Managing childhood allergies and immunodeficiencies during respiratory virus epidemics - The 2020 COVID-19 pandemic: A statement from the EAACI-section on pediatrics

. 2020 Jul ; 31 (5) : 442-448. [epub] 20200531

Jazyk angličtina Země Velká Británie, Anglie Médium print-electronic

Typ dokumentu časopisecké články, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/pmid32319129

While the world is facing an unprecedented pandemic with COVID-19, patients with chronic diseases need special attention and if warranted adaptation of their regular treatment plan. In children, allergy and asthma are among the most prevalent non-communicable chronic diseases, and healthcare providers taking care of these patients need guidance. At the current stage of knowledge, children have less severe symptoms of COVID-19, and severe asthma and immunodeficiency are classified as risk factors. In addition, there is no evidence that currently available asthma and allergy treatments, including antihistamines, corticosteroids, and bronchodilators, increase the risk of severe disease from COVID-19. Most countries affected by COVID-19 have opted for nationwide confinement, which means that communication with the primary clinician is often performed by telemedicine. Optimal disease control of allergic, asthmatic, and immunodeficient children should be sought according to usual treatment guidelines. This statement of the EAACI Section on Pediatrics puts forward six recommendations for the management of childhood allergies and immunodeficiencies based on six underlying facts and existing evidence.

Allergy and Clinical Immunology Department Hospital Sant Joan de Déu Universitat de Barcelona Spain

Allergy Department Hospital Infantil Universitario Niño Jesus Madrid Spain

Child Health Department University of Ioannina School of Medicine Ioannina Greece

Department of Immunology 2nd Medical Faculty Charles University and Motol University Hospital Prague Czech Republic

Department of Paediatrics and Paediatric Infectious Diseases Institute of Child's Health Sechenov 1st Moscow State Medical University Moscow Russia

Department of Pediatric Allergy and Immunology Istanbul Health Sciences University Kanuni Sultan Suleyman Research and Training Hospital Istanbul Turkey

Department of Women and Children's Health Children's Allergy Service Evelina Children's Hospital Guy's and St Thomas' Hospital NHS Foundation Trust Paediatric Allergy Group School of Life Course Sciences King's College London London UK

Hacettepe University School of Medicine Ankara Turkey

Institute of Pathophysiology and Allergy Research Center of Pathophysiology Infectiology and Immunology Medical University of Vienna Vienna Austria

Pediatric Allergology Unit Department of Pediatric Medicine Bambino Gesù Children's research Hospital Rome Italy

Pediatric Allergology Unit Department of Pediatric Medicine S Pietro Hospital Fatebenefratelli Rome Italy

Pediatric Allergy Unit Department of Woman Child and Adolescent University Hospitals of Geneva Geneva Switzerland

Section of Inflammation Repair and Development National Heart and Lung Institute Imperial College London UK

Zobrazit více v PubMed

Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727‐733. PubMed PMC

Genomic epidemiology of novel coronavirus ‐ Global subsampling. Available at: https://nextstrain.org/ncov/global. Accessed April 18, 2020.

Ludvigsson JF. Systematic review of COVID‐19 in children shows milder cases and a better prognosis than adults. Acta Paediatr. 2020. 10.1111/apa.15270 PubMed DOI PMC

Bauchner H, Golub RM, Zylke J. Editorial concern—Possible reporting of the same patients with COVID‐19 in different reports. JAMA. 2020;323:1256‐1256. PubMed

Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID‐19) outbreak in China: Summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA. 2020;323(13):1239. PubMed

Lu X, Zhang L, Du H, et al. SARS‐CoV‐2 infection in children. N Engl J Med. 2020;382(17):1663‐1665 PubMed PMC

Liu W, Zhang Q, Chen J, et al. Detection of Covid‐19 in Children in Early January 2020 in Wuhan, China. N Engl J Med. 2020;382:1370‐1371. PubMed PMC

Dong Y, Mo X, Hu Y, et al. Epidemiological characteristics of 2143 pediatric patients with 2019 Coronavirus disease in China. Pediatrics. 2020;145 e20200702. 10.1542/peds.2020-0702 PubMed DOI

Cruz A, Zeichner S. COVID‐19 in children: Initial characterization of the pediatric disease. Pediatrics. 2020;145 e20200834. 10.1542/peds.2020-0834 PubMed DOI

CDCMMWR . Coronavirus Disease 2019 in Children — United States, February 12–April 2, 2020. MMWR Morb Mortal Wkly Rep. 2019;2020:69. 10.15585/mmwr.mm6914e4 PubMed DOI PMC

Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet. 2020;395:497‐506. PubMed PMC

Lee P‐I, Hu Y‐L, Chen P‐Y, et al. Are children less susceptible to COVID‐19? J Microbiol Immunol Infect. 2020. 10.1016/j.jmii.2020.02.011 PubMed DOI PMC

Kam Y‐W, Okumura Y, Kido H, et al. Cleavage of the SARS Coronavirus spike glycoprotein by airway proteases enhances virus entry into human bronchial epithelial cells in vitro. PLoS ONE. 2009;4:e7870. PubMed PMC

Brodin P. Why is COVID‐19 so mild in children? Acta Paediatr. 2020. 10.1111/apa.15271 PubMed DOI

Nickbakhsh S, Mair C, Matthews L, et al. Virus–virus interactions impact the population dynamics of influenza and the common cold. Proc Natl Acad Sci. 2019;116:27142‐27150. PubMed PMC

Ng PC, Lam CWK, Li AM, et al. Inflammatory cytokine profile in children with severe acute respiratory syndrome. Pediatrics. 2004;113:e7‐e14. PubMed

Kam K, Yung CF, Cui L, et al. A well infant with coronavirus disease 2019 with high viral load. Clin Infect Dis. 2020. 10.1093/cid/ciaa201 PubMed DOI PMC

Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID‐19 in Wuhan, China: a retrospective cohort study. The Lancet. 2020;395:1054‐1062. PubMed PMC

CDC . Coronavirus Disease 2019 (COVID‐19). Cent Dis Control Prev. 2020. Available at: https://www.cdc.gov/coronavirus/2019‐ncov/need‐extra‐precautions/asthma.html. Accessed April 2, 2020.

Most Recent National Asthma Data . Centers for Disease Control and Prevention (CDC). 2020. Available at: https://www.cdc.gov/asthma/most_recent_national_asthma_data.htm. Accessed April 19, 2020.

EAACI position paper on care during COVID‐19. Allergy. 2020: in progress.

Zhang J‐J, Dong X, Cao Y‐Y, et al. Clinical characteristics of 140 patients infected with SARS‐CoV‐2 in Wuhan, China. Allergy. 2020. 10.1111/all.14238 PubMed DOI

Russell CD, Millar JE, Baillie JK. Clinical evidence does not support corticosteroid treatment for 2019‐nCoV lung injury. The Lancet. 2020;395:473‐475. PubMed PMC

Clinical management of severe acute respiratory infection when COVID‐19 is suspected. Available at: https://www.who.int/publications‐detail/clinical‐management‐of‐severe‐acute‐respiratory‐infection‐when‐novel‐coronavirus‐(ncov)‐infection‐is‐suspected. Accessed April 2, 2020.

Corneli HM, Zorc JJ, Mahajan P, et al. A multicenter, randomized, controlled trial of dexamethasone for bronchiolitis. N Engl J Med. 2007;357:331‐339. PubMed

Villar J, Ferrando C, Martínez D, et al. Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial. Lancet Respir Med. 2020;8:267‐276. PubMed

Siddiqi HK, Mehra MR. COVID‐19 illness in native and immunosuppressed states: A Clinical‐Therapeutic Staging Proposal. J Heart Lung Transplant. 2020;39:405–407. PubMed PMC

COVID‐19: GINA Answers to Frequently Asked Questions on asthma management. Glob Initiat Asthma ‐ GINA. 2020. Available at: https://ginasthma.org/covid‐19‐gina‐answers‐to‐frequently‐asked‐questions‐on‐asthma‐management/. Accessed April 11, 2020.

BTS Advice for Healthcare Professionals treating patients with asthma. Available at: https://www.brit‐thoracic.org.uk/document‐library/quality‐improvement/covid‐19/bts‐advice‐for‐healthcare‐professionals‐treating‐patients‐with‐asthma/. Accessed April 5, 2020.

Cazeiro C, Silva C, Mayer S, et al. Inhaled corticosteroids and respiratory infections in children with asthma: A Meta‐analysis. Pediatrics. 2017;139:e20163271. 10.1542/peds.2016-3271 PubMed DOI

Kaiser SV, Huynh T, Bacharier LB, et al. Preventing exacerbations in preschoolers with recurrent wheeze: A Meta‐analysis. Pediatrics. 2016;137:e20154496. 10.1542/peds.2015-4496 PubMed DOI

Vultaggio A. Considerations on biologicals for patients with allergic disease in times of the COVID‐19 pandemic. Allergy. 2020; in press. PubMed PMC

Joint statement on the current epidemics of new Coronavirus. Available at: https://www.ceredih.fr/uploads/COVID19_WORLDWIDE_Joint_Statement_20200311_1200CET_FINAL.pdf. Accessed April 7, 2020.

COVID‐19 in PID (retrospective survey). Available at: https://www.surveymonkey.com/r/67RBPNZ. Accessed April 7, 2020.

Bloch EM, Shoham S, Casadevall A, et al. Deployment of convalescent plasma for the prevention and treatment of COVID‐19. J Clin Invest. 2020. 10.1172/JCI138745 PubMed DOI PMC

Shaker MS, Oppenheimer J, Grayson M, et al. COVID‐19: Pandemic contingency planning for the allergy and immunology clinic. J Allergy Clin Immunol Pract. 2020. 10.1016/j.jaip.2020.03.012 PubMed DOI PMC

Broxmeyer HE, Parker GC. Impact of COVID‐19 and future emerging viruses on hematopoietic cell transplantation and other cellular therapies. Stem Cells Dev. 2020. 10.1089/scd.2020.0064 PubMed DOI PMC

Zheng M, Gao Y, Wang G, et al. Functional exhaustion of antiviral lymphocytes in COVID‐19 patients. Cell Mol Immunol. 2020;17:533‐535. PubMed PMC

Ahmadpoor P, Rostaing L. Why the immune system fails to mount an adaptive immune response to a COVID ‐19 infection. Transpl Int Off J Eur Soc Organ Transplant. 2020. 10.1111/tri.13611 PubMed DOI

Chen G, Wu D, Guo W, et al. Clinical and immunologic features in severe and moderate Coronavirus Disease 2019. J Clin Invest. 2020. 10.1172/JCI137244 PubMed DOI PMC

The COVID Human Genetic Effort. COVID Hum Genet. EFFORT. Available at: https://www.covidhge.com. Accessed April 7, 2020.

Cluver L, Lachman JM, Sherr L, et al. Parenting in a time of COVID‐19. The Lancet. 2020;395:e64. PubMed PMC

Global Initiative for Asthma. Glob Initiat. Asthma ‐ GINA. Available at: https://ginasthma.org/. Accessed April 2, 2020.

Shielding advice for very high‐risk groups. Asthma UK. Available at: https://www.asthma.org.uk/advice/triggers/coronavirus‐covid‐19/#Shielding. Accessed April 5, 2020.

Elliott T, Shih J, Dinakar C, et al. American College of Allergy, Asthma & Immunology Position Paper on the Use of Telemedicine for Allergists. Ann Allergy Asthma Immunol. 2017;119:512‐517. PubMed

Najít záznam

Citační ukazatele

Nahrávání dat ...

Možnosti archivace

Nahrávání dat ...