its enviromental impact: an overview. World Health Organization 2017. Report No.: 978-92-4-151249-7.

Carlos WG, Crotty Alexander LE, Gross JE, Dela Cruz CS, Keller JM, Pasnick S, et al. Vaping-associated pulmonary illness (VAPI) Am J Respir Crit Care Med. 2019;200(7):P13–P14. doi: 10.1164/rccm.2007P13. PubMed DOI

Springmann M, Clark M, Mason-D’Croz D, Wiebe K, Bodirsky BL, Lassaletta L, et al. Options for keeping the food system within environmental limits. Nature. 2018;562(7728):519–525. doi: 10.1038/s41586-018-0594-0. PubMed DOI

Yip CSC, Chan W, Fielding R. The associations of fruit and vegetable intakes with burden of diseases: a systematic review of meta-analyses. J Acad Nutr Diet. 2019;119(3):464–481. doi: 10.1016/j.jand.2018.11.007. PubMed DOI

Collaborators GBDA. Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2018;392(10152):1015–1035. doi: 10.1016/S0140-6736(18)31310-2. PubMed DOI PMC

Sberro H, Fremin BJ, Zlitni S, Edfors F, Greenfield N, Snyder MP, et al. Large-scale analyses of human microbiomes reveal thousands of small, novel genes. Cell. 2019;178(5):1245-59 e14. doi: 10.1016/j.cell.2019.07.016. PubMed DOI PMC

Erhola M, Vasankari T, Jormanainen V, Toppila-Salmi S, Herrala J, Haahtela T. 25 years of respiratory health in Finland. Lancet Respir Med. 2019;7(5):e16. doi: 10.1016/S2213-2600(19)30122-5. PubMed DOI

Vartiainen E. The North Karelia Project: cardiovascular disease prevention in Finland. Glob Cardiol Sci Pract. 2018;2018(2):13. PubMed PMC

Valiulis A, Bousquet J, Veryga A, Suprun U, Sergeenko D, Cebotari S, et al. Vilnius Declaration on chronic respiratory diseases: multisectoral care pathways embedding guided self-management, mHealth and air pollution in chronic respiratory diseases. Clin Transl Allergy. 2019;9:7. doi: 10.1186/s13601-019-0242-2. PubMed DOI PMC

Political declaration of the third high-level meeting of the General Assembly on the prevention and control of non-communicable diseases.: United Nations; 2018. A/RES/73/2.

First WHO Global Conference on air pollution and health. Improving air quality, combatting climate change- saving lives.: World Health Organization; 2018.

Ramanathan V, Samet J, Neira M, Sorondo MS. Air pollution, climate change, and health: a declaration from the Vatican. Ann Am Thorac Soc. 2018;15(9):1027–1029. doi: 10.1513/AnnalsATS.201805-319ED. PubMed DOI

Bousquet J, Bedbrook A, Czarlewski W, Onorato GL, Arnavielhe S, Laune D, et al. Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma. Clin Transl Allergy. 2019;9:16. doi: 10.1186/s13601-019-0252-0. PubMed DOI PMC

Bousquet J, Hellings PW, Agache I, Amat F, Annesi-Maesano I, Ansotegui IJ, et al. Allergic rhinitis and its impact on asthma (ARIA) phase 4 (2018): change management in allergic rhinitis and asthma multimorbidity using mobile technology. J Allergy Clin Immunol. 2019;143(3):864–879. doi: 10.1016/j.jaci.2018.08.049. PubMed DOI

Find record

Citation metrics

Loading data ...

Archiving options

Loading data ...