Skin manifestations of pancreatic diseases
Jazyk angličtina Země Česko Médium print-electronic
Typ dokumentu časopisecké články, přehledy
PubMed
35938387
DOI
10.5507/bp.2022.035
Knihovny.cz E-zdroje
- Klíčová slova
- acanthosis nigricans, acute pancreatitis, chronic pancreatitis, livedo reticularis, necrolytic migratory erythema, pancreatic cancer, pancreatic panniculitis, skin lesions,
- MeSH
- akutní nemoc MeSH
- kožní nemoci * etiologie MeSH
- kůže MeSH
- lidé MeSH
- nádory slinivky břišní * komplikace MeSH
- nemoci slinivky břišní * komplikace patologie MeSH
- pankreatitida * etiologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
Although symptoms of pancreatic diseases such as pancreatitis, acute and chronic and, carcinoma of the pancreas are mainly gastrointestinal in nature, the extra-pancreatic symptoms are also important. These include skin symptoms, such as pancreatic panniculitis, acanthosis nigricans, livedo reticularis, necrolytic migratory erythema, cutaneous signs of hemorrhage, as in persons with severe acute pancreatitis, or the finding of cutaneous metastases of pancreatic carcinoma, which may be a sign of advanced disease. The pancreas is therefore one of those organs for which diagnosis and therapy are often multidisciplinary. In this review article, we summarize current knowledge of the possible skin manifestations of pancreatic disorders.
1st Department of Dermatovenerology St Anne's University Hospital Brno Czech Republic
Central European Institute of Technology Masaryk University Brno Czech Republic
Department of Dermatology Military Hospital Brno Czech Republic
Department of Gastroenterology and Internal Medicine University Hospital Brno Czech Republic
Department of Pediatrics University Hospital Brno Czech Republic
Department of Surgery University Hospital Brno Czech Republic
Faculty of Medicine and Dentistry Palacky University Olomouc Czech Republic
Zobrazit více v PubMed
Lee PJ, Papachristou GI. New insights into acute pancreatitis. Nat Rev Gastroenterol Hepatol 2019;16(8):479-96. PubMed DOI
Díte P, Starý K, Novotný I, Precechtelová M, Dolina J, Lata J, Zboril V. Incidence of chronic pancreatitis in the Czech Republic. Eur J Gastroenterol Hepatol 2001;13(6):749-50. PubMed DOI
Dušek L, Mužík J, Kubásek M, Koptíková J, Žaloudík J, Vyzula R. Epidemiology of Malignant Tumours in the Czech Republic, Version 7.0; Masaryk University: Brno, Czech Republic, 2005; ISSN 1802-8861. Available online: http://www.svod.cz
Miulescu R, Balaban DV, Sandru F, Jinga M. Cutaneous Manifestations in Pancreatic Diseases-A Review. J Clin Med 2020;9(8):2611. PubMed DOI
Requena L, Sánchez Yus E. Panniculitis. Part II. Mostly lobular panniculitis. J Am Acad Dermatol 2001;45(3):325-61. PubMed DOI
Chiari H: Über die sogenannte Fettnekrose. Prag Med Wochenschr 1883;8:255-56.
Johnson MA, Kannan DG, Balachandar TG, Jeswanth S, Rajendran S, Surendran R. Acute septal panniculitis. A cutaneous marker of a very early stage of pancreatic panniculitis indicating acute pancreatitis. JOP 2005;6(4):334-8. PubMed
Fernández-Sartorio C, Combalia A, Ferrando J, Alsina M, Iranzo P, Estrach T, Hernández-Ruiz E, Mascaró JM Jr. Pancreatic panniculitis: A case series from a tertiary university hospital in Spain. Australas J Dermatol 2018;59(4):e269-e272. PubMed DOI
Lee WS, Kim MY, Kim SW, Paik CN, Kim HO, Park YM. Fatal pancreatic panniculitis associated with acute pancreatitis: a case report. J Korean Med Sci 2007;22(5):914-7. PubMed DOI
Lyon MJ. Metabolic panniculitis: alpha-1 antitrypsin deficiency panniculitis and pancreatic panniculitis. Dermatol Ther 2010;23(4):368-74. PubMed DOI
Dan P, Rosenblat G, Yedgar S. Phospholipase A₂ activities in skin physiology and pathology. Eur J Pharmacol 2012;691(1-3):1-8. PubMed DOI
Graham PM, Altman DA, Gildenberg SR. Panniculitis, pancreatitis, and polyarthritis: a rare clinical syndrome. Cutis 2018;101(1):E34-E37. PubMed
Arbeláez-Cortés A, Vanegas-García AL, Restrepo-Escobar M, Correa-Londoño LA, González-Naranjo LA. Polyarthritis and pancreatic panniculitis associated with pancreatic carcinoma: review of the literature. J Clin Rheumatol 2014;20(8):433-6. PubMed DOI
Aznar-Oroval E, Illueca-Ballester C, Sanmartín-Jiménez O, Martínez-Lapiedra C, Santos-Corés J. Paniculitis pancreática como forma de presentación inicial de adenocarcinoma gástrico con metástasis hepáticas. Rev Esp Patol 2013;46(1):40-4. DOI
Bagazgoitia L, Alonso T, Ríos-Buceta L, Ruedas A, Carrillo R, Muñoz-Zato E. Pancreatic panniculitis: an atypical clinical presentation. Eur J Dermatol 2009;19(2):191-2. PubMed DOI
Song X, Zheng S, Yang G, Xiong G, Cao Z, Feng M, Zhang T, Zhao Y. Glucagonoma and the glucagonoma syndrome. Oncol Lett 2018;15(3):2749-755. PubMed DOI
Becker SW, Kahn D, Rotham S. Cutaneous manifestations of internal malignant tumors. Arch Derm Syphilol 1942;45(6):1069-80. DOI
Lévy-Bohbot N, Merle C, Goudet P, Delemer B, Calender A, Jolly D, Thiéfin G, Cadiot G; Groupe des Tumeurs Endocrines. Prevalence, characteristics and prognosis of MEN 1-associated glucagonomas, VIPomas, and somatostatinomas: study from the GTE (Groupe des Tumeurs Endocrines) registry. Gastroenterol Clin Biol 2004;28(11):1075-81. PubMed DOI
Tierney EP, Badger J. Etiology and pathogenesis of necrolytic migratory erythema: review of the literature. MedGenMed 2004;6(3):4.
van Beek AP, de Haas ER, van Vloten WA, Lips CJ, Roijers JF, Canninga-van Dijk MR. The glucagonoma syndrome and necrolytic migratory erythema: a clinical review. Eur J Endocrinol 2004;151(5):531-7. PubMed DOI
Schwartz RA. Acanthosis nigricans. J Am Acad Dermatol 1994;31(1):1-19. PubMed DOI
Puri N. A study of pathogenesis of acanthosis nigricans and its clinical implications. Indian J Dermatol 2011;56(6):678-83. PubMed DOI
Alkeswani A, Pierce E, Elmets CA. Idiopathic extensive acanthosis nigricans with a variant of the epidermal growth factor receptor. JAAD Case Rep 2020;6(2):79-82. PubMed DOI
Wilgenbus K, Lentner A, Kuckelkorn R, Handt S, Mittermayer C. Further evidence that acanthosis nigricans maligna is linked to enhanced secretion by the tumour of transforming growth factor alpha. Arch Dermatol Res 1992;284(5):266-70. PubMed DOI
Koyama S, Ikeda K, Sato M, Shibahara K, Yuhara K, Fukutomi H, Fukunaga K, Kanazawa N, Yuzawa K, Fukao K, Iijima T, Kikuchi M, Tomiya T, Fujiwara K. Transforming growth factor-alpha (TGF alpha)-producing gastric carcinoma with acanthosis nigricans: an endocrine effect of TGF alpha in the pathogenesis of cutaneous paraneoplastic syndrome and epithelial hyperplasia of the esophagus. J Gastroenterol 1997;32(1):71-7. PubMed DOI
Barman B, Devi LP, Thakur BK, Raphael V. Tripe Palms and Acanthosis Nigricans: A Clue for Diagnosis of Advanced Pancreatic Adenocarcinoma. Indian Dermatol Online J 2019;10(4):453-55. PubMed DOI
Lankisch PG, Weber-Dany B, Maisonneuve P, Lowenfels AB. Skin signs in acute pancreatitis: frequency and implications for prognosis. J Intern Med 2009;265(2):299-301. PubMed DOI
Pandiaraja J. Another cutaneous sign of acute pancreatitis. Indian J Crit Care Med 2016;20(5):313-4. PubMed DOI
Dickson AP, Imrie CW. The incidence and prognosis of body wall ecchymosis in acute pancreatitis. Surg Gynecol Obstet 1984;159(4):343-7.
Fujiwara T, Takehara Y, Ichijo K, Tooyama N, Kodaira N, Yamamoto H, Watahiki H. Anterior extension of acute pancreatitis: CT findings. J Comput Assist Tomogr 1995;19(6):963-6. PubMed DOI
Rahbour G, Ullah MR, Yassin N, Thomas GP. Cullen's sign - Case report with a review of the literature. Int J Surg Case Rep 2012;3(5):143-6. PubMed DOI
Sajjan VV, Lunge S, Swamy MB, Pandit AM. Livedo reticularis: A review of the literature. Indian Dermatol Online J 2015;6(5):315-21. PubMed DOI
Ehrmann S. Ein neues Gefaβsymptom bei Lues. Wien Med Wochenschr 1907;57:777-82.
Uthman IW, Khamashta MA. Livedo racemosa: a striking dermatological sign for the antiphospholipid syndrome. J Rheumatol 2006;33(12):2379-82. PubMed
Walzel P. Ueber das Symptom der flecken- und gitterförmigen Zyanose bei akuter Pankreasnekrose. Wien Klin Wochenschr 1927;40:218-9.
Gould JW, Helms SE, Schulz SM, Stevens SR. Relapsing livedo reticularis in the setting of chronic pancreatitis. J Am Acad Dermatol 1998;39(6):1035-6. PubMed DOI
Takemura N, Fujii N, Tanaka T. Cutaneous metastasis as the first clinical manifestation of pancreatic adenocarcinoma: a case treated with gemcitabine. J Dermatol 2007;34(9):662-4. PubMed DOI
Gawrieh S, Massey BT, Komorowski RA. Scalp metastases as the first manifestation of pancreatic cancer. Dig Dis Sci 2002;47(7):1469-71. PubMed DOI
Miyahara M, Hamanaka Y, Kawabata A, Sato Y, Tanaka A, Yamamoto A, Ueno T, Nishihara K, Suzuki T. Cutaneous metastases from pancreatic cancer. Int J Pancreatol 1996;20(2):127-30. PubMed DOI
Shin WY, Lee KY, Ahn SI, Park SY, Park KM. Cutaneous metastasis as an initial presentation of a non-functioning pancreatic neuroendocrine tumor. World J Gastroenterol 2015;21(33):9822-6. PubMed DOI
Jedrych J, Busam K, Klimstra DS, Pulitzer M. Cutaneous metastases as an initial manifestation of visceral well-differentiated neuroendocrine tumor: a report of four cases and a review of literature. J Cutan Pathol 2014;41(2):113-22. PubMed DOI
Zhou HY, Wang XB, Gao F, Bu B, Zhang S, Wang Z. Cutaneous metastasis from pancreatic cancer: A case report and systematic review of the literature. Oncol Lett 2014;8(6):2654-60. PubMed DOI