An Infective Endocarditis Case Report Involving Both Native Aortic and Mitral Valves Due to Streptococcus Vestibularis
Language English Country Czech Republic Media print
Document type Case Reports, Journal Article
PubMed
40026160
DOI
10.14712/23362936.2025.4
PII: pmr_2025126010026
Knihovny.cz E-resources
- Keywords
- Bicuspid aortic valves, Infective endocarditis, Periannular abscesses, Streptococcus vestibularis,
- MeSH
- Anti-Bacterial Agents therapeutic use MeSH
- Aortic Valve Insufficiency * microbiology surgery MeSH
- Endocarditis, Bacterial * complications diagnosis drug therapy microbiology MeSH
- Bicuspid Aortic Valve Disease * complications surgery MeSH
- Third Generation Cephalosporins therapeutic use MeSH
- Ceftriaxone therapeutic use MeSH
- Heart Valve Prosthesis Implantation MeSH
- Adult MeSH
- Humans MeSH
- Mitral Valve * microbiology MeSH
- Penicillin G therapeutic use MeSH
- Penicillin Resistance MeSH
- Streptococcal Infections * complications diagnosis drug therapy microbiology MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Male MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- Third Generation Cephalosporins MeSH
- Ceftriaxone MeSH
- Penicillin G MeSH
Infective endocarditis (IE) is a life-threatening disease, with its mortality rate varying depending on the infectious agent. Streptococci are among the most common causes of infective endocarditis. However, Streptococcus vestibularis has rarely been associated with human infections, typically affecting patients with underlying conditions such as immunosuppressive diseases, valve replacement, rheumatic heart disease, and hemodialysis. We present the case of a 26-year-old man who presented with fever, unanticipated weight loss, and fatigue. Although no typical risk factors for infective endocarditis were identified at admission, transesophageal echocardiography revealed a bicuspid aortic valve with calcification, paravalvular aortic abscess formation, and vegetations on the anterior leaflet of the mitral valve. Blood cultures grew S. vestibularis, which was initially sensitive to benzylpenicillin but developed emergent resistance on the third day of the antibiotic treatment. Subsequently, ceftriaxone therapy was initiated, and blood cultures became sterile on day 10. The patient eventually underwent aortic valve replacement. We report the first known case of native aortic and mitral valve endocarditis caused by S. vestibularis, accompanied by a paravalvular abscess around the native aortic valve, in a patient who had no typical risk factors for infective endocarditis, except for a bicuspid aortic valve.
Department of Cardiology Dokuz Eylul Universitesi Hastanesi Izmir Turkey
Department of Cardiovascular Surgery Dokuz Eylul Universitesi Hastanesi Izmir Turkey
Department of Internal Medicine Dokuz Eylul Universitesi Hastanesi Izmir Turkey
Faculty of Medicine Dokuz Eylul Universitesi Hastanesi Izmir Turkey
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