Recent Advances in Pathology: the 2022 Annual Review Issue of The Journal of Pathology

. 2022 Jul ; 257 (4) : 379-382.

Jazyk angličtina Země Anglie, Velká Británie Médium print

Typ dokumentu úvodníky, úvodní články

Perzistentní odkaz   https://www.medvik.cz/link/pmid35635736

The 2022 Annual Review Issue of The Journal of Pathology, Recent Advances in Pathology, contains 15 invited reviews on research areas of growing importance in pathology. This year, the articles include those that focus on digital pathology, employing modern imaging techniques and software to enable improved diagnostic and research applications to study human diseases. This subject area includes the ability to identify specific genetic alterations through the morphological changes they induce, as well as integrating digital and computational pathology with 'omics technologies. Other reviews in this issue include an updated evaluation of mutational patterns (mutation signatures) in cancer, the applications of lineage tracing in human tissues, and single cell sequencing technologies to uncover tumour evolution and tumour heterogeneity. The tissue microenvironment is covered in reviews specifically dealing with proteolytic control of epidermal differentiation, cancer-associated fibroblasts, field cancerisation, and host factors that determine tumour immunity. All of the reviews contained in this issue are the work of invited experts selected to discuss the considerable recent progress in their respective fields and are freely available online (https://onlinelibrary.wiley.com/journal/10969896). © 2022 The Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

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Zarella MD, Alvarez KR. High throughput whole-slide scanning to enable large-scale data repository building. J Pathol 2022; 257: 383-390.

Bankhead P. Developing image analysis methods for digital pathology. J Pathol 2022; 257: 391-402.

Kramer CJH, Vreeswijk MPG, Thijssen B, et al. Beyond the snapshot: optimizing prognostication and prediction by moving from fixed to functional multidimensional cancer pathology. J Pathol 2022; 257: 403-412.

Viswanthan VS, Toro P, Corredor G, et al. The state of the art for artificial intelligence in lung digital pathology. J Pathol 2022; 257: 413-429.

Cifci D, Foersch S, Kather JN. Artificial intelligence to identify genetic alterations in conventional histopathology. J Pathol 2022; 257: 430-444.

Dent A, Diamandis P. Integrating computational pathology and proteomics to address tumor heterogeneity. J Pathol 2022; 257: 445-453.

Steele CD, Pillay N, Alexandrov LB. An overview of mutational and copy number signatures in human cancer. J Pathol 2022; 257: 454-465.

Bowes A, Tarabichi M, Pillay N, et al. Leveraging single-cell sequencing to unravel intratumour heterogeneity and tumour evolution in human cancers. J Pathol 2022; 257: 466-478.

Hamdan A, Ewing A. Unravelling the tumour genome: the evolutionary and clinical impacts of structural variants in tumourigenesis. J Pathol 2022; 257: 479-493.

Carraro G, Stripp BR. Insights gained in the pathology of lung disease through single cell transcriptomics. J Pathol 2022; 257: 494-500.

Gabbutt C, Wright NA, Baker AM, et al. Lineage tracing in human tissues. J Pathol 2022; 257: 501-512.

Gunjur A, Manrique-Rincón AJ, Klein O, et al. ‘Know thyself’ - host factors influencing cancer response to immune checkpoint inhibitors. J Pathol 2022; 257: 513-525.

Menezes S, Okail MH, Jalil SMA, et al. Cancer-associated fibroblasts in pancreatic cancer: new subtypes, new markers, new targets. J Pathol 2022; 257: 526-544.

Sotiropoulou G, Zingkou E, Pampalakis G. Reconstructing the epidermal proteolytic cascades in health and disease. J Pathol 2022; 257: 545-560.

Gadaleta E, Thorn GJ, Ross-Adams H, et al. Field cancerization in breast cancer. J Pathol 2022; 257: 561-574.

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