Polyoxazolines are a new promising class of polymers for biomedical applications. Antibiofouling polyoxazoline coatings can suppress bacterial colonization of medical devices, which can cause infections to patients. However, the creation of oxazoline-based films using conventional methods is difficult. This study presents a new way to produce plasma polymerized oxazoline-based films with antibiofouling properties and good biocompatibility. The films were created via plasma deposition from 2-methyl-2-oxazoline vapors in nitrogen atmospheric pressure dielectric barrier discharge. Diverse film properties were achieved by increasing the substrate temperature at the deposition. The physical and chemical properties of plasma polymerized polyoxazoline films were studied by SEM, EDX, FTIR, AFM, depth-sensing indentation technique, and surface energy measurement. After tuning of the deposition parameters, films with a capacity to resist bacterial biofilm formation were achieved. Deposited films also promote cell viability.

Centre of Polymer Systems Tomas Bata University in Zlín Trida Tomase Bati 5678 760 01 Zlín Czech Republic

Department of Mathematics and Physics Faculty of Military Technology University of Defence in Brno Kounicova 65 662 10 Brno Czech Republic

Department of Physical Electronics Faculty of Science Masaryk University Kotlářská 2 611 37 Brno Czech Republic

Faculty of Chemistry Institute of Food Science and Biotechnology Brno University of Technology Purkyňova 118 612 00 Brno Czech Republic

Faculty of Chemistry Institute of Physical and Applied Chemistry Brno University of Technology Purkyňova 118 612 00 Brno Czech Republic

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