Potential approaches for the pricing of cancer medicines across Europe to enhance the sustainability of healthcare systems and the implications

. 2021 Aug ; 21 (4) : 527-540. [epub] 20210311

Jazyk angličtina Země Velká Británie, Anglie Médium print-electronic

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/pmid33535841

Introduction: There are growing concerns among European health authorities regarding increasing prices for new cancer medicines, prices not necessarily linked to health gain and the implications for the sustainability of their healthcare systems.Areas covered: Narrative discussion principally among payers and their advisers regarding potential approaches to the pricing of new cancer medicines.Expert opinion: A number of potential pricing approaches are discussed including minimum effectiveness levels for new cancer medicines, managed entry agreements, multicriteria decision analyses (MCDAs), differential/tiered pricing, fair pricing models, amortization models as well as de-linkage models. We are likely to see a growth in alternative pricing deliberations in view of ongoing challenges. These include the considerable number of new oncology medicines in development including new gene therapies, new oncology medicines being launched with uncertainty regarding their value, and continued high prices coupled with the extent of confidential discounts for reimbursement. However, balanced against the need for new cancer medicines. This will lead to greater scrutiny over the prices of patent oncology medicines as more standard medicines lose their patent, calls for greater transparency as well as new models including amortization models. We will be monitoring these developments.

Centre for Health Economics Research and Evaluation University of Technology Sydney Broadway Sydney NSW

College of Pharmacy Ewha Woman's University Seoul South Korea

Data and Knowledge Integration Center for Health Salvador Bahia Brazil

Department for Health Evidence Radboud University Medical Center Nijmegen The Netherlands

Department of Medical Biophysics Faculty of Medicine in Hradec Králové Charles University Hradec Králové Czech Republic

Department of Medicine Lagos State University Teaching Hospital Ikeja Lagos Nigeria

Department of Nutrition and Drug Research Faculty of Health Sciences Jagiellonian University Medical College Krakow Poland

Department of Pathology Forensic Medicine and Pharmacology Institute of Biomedical Sciences Faculty of Medicine Vilnius University Vilnius Lithuania

Department of Pharmaceutical Affairs Federation of Social Insurances Vienna Austria

Department of Pharmaceutical and Pharmacological Sciences KU Leuven Belgium

Department of Pharmacology College of Pharmacy Hawler Medical University Erbil Iraq

Department of Pharmacology Therapeutics and Toxicology Lagos State University College of Medicine Ikeja Lagos Nigeria

Department of Pharmacology Therapeutics and Toxicology Universitat Autònoma De Barcelona Barcelona Spain

Department of Pharmacy Faculty of Medicine University of Medicine Tirana Albania

Department of Pharmacy Ministry of Health of the Republic of Lithuania Vilnius Lithuania

Division of Biology and Public Health Mokwon University Daejeon Korea

Division of Clinical Pharmacology Karolinska Institute Karolinska University Hospital Huddinge Stockholm Sweden

Division of Pharmacoepidemiology Strathclyde Institute of Pharmacy and Biomedical Sciences University of Strathclyde Glasgow UK

Division of Public Health Pharmacy and Management School of Pharmacy Sefako Makgatho Health Sciences University Pretoria South Africa

Drug Department Catalan Health Service Catalan Health Service Barcelona Spain

Faculty of Health and Life Sciences Liverpool UK

Faculty of Health Studies Rijeka Croatia

Faculty of Medicine Department of Social Pharmacy University of Banja Luka Banja Luka Republic of Srpska Bosnia and Herzegovina

Faculty of Medicine Public Health and Management Department Carol Davila University of Medicine and Pharmacy Bucharest Bucharest Romania

Faculty of Medicine Slovak Medical University in Bratislava Bratislava Slovakia

Faculty of Pharmacy Department of Social Pharmacy and Pharmacoeconomics Medical University of Sofia Sofia Bulgaria

Faculty of Pharmacy Postgraduate Program in Medicines and Pharmaceutical Services Federal University of Minas Gerais Belo Horizonte Minas Gerais Brazil

Faculty of Pharmacy UBT Higher Education Institution Prishtina Kosovo

Health Data Science Institute of Population Health Liverpool Canadian Organization for Rare Disorders Toronto Ontario Canada

Health Data Science Institute of Population Health Liverpool Reviews and Implementation Group Whelan Building University of Liverpool Liverpool UK

Health Insurance Institute Ljubljana Slovenia

HTA Consulting Cracow Poland

Independent Consumer Advocate Brunswick Victoria Australia

Independent Researcher Boston MA United States

Institute of Translational Medicine University of Liverpool UK

Istituto Di Ricerche Farmacologiche 'Mario Negri' IRCCS Milan Italy

National Health Care Institute XH Diemen Netherlands

NHS Lothian Edinburgh UK

Pharmaceutical Drug Department Azienda Sanitaria Locale of Verona Verona Italy

Public Health Scotland Edinburgh UK

QC Medica Sim Balk Lane York UK

Reviews and Health Technology Assessments Norwegian Institute of Public Health Oslo Norway

School of National and Kapodistrian University of Athens Athens Greece

School of Pharmaceutical Sciences Universiti Sains Malaysia Penang Malaysia

State Agency of Medicines Tartu Estonia

Statistics Department Bruxelles Belgium

SUS Collaborating Centre for Technology Assessment and Excellence in Health Belo Horizonte Minas Gerais Brazil

University of Medicine Tirana Albania

Wissenschaftliches Institut Der AOK Berlin Germany

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