Non-Occlusive Mesenteric Ischemia in Cardiac Arrest Patients

. 2023 Sep ; 24 (9) : 262. [epub] 20230919

Status PubMed-not-MEDLINE Jazyk angličtina Země Singapur Médium electronic-ecollection

Typ dokumentu časopisecké články, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/pmid39076401
Odkazy

PubMed 39076401
PubMed Central PMC11270105
DOI 10.31083/j.rcm2409262
PII: S1530-6550(23)01025-6
Knihovny.cz E-zdroje

Non-occlusive mesenteric ischemia (NOMI) is a severe complication in patients after cardiac arrest (CA). The diagnosis is complicated, the treatment options are limited. Given the susceptibility of enterocytes to ischemia, the incidence and severity of NOMI in the post-resuscitation period may reflect the intensity and duration of both ischemia and subsequent reperfusion injury. NOMI is considered to be associated with adverse neurological outcomes in CA patients. Therefore, NOMI should not only be regarded as a post-resuscitation complication but also as one of the prognostic markers in CA patients.This paper summarizes current knowledge on NOMI's pathophysiology, diagnosis, treatment, and prognostic significance in CA patients.

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Clair DG, Beach JM. Mesenteric Ischemia. The New England Journal of Medicine . 2016;374:959–968. PubMed

Trompeter M, Brazda T, Remy CT, Vestring T, Reimer P. Non-occlusive mesenteric ischemia: etiology, diagnosis, and interventional therapy. European Radiology . 2002;12:1179–1187. PubMed

Stahl K, Busch M, Maschke SK, Schneider A, Manns MP, Fuge J, et al. A Retrospective Analysis of Nonocclusive Mesenteric Ischemia in Medical and Surgical ICU Patients: Clinical Data on Demography, Clinical Signs, and Survival. Journal of Intensive Care Medicine . 2020;35:1162–1172. PubMed PMC

Renaudier M, de Roux Q, Bougouin W, Boccara J, Dubost B, Attias A, et al. Acute mesenteric ischaemia in refractory shock on veno-arterial extracorporeal membrane oxygenation. European Heart Journal. Acute Cardiovascular Care . 2020;10:62–70. PubMed

Paul M, Bougouin W, Legriel S, Charpentier J, Jaubert P, Savary G, et al. Frequency, risk factors, and outcomes of non-occlusive mesenteric ischaemia after cardiac arrest. Resuscitation . 2020;157:211–218. PubMed

Schoots IG, Koffeman GI, Legemate DA, Levi M, van Gulik TM. Systematic review of survival after acute mesenteric ischaemia according to disease aetiology. The British Journal of Surgery . 2004;91:17–27. PubMed

Bassiouny HS. Nonocclusive mesenteric ischemia. The Surgical Clinics of North America . 1997;77:319–326. PubMed

Soussi S, Taccori M, De Tymowski C, Depret F, Chaussard M, Fratani A, et al. Risk Factors for Acute Mesenteric Ischemia in Critically Ill Burns Patients-A Matched Case-Control Study. Shock . 2019;51:153–160. PubMed

Wurm R, Cho A, Arfsten H, van Tulder R, Wallmüller C, Steininger P, et al. Non-occlusive mesenteric ischaemia in out of hospital cardiac arrest survivors. European Heart Journal: Acute Cardiovascular Care . 2018;7:450–458. PubMed

Wilcox MG, Howard TJ, Plaskon LA, Unthank JL, Madura JA. Current theories of pathogenesis and treatment of nonocclusive mesenteric ischemia. Digestive Diseases and Sciences . 1995;40:709–716. PubMed

Samel S, Keese M, Kleczka M, Lanig S, Gretz N, Hafner M, et al. Microscopy of bacterial translocation during small bowel obstruction and ischemia in vivo–a new animal model. BMC Surgery . 2002;2:6. PubMed PMC

Aschoff AJ, Stuber G, Becker BW, Hoffmann MHK, Schmitz BL, Schelzig H, et al. Evaluation of acute mesenteric ischemia: accuracy of biphasic mesenteric multi-detector CT angiography. Abdominal Imaging . 2009;34:345–357. PubMed

Bala M, Kashuk J, Moore EE, Kluger Y, Biffl W, Gomes CA, et al. Acute mesenteric ischemia: guidelines of the World Society of Emergency Surgery. World Journal of Emergency Surgery . 2017;12:38. PubMed PMC

Lundgren O, Haglund U. The pathophysiology of the intestinal countercurrent exchanger. Life Sciences . 1978;23:1411–1422. PubMed

Thuijls G, van Wijck K, Grootjans J, Derikx JPM, van Bijnen AA, Heineman E, et al. Early diagnosis of intestinal ischemia using urinary and plasma fatty acid binding proteins. Annals of Surgery . 2011;253:303–308. PubMed

Adrie C, Adib-Conquy M, Laurent I, Monchi M, Vinsonneau C, Fitting C, et al. Successful cardiopulmonary resuscitation after cardiac arrest as a “sepsis-like” syndrome. Circulation . 2002;106:562–568. PubMed

Jozwiak M, Bougouin W, Geri G, Grimaldi D, Cariou A. Post-resuscitation shock: recent advances in pathophysiology and treatment. Annals of Intensive Care . 2020;10:170. PubMed PMC

Piton G, Belin N, Barrot L, Belon F, Cypriani B, Navellou JC, et al. Enterocyte Damage: A Piece in the Puzzle of Post-Cardiac Arrest Syndrome. Shock . 2015;44:438–444. PubMed

Hulten L, Jodal M, Lindhagen J, Lundgren O. Blood flow in the small intestine of cat and man as analyzed by an inert gas washout technique. Gastroenterology . 1976;70:45–51. PubMed

Matheson PJ, Wilson MA, Garrison RN. Regulation of intestinal blood flow. The Journal of Surgical Research . 2000;93:182–196. PubMed

Lubner M, Demertzis J, Lee JY, Appleton CM, Bhalla S, Menias CO. CT evaluation of shock viscera: a pictorial review. Emergency Radiology . 2008;15:1–11. PubMed

Juif A, Calame P, Winiszewski H, Turco C, Verdot P, Pili-Floury S, et al. Atherosclerosis is associated with poorer outcome in non-occlusive mesenteric ischemia. European Journal of Radiology . 2021;134:109453. PubMed

Yandza T, Tauc M, Saint-Paul MC, Ouaissi M, Gugenheim J, Hébuterne X. The pig as a preclinical model for intestinal ischemia-reperfusion and transplantation studies. The Journal of Surgical Research . 2012;178:807–819. PubMed

Reilly PM, Wilkins KB, Fuh KC, Haglund U, Bulkley GB. The mesenteric hemodynamic response to circulatory shock: an overview. Shock . 2001;15:329–343. PubMed

Kolkman JJ, Groeneveld AB. Occlusive and non-occlusive gastrointestinal ischaemia: a clinical review with special emphasis on the diagnostic value of tonometry. Scandinavian Journal of Gastroenterology . 1998;225:3–12. PubMed

O’Dwyer C, Woodson LC, Conroy BP, Lin CY, Deyo DJ, Uchida T, et al. Regional perfusion abnormalities with phenylephrine during normothermic bypass. The Annals of Thoracic Surgery . 1997;63:728–735. PubMed

Tofukuji M, Stahl GL, Metais C, Tomita M, Agah A, Bianchi C, et al. Mesenteric dysfunction after cardiopulmonary bypass: role of complement C5a. The Annals of Thoracic Surgery . 2000;69:799–807. PubMed

Boley SJ, Brandt LJ, Sammartano RJ. History of mesenteric ischemia. The evolution of a diagnosis and management. The Surgical Clinics of North America . 1997;77:275–288. PubMed

Schölmerich J, Herfarth C. Gefäßerkrankungen des Dünndarms und des Kolons. In: Siewert JR, Harder F, Rothmund M, editors. Praxis der Viszeralchirurgie . Springer; Berlin Heidelberg: 2002. pp. 453–468.

Mirvis SE, Shanmuganathan K, Erb R. Diffuse small-bowel ischemia in hypotensive adults after blunt trauma (shock bowel): CT findings and clinical significance. American Journal of Roentgenology . 1994;163:1375–1379. PubMed

Hinnebusch BF, Ma Q, Henderson JW, Siddique A, Archer SY, Hodin RA. Enterocyte response to ischemia is dependent on differentiation state. Journal of Gastrointestinal Surgery . 2002;6:403–409. PubMed

Kanda T, Nakatomi Y, Ishikawa H, Hitomi M, Matsubara Y, Ono T, et al. Intestinal fatty acid-binding protein as a sensitive marker of intestinal ischemia. Digestive Diseases and Sciences . 1992;37:1362–1367. PubMed

Bradbury AW, Brittenden J, McBride K, Ruckley CV. Mesenteric ischaemia: a multidisciplinary approach. The British Journal of Surgery . 1995;82:1446–1459. PubMed

Kompan L, Kremzar B, Gadzijev E, Prosek M. Effects of early enteral nutrition on intestinal permeability and the development of multiple organ failure after multiple injury. Intensive Care Medicine . 1999;25:157–161. PubMed

Faries PL, Simon RJ, Martella AT, Lee MJ, Machiedo GW. Intestinal permeability correlates with severity of injury in trauma patients. The Journal of Trauma . 1998;44:1031–1036. PubMed

Fink MP, Delude RL. Epithelial barrier dysfunction: a unifying theme to explain the pathogenesis of multiple organ dysfunction at the cellular level. Critical Care Clinics . 2005;21:177–196. PubMed

Gaussorgues P, Gueugniaud PY, Vedrinne JM, Salord F, Mercatello A, Robert D. Bacteremia following cardiac arrest and cardiopulmonary resuscitation. Intensive Care Medicine . 1988;14:575–577. PubMed

Piton G, Le Gouge A, Boisramé-Helms J, Anguel N, Argaud L, Asfar P, et al. Factors associated with acute mesenteric ischemia among critically ill ventilated patients with shock: a post hoc analysis of the NUTRIREA2 trial. Intensive Care Medicine . 2022;48:458–466. PubMed

Gutierrez A, Carlson C, Kalra R, Elliott AM, Yannopoulos D, Bartos JA. Outcomes associated with delayed enteral feeding after cardiac arrest treated with veno-arterial extracorporeal membrane oxygenation and targeted temperature management. Resuscitation . 2021;164:20–26. PubMed

Konan A, Piton G, Ronot M, Hassoun Y, Winiszewski H, Besch G, et al. Abdominal atherosclerosis is not a risk factor of nonocclusive mesenteric ischemia among critically ill patients: a propensity matching study. Annals of Intensive Care . 2022;12:117. PubMed PMC

Kolkman JJ, Mensink PBF. Non-occlusive mesenteric ischaemia: a common disorder in gastroenterology and intensive care. Best Practice & Research. Clinical Gastroenterology . 2003;17:457–473. PubMed

Versyck G, de Gheldere C, Vanclooster P. Non-occlusive mesenteric ischemia: two case reports and a short review of the literature. Acta Chirurgica Belgica . 2018;118:392–397. PubMed

Schriefl C, Steininger P, Clodi C, Mueller M, Poppe M, Ettl F, et al. The association of early diarrhea after successful resuscitation following out-of-hospital cardiac arrest with neurological outcome: A retrospective observational study. Medicine . 2021;100:e28164. PubMed PMC

Belohlavek J, Smalcova J, Rob D, Franek O, Smid O, Pokorna M, et al. Effect of Intra-arrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Immediate Invasive Assessment and Treatment on Functional Neurologic Outcome in Refractory Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial. Journal of the American Medical Association . 2022;327:737–747. PubMed PMC

Pérez-García C, de Miguel Campos E, Fernández Gonzalo A, Malfaz C, Martín Pinacho JJ, Fernández Álvarez C, et al. Non-occlusive mesenteric ischaemia: CT findings, clinical outcomes and assessment of the diameter of the superior mesenteric artery. The British Journal of Radiology . 2018;91:20170492. PubMed PMC

Furukawa A, Kanasaki S, Kono N, Wakamiya M, Tanaka T, Takahashi M, et al. CT diagnosis of acute mesenteric ischemia from various causes. American Journal of Roentgenology . 2009;192:408–416. PubMed

Evennett NJ, Petrov MS, Mittal A, Windsor JA. Systematic review and pooled estimates for the diagnostic accuracy of serological markers for intestinal ischemia. World Journal of Surgery . 2009;33:1374–1383. PubMed

Philpotts LE, Heiken JP, Westcott MA, Gore RM. Colitis: use of CT findings in differential diagnosis. Radiology . 1994;190:445–449. PubMed

Tujjar O, Mineo G, Dell’Anna A, Poyatos-Robles B, Donadello K, Scolletta S, et al. Acute kidney injury after cardiac arrest. Critical Care . 2015;19:169. PubMed PMC

Rundgren M, Ullén S, Morgan MPG, Glover G, Cranshaw J, Al-Subaie N, et al. Renal function after out-of-hospital cardiac arrest; the influence of temperature management and coronary angiography, a post hoc study of the target temperature management trial. Critical Care . 2019;23:163. PubMed PMC

Chen N, Callaway CW, Guyette FX, Rittenberger JC, Doshi AA, Dezfulian C, et al. Arrest etiology among patients resuscitated from cardiac arrest. Resuscitation . 2018;130:33–40. PubMed PMC

Bourcier S, Klug J, Nguyen LS. Non-occlusive mesenteric ischemia: Diagnostic challenges and perspectives in the era of artificial intelligence. World Journal of Gastroenterology . 2021;27:4088–4103. PubMed PMC

Memet O, Zhang L, Shen J. Serological biomarkers for acute mesenteric ischemia. Annals of Translational Medicine . 2019;7:394. PubMed PMC

Tilsed JVT, Casamassima A, Kurihara H, Mariani D, Martinez I, Pereira J, et al. ESTES guidelines: acute mesenteric ischaemia. European Journal of Trauma and Emergency Surgery . 2016;42:253–270. PubMed PMC

Hoftun Farbu B, Langeland H, Ueland T, Michelsen AE, Jørstad Krüger A, Klepstad P, et al. Intestinal injury in cardiac arrest is associated with multiple organ dysfunction: A prospective cohort study. Resuscitation . 2023;185:109748. PubMed

Shi H, Wu B, Wan J, Liu W, Su B. The role of serum intestinal fatty acid binding protein levels and D-lactate levels in the diagnosis of acute intestinal ischemia. Clinics and Research in Hepatology and Gastroenterology . 2015;39:373–378. PubMed

Schellekens DHSM, Reisinger KW, Lenaerts K, Hadfoune M, Olde Damink SW, Buurman WA, et al. SM22 a Plasma Biomarker for Human Transmural Intestinal Ischemia. Annals of Surgery . 2018;268:120–126. PubMed

Krychtiuk KA, Richter B, Lenz M, Hohensinner PJ, Huber K, Hengstenberg C, et al. Epinephrine treatment but not time to ROSC is associated with intestinal injury in patients with cardiac arrest. Resuscitation . 2020;155:32–38. PubMed

Grimaldi D, Guivarch E, Neveux N, Fichet J, Pène F, Marx JS, et al. Markers of intestinal injury are associated with endotoxemia in successfully resuscitated patients. Resuscitation . 2013;84:60–65. PubMed

Guo Q, Kawahata I, Degawa T, Ikeda-Matsuo Y, Sun M, Han F, et al. Fatty Acid-Binding Proteins Aggravate Cerebral Ischemia-Reperfusion Injury in Mice. Biomedicines . 2021;9:529. PubMed PMC

Hansen C, Sastre C, Wolcott Z, Bevers MB, Kimberly WT. Time-dependent, dynamic prediction of fatty acid-binding protein 4, Galectin-3, and soluble ST2 measurement with poor outcome after acute stroke. International Journal of Stroke . 2021;16:660–668. PubMed PMC

Pelsers MM, Hanhoff T, Van der Voort D, Arts B, Peters M, Ponds R, et al. Brain- and heart-type fatty acid-binding proteins in the brain: tissue distribution and clinical utility. Clinical Chemistry . 2004;50:1568–1575. PubMed

Crenn P, Messing B, Cynober L. Citrulline as a biomarker of intestinal failure due to enterocyte mass reduction. Clinical Nutrition . 2008;27:328–339. PubMed

Crenn P, Coudray-Lucas C, Thuillier F, Cynober L, Messing B. Postabsorptive plasma citrulline concentration is a marker of absorptive enterocyte mass and intestinal failure in humans. Gastroenterology . 2000;119:1496–1505. PubMed

van Haren FMP, Sleigh JW, Pickkers P, Van der Hoeven JG. Gastrointestinal perfusion in septic shock. Anaesthesia and Intensive Care . 2007;35:679–694. PubMed

Demir IE, Ceyhan GO, Friess H. Beyond lactate: is there a role for serum lactate measurement in diagnosing acute mesenteric ischemia. Digestive Surgery . 2012;29:226–235. PubMed

Poeze M, Froon AH, Greve JW, Ramsay G. D-lactate as an early marker of intestinal ischaemia after ruptured abdominal aortic aneurysm repair. The British Journal of Surgery . 1998;85:1221–1224. PubMed

Liu D, Cao S, Zhou Y, Xiong Y. Recent advances in endotoxin tolerance. Journal of Cellular Biochemistry . 2019;120:56–70. PubMed

Grimaldi D, Legriel S, Pichon N, Colardelle P, Leblanc S, Canouï-Poitrine F, et al. Ischemic injury of the upper gastrointestinal tract after out-of-hospital cardiac arrest: a prospective, multicenter study. Critical Care . 2022;26:59. PubMed PMC

Winzer R, Fedders D, Backes M, Ittermann T, Gründling M, Mensel B, et al. Local Intra-arterial Vasodilator Infusion in Non-Occlusive Mesenteric Ischemia Significantly Increases Survival Rate. CardioVascular and Interventional Radiology . 2020;43:1148–1155. PubMed PMC

Rittgerodt N, Pape T, Busch M, Becker LS, Schneider A, Wedemeyer H, et al. Predictors of response to intra-arterial vasodilatory therapy of non-occlusive mesenteric ischemia in patients with severe shock: results from a prospective observational study. Critical Care . 2022;26:92. PubMed PMC

Grimaldi D, Sauneuf B, Guivarch E, Ricome S, Geri G, Charpentier J, et al. High Level of Endotoxemia Following Out-of-Hospital Cardiac Arrest Is Associated With Severity and Duration of Postcardiac Arrest Shock. Critical Care Medicine . 2015;43:2597–2604. PubMed

Piton G, Capellier G. Biomarkers of gut barrier failure in the ICU. Current Opinion in Critical Care . 2016;22:152–160. PubMed

Suzuki S, Kondo H, Furukawa A, Kawai K, Yukaya T, Shimazui T, et al. Prognostic Factors of Preoperative Examinations for Non-occlusive Mesenteric Ischemia: A Multicenter Retrospective Project Study Conducted by the Japanese Society for Abdominal Emergency Medicine. World Journal of Surgery . 2020;44:3687–3694. PubMed

Toda Y, Komatsu S, Fukami Y, Saito T, Matsumura T, Osawa T, et al. Prognostic factors for the successful conservative management of nonocclusive mesenteric ischemia. World Journal of Emergency Surgery . 2022;17:32. PubMed PMC

Meilahn JE, Morris JB, Ceppa EP, Bulkley GB. Effect of prolonged selective intramesenteric arterial vasodilator therapy on intestinal viability after acute segmental mesenteric vascular occlusion. Annals of Surgery . 2001;234:107–115. PubMed PMC

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