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Uncovering the Advantages of Foam Dressings with Active Ingredients

. 2025 May 22 ; 18 (6) : . [epub] 20250522

Status PubMed-not-MEDLINE Language English Country Switzerland Media electronic

Document type Journal Article

Background/Objectives: Foam dressings are designed for their ability to manage exudate and are selected to optimize wound repair. Various foam dressings are available, ranging from basic polyurethane to more sophisticated options, incorporating active components to combat infections or foster healing. This study investigates the requirements for the most suitable foam dressing through a combination of field research, laboratory testing, and clinical evaluation. Methods: We tested 17 foam dressings commonly used by wound care professionals while attending an international conference. An effective foam dressing should absorb wound fluid for several days, as wound care professionals value absorption and retention capacity, often favoring less frequent changing dressings, preferably twice a week or even weekly. Results: The foam dressings tested can absorb the expected amount of exudate typically produced by different wound types. There is some variability in retention capacity and product prices, resulting in differences in cost-effectiveness among products. In addition, some dressings are enriched with active ingredients that can accelerate healing through their antimicrobial and anti-inflammatory properties, such as foam dressings infused with silver or honey. A honey-based foam dressing was evaluated in a clinical survey involving eight wound care specialists, and four clinical cases with varying wound pathologies were discussed in more detail to highlight its key properties. Conclusions: Ideally, a foam dressing should have adequate absorption and retention capacities, effectively resolve and prevent infections, protect against external trauma, ensure optimal patient comfort without damaging newly formed granulation tissue, accelerate wound healing processes, and reduce wound care time (e.g., remaining in place for 7 days). Together, these factors make honey- or silver-loaded foam dressings more cost-effective than plain dressings due to their antimicrobial activities and ability to nourish tissues.

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Guo S., Dipietro L.A. Factors affecting wound healing. J. Dent. Res. 2010;89:219–229. doi: 10.1177/0022034509359125. PubMed DOI PMC

Winter G.D. Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig. Nature. 1962;193:293–294. doi: 10.1038/193293a0. PubMed DOI

Hinman C.D., Maibach H. Effect of Air Exposure and Occlusion on Experimental Human Skin Wounds. Nature. 1963;200:377–378. doi: 10.1038/200377a0. PubMed DOI

Junker J.P., Kamel R.A., Caterson E.J., Eriksson E. Clinical Impact Upon Wound Healing and Inflammation in Moist, Wet, and Dry Environments. Adv. Wound Care. 2013;2:348–356. doi: 10.1089/wound.2012.0412. PubMed DOI PMC

Swezey L. Moist Wound healing. Wound Educators. 2014. [(accessed on 13 March 2025)]. Available online: https://woundeducators.com/wound-moisture-balance/

Moore Z., Strapp H. Managing the problem of excess exudate. Br. J. Nurs. 2015;24:S14–S17. doi: 10.12968/bjon.2015.24.Sup15.S12. PubMed DOI

Jones M.L. An introduction to absorbent dressings. Br. J. Community Nurs. 2014;19:S28–S30. doi: 10.12968/bjcn.2014.19.Sup12.S28. PubMed DOI

Dowsett C. Moisture in wound healing: Exudate management. Br. J. Community Nurs. 2013;16((Suppl. S6)):S6–S12. doi: 10.12968/bjcn.2011.16.Sup6.S6. DOI

World Union of Wound Healing Societies (WUWHS) Consensus Document. Wound exudate: Effective assessment and management Wounds International. 2019. [(accessed on 13 March 2025)]. Available online: https://woundsinternational.com/world-union-resources/wuwhs-consensus-document-wound-exudate-effective-assessment-and-management/

Dabiri G., Damstetter E., Phillips T. Choosing a Wound Dressing Based on Common Wound Characteristics. Adv. Wound Care. 2016;5:32–41. doi: 10.1089/wound.2014.0586. PubMed DOI PMC

Britto E.J., Nezwek T.A., Popowicz P., Robins M. StatPearls. StatPearls Publishing; Treasure Island, FL, USA: 2025. Wound Dressings. PubMed

Sood A., Granick M.S., Tomaselli N.L. Wound Dressings and Comparative Effectiveness Data. Adv. Wound Care. 2014;3:511–529. doi: 10.1089/wound.2012.0401. PubMed DOI PMC

Nguyen H.M., Ngoc Le T.T., Nguyen A.T., Thien Le H.N., Pham T.T. Biomedical materials for wound dressing: Recent advances and applications. RSC Adv. 2023;13:5509–5528. doi: 10.1039/D2RA07673J. PubMed DOI PMC

Ovington L.G. Advances in wound dressings. Clin. Dermatol. 2007;25:33–38. doi: 10.1016/j.clindermatol.2006.09.003. PubMed DOI

ConvaTec Aquacel Ag Foam Adhesive Dressing Product Information. [(accessed on 13 March 2025)]. Available online: https://medisa.com.au/products/wound-care-basic-dressings-first-aid-dressing-convatec-aquacel-ag-foam-adhesive-dressing-all-sizes.

Choi H., Castillo B., Seminario-Vidal L. Silver absorption in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis treated with silver-impregnated dressings. A case series. Int. Wound J. 2018;15:1049–1051. doi: 10.1111/iwj.12938. PubMed DOI PMC

Allevyn Ag Product Information. [(accessed on 13 March 2025)]. Available online: https://www.smith-nephew.com/nl-be/health-care-professionals/products/advanced-wound-management/allevyn-ag-range.

Shih T., Park S., Thorlacius L.R., Daveluy S., Garg A., Goegji S.D., Kirby J.S., McGrath B.M., Riis P.T., Villumsen B., et al. Wound drainage measurements: A narrative review. Arch. Dermatol. Res. 2023;315:1863–1874. doi: 10.1007/s00403-023-02525-5. PubMed DOI PMC

Mulder G.D. Quantifying wound fluids for the clinician and researcher. Ostomy Wound Manag. 1994;40:66–69. PubMed

Dealey C., Cameron J., Arrowsmith M. A study comparing two objective methods of quantifying the production of wound exudate. J. Wound Care. 2006;15:149–153. doi: 10.12968/jowc.2006.15.4.26897. PubMed DOI

Cutting K.F., White R.J. Avoidance and management of peri-wound maceration of the skin. Prof. Nurse. 2002;18:35–36. PubMed

Romanelli M., Vowden K., Weir D. Exudate management made easy. Wounds Int. 2010;1:1–6.

Dowsett C., Ayello E. TIME principles of chronic wound bed preparation and treatment. Br. J. Nurs. 2004;13:S16–S23. doi: 10.12968/bjon.2004.13.Sup3.15546. PubMed DOI

Gefen A., Alves P., Beeckman D., Cullen B., Lazaro-Martinez J.L., Lev-Tov H., Santamaria N., Swanson T., Woo K., Soderstrom B., et al. Fluid handling by foam wound dressings: From engineering theory to advanced laboratory performance evaluations. Int. Wound J. 2024;21:e14674. doi: 10.1111/iwj.14674. PubMed DOI PMC

Nygren E., Malone M., Gefen A. Laboratory Evaluations of Wound Dressings: Key Advances to Reflect Clinical Reality. Int. Wound J. 2025;22((Suppl. S1)) doi: 10.1111/iwj.70333. PubMed DOI PMC

Pleeging C.C.F., Wagener F., de Rooster H., Cremers N.A.J. Revolutionizing non-conventional wound healing using honey by simultaneously targeting multiple molecular mechanisms. Drug Resist. Update. 2022;62:100834. doi: 10.1016/j.drup.2022.100834. PubMed DOI

Mandal M.D., Mandal S. Honey: Its medicinal property and antibacterial activity. Asian Pac. J. Trop. Biomed. 2011;1:154–160. doi: 10.1016/S2221-1691(11)60016-6. PubMed DOI PMC

Hermanns R., Mateescu C., Thrasyvoulou A., Tananaki C., Wagener F.A., Cremers N.A. Defining the standards for medical grade honey. J. Apic. Res. 2020;59:125–135. doi: 10.1080/00218839.2019.1693713. DOI

Spear M. Wound exudate--the good, the bad, and the ugly. Plast. Surg. Nurs. 2012;32:77–79. doi: 10.1097/PSN.0b013e318256d638. PubMed DOI

Vermeulen H., Ubbink D.T., Goossens A., de Vos R., Legemate D.A. Systematic review of dressings and topical agents for surgical wounds healing by secondary intention. Br. J. Surg. 2005;92:665–672. doi: 10.1002/bjs.5055. PubMed DOI

Lindholm C., Searle R. Wound management for the 21st century: Combining effectiveness and efficiency. Int. Wound J. 2016;13((Suppl. 2)):5–15. doi: 10.1111/iwj.12623. PubMed DOI PMC

Pleeging C.C.F., Coenye T., Mossialos D., de Rooster H., Chrysostomou D., Wagener F., Cremers N.A.J. Synergistic Antimicrobial Activity of Supplemented Medical-Grade Honey against Pseudomonas aeruginosa Biofilm Formation and Eradication. Antibiotics. 2020;9:866. doi: 10.3390/antibiotics9120866. PubMed DOI PMC

Oryan A., Alemzadeh E., Moshiri A. Biological properties and therapeutic activities of honey in wound healing: A narrative review and meta-analysis. J. Tissue Viability. 2016;25:98–118. doi: 10.1016/j.jtv.2015.12.002. PubMed DOI

Yildiz Karadeniz E., Kaplan Serin E. Use of honey in diabetic foot ulcer: Systematic review and meta-analysis. J. Tissue Viability. 2023;32:270–278. doi: 10.1016/j.jtv.2023.03.002. PubMed DOI

Yilmaz A.C., Aygin D. Honey Dressing in Wound Treatment: A Systematic Review. Complement. Ther. Med. 2020;51:102388. doi: 10.1016/j.ctim.2020.102388. PubMed DOI

Bocoum A., Riel S., Traore S.O., Ngo Oum Ii E.F., Traore Y., Thera A.T., Fane S., Dembele B.T., Cremers N.A.J. Medical-Grade Honey Enhances the Healing of Caesarean Section Wounds and Is Similarly Effective to Antibiotics Combined with Povidone-Iodine in the Prevention of Infections-A Prospective Cohort Study. Antibiotics. 2023;12:92. doi: 10.3390/antibiotics12010092. PubMed DOI PMC

Gustafsson K., Tatz A.J., Slavin R.A., Sutton G.A., Dahan R., Abu Ahmad W., Kelmer G. Intra-incisional medical grade honey decreases the prevalence of incisional infection in horses undergoing colic surgery: A prospective randomised controlled study. Equine Vet. J. 2020;53:1112–1118. doi: 10.1111/evj.13407. PubMed DOI

Mandel H.H., Sutton G.A., Abu E., Kelmer G. Intralesional application of medical grade honey improves healing of surgically treated lacerations in horses. Equine Vet. J. 2020;52:41–45. doi: 10.1111/evj.13111. PubMed DOI

Boekema B.K., Pool L., Ulrich M.M. The effect of a honey based gel and silver sulphadiazine on bacterial infections of in vitro burn wounds. Burns. 2013;39:754–759. doi: 10.1016/j.burns.2012.09.008. PubMed DOI

Boekema B., Chrysostomou D., Ciprandi G., Elgersma A., Vlig M., Pokorna A., Peters L.J.F., Cremers N.A.J. Comparing the antibacterial and healing properties of medical-grade honey and silver-based wound care products in burns. Burns. 2024;50:597–610. doi: 10.1016/j.burns.2023.10.009. PubMed DOI

Khansa I., Schoenbrunner A.R., Kraft C.T., Janis J.E. Silver in Wound Care-Friend or Foe?: A Comprehensive Review. Plast. Reconstr. Surg. Glob. Open. 2019;7:e2390. doi: 10.1097/GOX.0000000000002390. PubMed DOI PMC

Test Methods for Wound Dressings—Aspects of Absorption, Moisture Vapour Transmission, Waterproofness and Extensibility. Royal Dutch Standardisation Institute (NEN); Delft, the Netherlands: Sep 1, 2023. [(accessed on 10 February 2025)]. Available online: https://www.nen.nl/nen-en-13726-2023-en-315671.

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