AIM: Understanding cardiac electronic device infective endocarditis epidemiology is essential for the management of this serious complication. Only monocentric and limited data have been published regarding patients in the Czech republic so far. The aim of this study was to describe the current profile, microbiology and clinical characteristics of this population. PATIENTS AND METHODS: National data from the prospective ESC-EORP EURO-ENDO registry were collected. 57 consecutive patients with a diagnosis of cardiac device-related infective endocarditis (CDRIE) from 11 Czech centres were included. RESULTS: Staphylococcus spp. was responsible for 43.9% of isolates, whereas Culture negative endocarditis was documented in 26.3% episodes. The most frequent complications under therapy were acute renal failure (17.5%), septic shock and heart failure (both 10.5%). Extraction of device was performed in 75.4% of all patients, and the 1-year mortality was 22.5%. CONCLUSIONS: The high proportion of culture-negative endocarditis is alarming and warrants further investigation. Cardiac device related infective endocarditis is a serious complication with a high 1-year mortality in a highly polymorbid spectrum of patients.

1st Department of Internal Medicine Cardioangiology Faculty Hospital in Hradec Kralove Czech Republic

2nd Department of Internal Cardiovascular Medicine 1st Faculty of Medicine Charles University and General University Hospital Prague Czech Republic

Cardiocenter 3rd Faculty of Medicine Charles University Prague Czech Republic

Cardiovascular Center for Adults Tomas Bata Regional Hospital Zlin Czech Republic

Center for Cardiovascular Prevention 1st Faculty of Medicine Charles University and Thomayer Hospital Prague Czech Republic

Department of Cardiac Surgery Na Homolce Hospital Prague Czech Republic

Department of Cardiology 2nd Faculty of Medicine Charles University and University Hospital Motol Prague Czech Republic

Department of Cardiology IKEM Prague Czech Republic

Department of Cardiology Regional Hospital Liberec Czech Republic

Department of Cardiology University Hospital Pilsen and Faculty of Medicine in Pilsen Charles University Pilsen Czech Republic

Department of Cardiovascular Diseases University Hospital in Ostrava Czech Republic

Department of Internal Medicine 1 Cardiology University Hospital Olomouc Czech Republic

Department of Internal Medicine and Cardiology University Hospital Brno Czech Republic

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