Comparison of Plasma-Polymerized Thin Films Deposited from 2-Methyl-2-oxazoline and 2-Ethyl-2-oxazoline: I Film Properties
Jazyk angličtina Země Švýcarsko Médium electronic
Typ dokumentu časopisecké články
Grantová podpora
DKRVO RP/CPS/2022/005, DKRVO RP/CPS/2022/001, DKRVO RP/CPS/2022/002
ministry of education, youth and sports
DKRVO
Ministry of Defence
PubMed
38139283
PubMed Central
PMC10743558
DOI
10.3390/ijms242417455
PII: ijms242417455
Knihovny.cz E-zdroje
- Klíčová slova
- antibiofouling, plasma polymer, poly(2-oxazoline),
- MeSH
- antibakteriální látky * farmakologie MeSH
- Escherichia coli MeSH
- oxazoly * farmakologie chemie MeSH
- polymerizace MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- 2-ethyl-2-oxazoline MeSH Prohlížeč
- 2-methyl-2-oxazoline MeSH Prohlížeč
- antibakteriální látky * MeSH
- oxazoly * MeSH
Poly(2-oxazoline) is a promising new class of polymeric materials due to their antibiofouling properties and good biocompatibility. Poly(2-oxazoline) coatings can be deposited on different substrates via plasma polymerization, which can be more advantageous than other coating methods. The aim of this study is to deposit poly(2-oxazoline) coatings using a surface dielectric barrier discharge burning in nitrogen at atmospheric pressure using 2-methyl-2-oxazoline and 2-ethyl-2-oxazoline vapours as monomers and compare the film properties. For the comparison, the antibacterial and cytocompatibility tests were peformed according to ISO norms. The antibacterial tests showed that all the deposited films were highly active against Staphylococcus aureus and Escherichia coli bacteria. The chemical composition of the films was studied using FTIR and XPS, and the film surface's properties were studied using AFM and surface energy measurement. The cytocompatibility tests showed good cytocompatibility of all the deposited films. However, the films deposited from 2-methyl-2-oxazoline exhibit better cytocompatibility. This difference can be explained by the different chemical compositions and surface morphologies of the films deposited from different monomers.
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