Study of directional pulsed neutron flux generation for BNCT using a high-intensity lithium beam
Status PubMed-not-MEDLINE Jazyk angličtina Země Velká Británie, Anglie Médium print-electronic
Typ dokumentu časopisecké články
PubMed
40344953
DOI
10.1016/j.apradiso.2025.111872
PII: S0969-8043(25)00217-9
Knihovny.cz E-zdroje
- Publikační typ
- časopisecké články MeSH
This paper introduces a novel neutron production system for Boron Neutron Capture Therapy (BNCT) that employs a lithium beam in inverse kinematics to generate forward-directed neutrons through the 7Li (p,n)7Be reaction. The system utilizes a thin polypropylene target and an optimized beam configuration to achieve high neutron yield and precise directional control. A tape target mechanism is incorporated to effectively manage thermal loads, ensuring stable and reliable operation. The proposed system could offer substantial advantages over conventional neutron sources, including enhanced neutron directionality and a reduced shielding requirement. This approach increases the potential for precise tumor targeting while minimizing exposure to surrounding healthy tissues, paving the way for a more accessible and efficient BNCT treatment option.
Brookhaven National Laboratory NY USA
Brookhaven National Laboratory NY USA; Institute of Science Tokyo Tokyo Japan
Nagaoka University of Technology Niigata Japan
Nuclear Physics Institute of the Czech Academy of Science Husinec Rez Czech Republic
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