Type-2-diabetes mellitus (T2DM) is a global problem of medical, social and economic consequences. Physical activity is a vital therapy in patients with T2DM, but some of them cannot exercise for various reasons. The purpose of our pilot study was to determine whether a combination of neuromuscular electrostimulation (NMES) and insulin therapy could improve the management of T2DM patients with hemiplegia caused by an ischemic stroke. Fifteen immobile patients with T2DM on insulin therapy were enrolled in the study. NMES was applied to their lower limbs for 60 min, 5 days a week, over a period of 12 weeks. The intervention caused statistically significant reductions in the blood concentrations of glycated hemoglobin, total cholesterol and low-density cholesterol in the participants. Furthermore, systolic and diastolic blood pressure levels were significantly lower. More randomized clinical trials are needed to accurately measure the effect of NMES on T2DM treatment and to determine whether it can be an alternative for physical activity for immobile patients with T2DM.

Department of Medicine and Dentistry in Zabrze The Silesian Medical University 2 Traugutta Str 40 055 Katowice Poland

Department of Neurology Silesian Hospital 4 Bielska Str 43 400 Cieszyn Poland

Doctoral School The Jerzy Kukuczka Academy of Physical Education 72A Mikolowska Str 40 065 Katowice Poland

Institute of Physiotherapy and Health Sciences The Jerzy Kukuczka Academy of Physical Education 72A Mikolowska Str 40 065 Katowice Poland

Laboratory Physical Training Adaptation Faculty of Physical Education and Sport Charles University Ovocny trh 5 11636 Prague Czech Republic

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