A surface-enhanced Raman scattering-chiral anisotropy (SERS-ChA) effect is reported that combines chiral discrimination and surface Raman scattering enhancement on chiral nanostructured Au films (CNAFs) equipped in the normal Raman scattering Spectrometer. The CNAFs provided remarkably higher enhancement factors of Raman scattering (EFs) for particular enantiomers, and the SERS intensity was proportional to the enantiomeric excesses (ee) values. Except for molecules with mesomeric species, all of the tested enantiomers exhibited high SERS-ChA asymmetry factors (g), ranging between 1.34 and 1.99 regardless of polarities, sizes, chromophores, concentrations and ee. The effect might be attributed to selective resonance coupling between the induced electric and magnetic dipoles associated with enantiomers and chiral plasmonic modes of CNAFs.

College of Chemistry and Chemical Engineering Xiamen University Xiamen 361005 P R China

Department of Chemical Engineering and Biointerfaces Institute University of Michigan Ann Arbor MI 48019 USA

Institute of Organic Chemistry and Biochemistry Czech Academy of Sciences Fleminovo náměstí 2 16610 Prague Czech Republic

School of Chemical Science and Engineering Tongji University 1239 Siping Road Shanghai 200092 P R China

School of Chemistry and Chemical Engineering State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong University 800 Dongchuan Road Shanghai 200240 P R China

Synfuels China Technology Co Ltd Beijing 101407 P R China

See more in PubMed

J. Shen, Y. Okamoto, Chem. Rev. 2016, 116, 1094-1138;

T. D. James, K. Sandanayake, S. Shinkai, Nature 1995, 374, 345-347;

D. Patterson, M. Schnell, J. M. Doyle, Nature 2013, 497, 475-478;

K. Banerjee-Ghosh, O. Ben Dor, F. Tassinari, E. Capua, S. Yochelis, A. Capua, S. H. Yang, S. S. P. Parkin, S. Sarkar, L. Kronik, L. T. Baczewski, R. Naaman, Y. Paltiel, Science 2018, 360, 1331-1334;

S. Dutta, A. J. Gellman, Chem. Soc. Rev. 2017, 46, 7787-7839;

P. Lesot, C. Aroulanda, H. Zimmermann, Z. Luz, Chem. Soc. Rev. 2015, 44, 2330-2375.

L. D. Barron, Molecular Light Scattering and Optical Activity, Cambridge University Press, Cambridge, 1982;

N. Berova, L. Di Bari, G. Pescitelli, Chem. Soc. Rev. 2007, 36, 914-931;

L. Yang, C. S. Kwan, L. L. Zhang, X. H. Li, Y. Han, K. C. F. Leung, Y. G. Yang, Z. F. Huang, Adv. Funct. Mater. 2019, 29, 8;

B. T. Thole, P. Carra, F. Sette, G. Vanderlaan, Phys. Rev. Lett. 1992, 68, 1943-1946;

L. A. Nafie, Vibrational Optical Activity: Principles and Applications, Blackwell Science Publ, Oxford, 2011;

N. Berova, K. Nakanishi, R. W. Woody, Circular dichroism : principles and applications, Wiley-VCH, Weinheim, 2000;

N. Bouldi, N. J. Vollmers, C. G. Delpy-Laplanche, Y. Joly, A. Juhin, P. Sainctavit, C. Brouder, M. Calandra, L. Paulatto, F. Mauri, U. Gerstmann, Phys. Rev. B 2017, 96, 12.

D. Sofikitis, L. Bougas, G. E. Katsoprinakis, A. K. Spiliotis, B. Loppinet, T. P. Rakitzis, Nature 2014, 514, 76-79;

S. Beaulieu, A. Comby, D. Descamps, B. Fabre, G. A. Garcia, R. Geneaux, A. G. Harvey, F. Legare, Z. Masin, L. Nahon, A. F. Ordonez, S. Petit, B. Pons, Y. Mairesse, O. Smirnova, V. Blanchet, Nat. Phys. 2018, 14, 484-489.

K. Kneipp, Y. Wang, H. Kneipp, L. T. Perelman, I. Itzkan, R. Dasari, M. S. Feld, Phys. Rev. Lett. 1997, 78, 1667-1670;

S. Y. Ding, J. Yi, J. F. Li, B. Ren, D. Y. Wu, R. Panneerselvam, Z. Q. Tian, Nat. Rev. Mater. 2016, 1, 16;

M. Fleischmann, P. J. Hendra, A. J. McQuillan, Chem. Phys. Lett. 1974, 26, 163-166.

M. Moskovits, Rev. Mod. Phys. 1985, 57, 783-826;

E. C. Le Ru, P. G. Etchegoin, Principles of Surface-Enhanced Raman Spectroscopy, Elsevier, Amsterdam, 2009.

S. Abdali, E. W. Blanch, Chem. Soc. Rev. 2008, 37, 980-992.

L. D. Barron, A. D. Buckingham, Annu. Rev. Phys. Chem. 1975, 26, 381-396.

J. He, Y. Wang, Y. Feng, X. Qi, Z. Zeng, Q. Liu, W. S. Teo, C. L. Gan, H. Zhang, H. Chen, ACS Nano 2013, 7, 2733-2740.

Y. H. Zhu, J. T. He, C. Shang, X. H. Miao, J. F. Huang, Z. P. Liu, H. Y. Chen, Y. Han, J. Am. Chem. Soc. 2014, 136, 12746-12752;

A. H. Boerdijk, Philips Res. Rep. 1952, 7, 303-313;

J. Yan, W. C. Fang, J. Y. Kim, J. Lu, P. Kumar, Z. Z. Mu, X. C. Wu, X. M. Mao, N. A. Kotov, Chem. Mater. 2020, 32, 476-488.

P. Oleynikov, Cryst. Res. Technol. 2011, 46, 569-579.

J. Zhou, J. An, B. Tang, S. P. Xu, Y. X. Cao, B. Zhao, W. Q. Xu, J. J. Chang, J. R. Lombardi, Langmuir 2008, 24, 10407-10413;

C. G. Khoury, T. Vo-Dinh, J. Phys. Chem. C 2008, 112, 18849-18859.

M. Yang, R. Alvarez-Puebla, H. S. Kim, P. Aldeanueva-Potel, L. M. Liz-Marzan, N. A. Kotov, Nano Lett. 2010, 10, 4013-4019.

Bisignate Surface-Enhanced Raman Optical Activity with Analyte-Capped Colloids

Toward a New Era of SERS and TERS at the Nanometer Scale: From Fundamentals to Innovative Applications

Two Spectroscopies in One: Interference of Circular Dichroism and Raman Optical Activity