Global, regional, and national burden of mortality associated with non-optimal ambient temperatures from 2000 to 2019: a three-stage modelling study

. 2021 Jul ; 5 (7) : e415-e425.

Jazyk angličtina Země Nizozemsko Médium print

Typ dokumentu časopisecké články, Research Support, N.I.H., Extramural, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/pmid34245712

Grantová podpora
P30 ES019776 NIEHS NIH HHS - United States
MR/R013349/1 Medical Research Council - United Kingdom

Odkazy

PubMed 34245712
DOI 10.1016/s2542-5196(21)00081-4
PII: S2542-5196(21)00081-4
Knihovny.cz E-zdroje

BACKGROUND: Exposure to cold or hot temperatures is associated with premature deaths. We aimed to evaluate the global, regional, and national mortality burden associated with non-optimal ambient temperatures. METHODS: In this modelling study, we collected time-series data on mortality and ambient temperatures from 750 locations in 43 countries and five meta-predictors at a grid size of 0·5° × 0·5° across the globe. A three-stage analysis strategy was used. First, the temperature-mortality association was fitted for each location by use of a time-series regression. Second, a multivariate meta-regression model was built between location-specific estimates and meta-predictors. Finally, the grid-specific temperature-mortality association between 2000 and 2019 was predicted by use of the fitted meta-regression and the grid-specific meta-predictors. Excess deaths due to non-optimal temperatures, the ratio between annual excess deaths and all deaths of a year (the excess death ratio), and the death rate per 100 000 residents were then calculated for each grid across the world. Grids were divided according to regional groupings of the UN Statistics Division. FINDINGS: Globally, 5 083 173 deaths (95% empirical CI [eCI] 4 087 967-5 965 520) were associated with non-optimal temperatures per year, accounting for 9·43% (95% eCI 7·58-11·07) of all deaths (8·52% [6·19-10·47] were cold-related and 0·91% [0·56-1·36] were heat-related). There were 74 temperature-related excess deaths per 100 000 residents (95% eCI 60-87). The mortality burden varied geographically. Of all excess deaths, 2 617 322 (51·49%) occurred in Asia. Eastern Europe had the highest heat-related excess death rate and Sub-Saharan Africa had the highest cold-related excess death rate. From 2000-03 to 2016-19, the global cold-related excess death ratio changed by -0·51 percentage points (95% eCI -0·61 to -0·42) and the global heat-related excess death ratio increased by 0·21 percentage points (0·13-0·31), leading to a net reduction in the overall ratio. The largest decline in overall excess death ratio occurred in South-eastern Asia, whereas excess death ratio fluctuated in Southern Asia and Europe. INTERPRETATION: Non-optimal temperatures are associated with a substantial mortality burden, which varies spatiotemporally. Our findings will benefit international, national, and local communities in developing preparedness and prevention strategies to reduce weather-related impacts immediately and under climate change scenarios. FUNDING: Australian Research Council and the Australian National Health and Medical Research Council.

Center for Environmental and Respiratory Health Research and Biocenter Oulu University of Oulu Oulu Finland

Center for Environmental and Respiratory Health Research and Biocenter Oulu University of Oulu Oulu Finland; Finnish Meteorological Institute Helsinki Finland

Centre for Sustainability and Environmental Health National Institute for Public Health and the Environment Bilthoven Netherlands

CIBER of Epidemiology and Public Health Madrid Spain; Department of Geography University of Santiago de Compostela Santiago de Compostela Spain

Department of Earth Sciences University of Turin Turin Italy

Department of Environmental and Occupational Health Santé Publique France French National Public Health Agency Saint Maurice France

Department of Environmental Health Faculty of Public Health University of Medicine and Pharmacy at Ho Chi Minh City Ho Chi Minh City Vietnam

Department of Environmental Health Harvard T H Chan School of Public Health Harvard University Boston MA USA

Department of Environmental Health Instituto Nacional de Saúde Dr Ricardo Jorge Porto Portugal; EPIUnit Instituto de Saúde Pública Universidade do Porto Porto Portugal

Department of Environmental Health National Institute of Public Health Cuernavaca Morelos Mexico

Department of Environmental Health School of Public Health Fudan University Shanghai China

Department of Environmental Health University of São Paulo São Paulo Brazil

Department of Epidemiology and Preventive Medicine School of Public Health and Preventive Medicine Monash University Melbourne VIC Australia; Climate Air Quality Research Unit School of Public Health and Preventive Medicine Monash University Melbourne VIC Australia

Department of Epidemiology and Public Health Swiss Tropical and Public Health Institute Basel Switzerland; University of Basel Basel Switzerland

Department of Epidemiology Instituto Nacional de Saúde Dr Ricardo Jorge Porto Portugal; Centro de Investigação em Saúde Pública Escola Nacional de Saúde Pública Universidade NOVA de Lisboa Lisbon Portugal

Department of Epidemiology Lazio Regional Health Service Rome Italy

Department of Epidemiology School of Public Health Cheeloo College of Medicine Shandong University Jinan China; Department of Epidemiology and Preventive Medicine School of Public Health and Preventive Medicine Monash University Melbourne VIC Australia

Department of Global Health Policy Graduate School of Medicine The University of Tokyo Tokyo Japan

Department of Hygiene Epidemiology and Medical Statistics National and Kapodistrian University of Athens Athens Greece

Department of Hygiene Epidemiology and Medical Statistics National and Kapodistrian University of Athens Athens Greece; School of Population Health and Environmental Sciences King's College London London UK

Department of Pathology Faculty of Medicine University of São Paulo São Paulo Brazil

Department of Public Health and Clinical Medicine Umeå University Umeå Sweden

Department of Public Health Environments and Society London School of Hygiene and Tropical Medicine London UK

Department of Public Health Environments and Society London School of Hygiene and Tropical Medicine London UK; Centre for Statistical Methodology London School of Hygiene and Tropical Medicine London UK; Centre on Climate Change and Planetary Health London School of Hygiene and Tropical Medicine London UK

Department of Public Health Environments and Society London School of Hygiene and Tropical Medicine London UK; Department of Statistics Computer Science and Applications G Parenti University of Florence Florence Italy

Department of Public Health Universidad de los Andes Santiago Chile

Department of Quantitative Methods School of Medicine University of the Republic Montevideo Uruguay

Department of Statistics and Computational Research Universitat de València València Spain; CIBER of Epidemiology and Public Health Madrid Spain

Faculty of Geography and Environmental Sciences Hakim Sabzevari University Sabzevar Iran

Faculty of Geography Babeş Bolyai University Cluj Napoca Romania

Faculty of Health and Sport Sciences University of Tsukuba Tsukuba Japan

Gangarosa Department of Environmental Health Rollins School of Public Health Emory University Atlanta GA USA

Graduate School of Public Health Seoul National University Seoul South Korea

Health Innovation Lab Institute of Tropical Medicine Alexander von Humboldt Universidad Peruana Cayetano Heredia Lima Peru; Division of Infectious Diseases Department of Medicine University of California San Diego CA USA

Institute of Atmospheric Physics Czech Academy of Sciences Prague Czech Republic; Faculty of Environmental Sciences Czech University of Life Sciences Prague Czech Republic

Institute of Environment Health and Societies Brunel University London London UK

Institute of Environmental Assessment and Water Research Spanish Council for Scientific Research Barcelona Spain; School of Tropical Medicine and Global Health Nagasaki University Nagasaki Japan

Institute of Epidemiology Helmholtz Zentrum München German Research Center for Environmental Health Neuherberg Germany

Institute of Family Medicine and Public Health University of Tartu Tartu Estonia

Institute of Social and Preventive Medicine University of Bern Bern Switzerland; Oeschger Center for Climate Change Research University of Bern Bern Switzerland

Instituto de Investigaciones Gino Germani Facultad de Ciencias Sociales Universidad de Buenos Aires Buenos Aires Argentina

Laboratory of Management in Science and Public Health National Agency for Public Health of the Ministry of Health Chisinau Moldova

National Institute of Environmental Health Science National Health Research Institutes Zhunan Taiwan

National Institute of Environmental Health Science National Health Research Institutes Zhunan Taiwan; Environmental and Occupational Medicine NTU College of Medicine and NTU Hospital National Taiwan University Taipei Taiwan; Institute of Environmental and Occupational Health Sciences NTU College of Public Health National Taiwan University Taipei Taiwan

Norwegian institute of Public Health Oslo Norway

Potsdam Institute for Climate Impact Research Potsdam Germany; Department of Physical Chemical and Natural Systems Universidad Pablo de Olavide Sevilla Spain

School of Epidemiology and Public Health Faculty of Medicine University of Ottawa Ottawa ON Canada; Air Health Science Division Health Canada Ottawa ON Canada

School of Physics Technological University Dublin Dublin Ireland

School of the Environment Yale University New Haven CT USA

School of Tropical Medicine and Global Health Nagasaki University Nagasaki Japan

Shanghai Children's Medical Centre Shanghai Jiao Tong University Shanghai China; School of Public Health Institute of Environment and Population Health Anhui Medical University Hefei China; Center for Global Health Nanjing Medical University Nanjing China; School of Public Health and Social Work Queensland University of Technology Brisbane QLD Australia

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