Initiatives to increase childhood vaccination coverage: an international comparison

. 2025 Aug ; 158 () : 105351. [epub] 20250519

Jazyk angličtina Země Irsko Médium print-electronic

Typ dokumentu časopisecké články, srovnávací studie, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/pmid40449380

Background Childhood vaccination rates fluctuate over time and do not always meet the levels recommended by the WHO. Objective This study aims to provide an overview of measures countries have introduced to increase vaccination rates. Methods We developed a structured data collection template that was completed by country experts from Europe, Israel, the USA, and Canada. Experts were identified using the European Observatory on Health Systems and Policies' HSPM (Health Systems and Policy Monitor) network. We approached experts from 32 countries and received responses from 22 countries. In the template we asked for measures introduced between 2014 and 2019. The experts were asked to indicate the type of intervention, the target population, possible positive and negative effects, and evidence on effectiveness. The information was collected between September 2019 and January 2020. Results We identified four main types of interventions: restrictive measures for the unvaccinated, financial incentives, measures supporting the logistics of vaccination, and vaccination promotion campaigns. Restrictive measures often involved expanding existing mandatory vaccination policies or limiting access to pre-school activities for unvaccinated children. Financial incentives for healthcare providers showed some positive effects. Regarding logistical support, several countries used schools as alternative vaccination sites, though this presented organisational challenges. Many countries invested in improving knowledge among both healthcare professionals and parents to encourage vaccine uptake. Conclusions Most initiatives implemented in the countries covered focussed on communication and knowledge enhancement. However, there is limited evidence on the impact of these measures on vaccination coverage.

Andrija Stampar School of Public Health University of Zagreb School of Medicine 4 Rockefeller Street Zagreb 10 000 Republic of Croatia

Austrian National Public Health Institute Stubenring 6 1010 Vienna Austria

Center for Social and Economic Strategies Faculty of Social Sciences Charles University Smetanovo nábřeží 6 110 01 Prague 1 Czechia

Dalla Lana School of Public Health University of Toronto Canada

Departement Gesundheitswissenschaften und Medizin Universität Luzern

Department of Health Care Management WHO Collaborating Centre for Health Systems Research and Management Berlin University of Technology Straße des 17 Juni 135 H 80 10623 Berlin Germany

Department of Life Sciences and Public Health Università Cattolica del Sacro Cuore and Fondazione Policlinico Universitario A Gemelli IRCCS Largo Agostino Gemelli 8 00168 Roma Italy

Department of Public Health Health Sciences Institute Faculty of Medicine Vilnius university M K Čiurlionio 21 27 LT 03101 Vilnius Lithuania

Escola Nacional de Saúde Pública Lisboa Portugal

European Observatory on Health Systems and Policies London School of Hygiene and Tropical Medicine London WC1E 7HT UK

European University Nicosia Cyprus

Faculty of Public Health Medical University Varna 55 Marin Drinov Str Varna Bulgaria

Institute of Health Policy Management and Evaluation University of Toronto Canada

Jagiellonian University Medical College Faculty of Health Sciences Institute of Public Health Krakow Poland

Lund University School of Economics and Management P O Box 7080 220 07 Lund Sweden

McMaster University Hamilton Canada

Myers JDC Brookdale Institute Jerusalem Israel; and Department of Health Care Management Technische Universität Berlin Berlin Germany

Nivel Otterstraat 118 124 3513 CR Utrecht Netherlands

Nivel Utrecht Netherlands and Maastricht University

Norwegian Institute of Public Health PO Box 222 Skøyen N 0213 Oslo Norway

Open University of Cyprus Nicosia Cyprus

Panteion University of Social and Political Sciences Athens Greece

Semmelweis University 1125 Budapest Kútvölgyi út 2 Hungary

The Faculty of Health and Sports Sciences Riga Stradins Univesrity Latvia 16 Dzirciema str LV 1007 Latvia

World Health Organization Regional Office for Europe formerly from WHO Country Office in Estonia

Zobrazit více v PubMed

OECD, Health at a glance 2019: OECD indicators. 2019: Paris.

OECD, OECD Health database. 2023, OECD.

WHO. Human papillomavirus (HPV) and cervical cancer. 2020 11-11-2020 [cited 2021 02-11-2021]; Available from: https://www.who.int/en/news-room/fact-sheets/detail/human-papillomavirus-(hpv)-and-cervical-cancer.

WHO Regional Office for Europe. Human papillomavirus (HPV). 2021 [cited 2021 02-11-2021]; Available from: https://www.euro.who.int/en/health-topics/disease-prevention/vaccines-and-immunization/vaccine-preventable-diseases/human-papillomavirus-hpv2.

Bruni, L. and B. Serrano, Putting HPV on the map: the state of HPV prevention in the WHO European Region. 2022: Brussels.

Desai A.N., Majumder M.S.J. What is herd immunity? JAMA. 2020;324(20):2113. PubMed

Attwell K., Navin M.C. Childhood vaccination mandates: scope, sanctions, severity, selectivity, and salience. Milbank Quarterly, 2019;97(4):978–1014. PubMed PMC

Essoh T.A., et al. Vol. 23. BMC Public Health; 2023. p. 912. (Exploring the factors contributing to low vaccination uptake for nationally recommended routine childhood and adolescent vaccines in kenya). PubMed PMC

Navin M.C., et al. Vaccine education, reasons for refusal, and vaccination behavior. Am J Prev Med. 2019;56(3):359–367. PubMed

Kumar D., et al. Understanding the phases of vaccine hesitancy during the COVID-19 pandemic. Isr J Health Policy Res. 2022;11(1):16. PubMed PMC

Thomson A., Robinson K., Vallee-Tourangeau G. The 5As: a practical taxonomy for the determinants of vaccine uptake. Vaccine. 2016;34(8):1018–1024. PubMed

Betsch C., et al. Beyond confidence: development of a measure assessing the 5C psychological antecedents of vaccination. PLoS One. 2018;13(12) PubMed PMC

Benoit S.L., Mauldin R.F. The "anti-vax" movement: a quantitative report on vaccine beliefs and knowledge across social media. BMC Public Health. 2021;21(1):2106. PubMed PMC

World Health Organization, r.o.f.E., TIP tailoring immunization programmes. 2019: Copenhagen.

De Jong J., et al. Utrecht; Nivel: 2019. Een verkenning [measures to increase vaccination uptake in the netherlands. an exploration. Maatregelen om de vaccinatiegraad in Nederland te verhogen.

Van Unen D. NRC handelsblad. 2019. Duitsland stelt vaccinatie tegen mazelen verplicht.

Merilind E., et al. The influence of performance-based payment on childhood immunisation coverage. Health Policy. 2015;119(6):770–777. PubMed

Sabin Vaccine Institute, Legislative landscape review: legislative approaches to immunization across the European region. 2018.

Stein-Zamir C., Israeli A. Timeliness and completeness of routine childhood vaccinations in young children residing in a district with recurrent vaccine-preventable disease outbreaks. Euro Surveill. 2019;(6):24. PubMed PMC

Attwell K., et al. Recent vaccine mandates in the United States, Europe and Australia: a comparative study. Vaccine. 2018:7377–7384. PubMed

Cawkwell P.B., Oshinsky D. Childhood vaccination requirements: lessons from history, Mississippi, and a path forward. Vaccine. 2015;33(43):5884–5887. PubMed

Colgrove J., Lowin A. A tale of two states: mississippi, West Virginia, and exemptions to compulsory school vaccination laws. Health Aff. 2016:348–355. PubMed

Buttenheim A.M., et al. Conditional admission, religious exemption type, and nonmedical vaccine exemptions in California before and after a state policy change. Vaccine. 2018;36(26):3789–3793. PubMed PMC

Hall K.J., et al. Enforcement associated with higher school-reported immunization rates. Am J Prev Med. 2017;53(6):892–897. PubMed

Cattarin M., et al. Suspension of mandatory vaccination and public health preserving: rovigo local health unit experience after appliance of Veneto regional law 7/2007. J Prev Med Hyg. 2013;54(3):181–186. PubMed PMC

D'Ancona F., et al. The law on compulsory vaccination in Italy: an update 2 years after the introduction. Euro Surveill. 2019;(26):24. PubMed PMC

Expert panel on effective ways of investing in health (EXPH), vaccination programmes and health systems in the European Union. 2018.

Bassani D.G., et al. Vol. 13. BMC Public Health; 2013. p. S30. (Financial incentives and coverage of child health interventions: a systematic review and meta-analysis). PubMed PMC

Adams J., et al. Acceptability of parental financial incentives and quasi-mandatory interventions for preschool vaccinations: triangulation of findings from three linked studies. PLoS One. 2016;11(6) PubMed PMC

Desiante F., et al. Universal proposal strategies of anti-HPV vaccination for adolescents: comparative analysis between school-based and clinic immunization programs. J Prev Med Hyg. 2017:E225–E230. p. PubMed PMC

Eldred S.V., et al. A medical student-driven "vaccine blitz" at a school-based health center as an effective way to improve adolescent vaccination rates. Fam Med. 2015;47(7):546–548. PubMed

Whelan N.W., et al. Engaging parents and schools improves uptake of the human papillomavirus (HPV) vaccine: examining the role of the public health nurse. Vaccine. 2014;32(36):4665–4671. PubMed

Lim W.T., et al. Evidence of effective delivery of the human papillomavirus (HPV) vaccine through a publicly funded, school-based program: the Ontario Grade 8 HPV Vaccine Cohort Study. BMC Public Health. 2014;14:1029. PubMed PMC

Suppli C.H., et al. Written reminders increase vaccine coverage in Danish children - evaluation of a nationwide intervention using The Danish Vaccination Register, 2014 to 2015. Eurosurveillance. 2017;(17):22. PubMed PMC

Bratic J.S., Seyferth E.R., Bocchini J.A. Update on barriers to human papillomavirus vaccination and effective strategies to promote vaccine acceptance. Curr Opin Pediatr. 2016;28(3):407–412. PubMed

Holloway G.L. Effective HPV vaccination strategies: what does the evidence say? An integrated literature review. J Pediatr Nurs. 2019;44:31–41. PubMed

Crocker-Buque T., Edelstein M., Mounier-Jack S. A process evaluation of how the routine vaccination programme is implemented at GP practices in England. Implementat Sci. 2018;13(1):132. PubMed PMC

Williams D.L., et al. Louisiana physicians are increasing HPV vaccination rates. J Louisiana State Med Society. 2017;169(3):63–67. PubMed PMC

de Koning R., et al. Strategies used to improve vaccine uptake among healthcare providers: a systematic review. Vaccine X. 2024;19 PubMed PMC

Fairbrother G., et al. The impact of physician bonuses, enhanced fees, and feedback on childhood immunization coverage rates. Am J Public Health. 1999;89(2):5. PubMed PMC

Fiks A.G. P. Center for Clinical Effectiveness, and T.C.s.H.o.P. the Center for Biomedical Informatics, improving HPV vaccination rates. LDI Issue Brief. 2014;19(1):1–4. PubMed

Holford D., et al. The empathetic refutational interview to tackle vaccine misconceptions: four randomized experiments. Health Psychol. 2024 PubMed

Dubey, V., Implementing mandatory education for parents seeking a philosophical exemption: toronto Public Health’s experience. 2020, Toronto Public Health: Toronto.

Gaál P., et al. Adattudományi innováció az egészségügy környezeti kihívásainak kezelésében: a nagy adatállományok hasznosításának jelentősége és lehetőségei a járványkezelésben [Innovation in Data Science to Address the Environmental Challenges of Health Systems: the Significance and Opportunities of the Analysis of Big Routine Datasets in Pandemic Management] Scientia et Securitas. 2021;2(1):2–11.

Europeans’ attitudes towards vaccination; Report; Special Eurobarometer 488. 2019, European Commission.

Norwegian Institute of Public Health. High coverage for the Childhood Immunisation Programme in Norway. 2020 [cited 2021 10-07-2021]; Available from: https://www.fhi.no/en/news/2020/high-coverage-for-the-childhood-immunisation-programme-in-norway/.

Fadda M., et al. Effectiveness of a smartphone app to increase parents' knowledge and empowerment in the MMR vaccination decision: a randomized controlled trial. Hum Vaccin Immunother. 2017;13(11):2512–2521. PubMed PMC

Cipriano J.J., Scoloveno R., Kelly A. Increasing parental knowledge related to the Human papillomavirus (HPV) vaccine. J Pediatric Health Care. 2018;32(1):29–35. PubMed

Horne Z., et al. Countering antivaccination attitudes. Proc Natl Acad Sci U.S.A. 2015;112(33):10321–10324. PubMed PMC

Najít záznam

Citační ukazatele

Nahrávání dat ...

Možnosti archivace

Nahrávání dat ...