A consensus guide to preclinical indirect calorimetry experiments
Jazyk angličtina Země Německo Médium print-electronic
Typ dokumentu časopisecké články, přehledy
Grantová podpora
P30 DK116074
NIDDK NIH HHS - United States
R01 DK125260
NIDDK NIH HHS - United States
PubMed
40993210
DOI
10.1038/s42255-025-01360-4
PII: 10.1038/s42255-025-01360-4
Knihovny.cz E-zdroje
- MeSH
- energetický metabolismus MeSH
- konsensus MeSH
- lidé MeSH
- nepřímá kalorimetrie * normy metody MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
Understanding the complex factors influencing mammalian metabolism and body weight homeostasis is a long-standing challenge requiring knowledge of energy intake, absorption and expenditure. Using measurements of respiratory gas exchange, indirect calorimetry can provide non-invasive estimates of whole-body energy expenditure. However, inconsistent measurement units and flawed data normalization methods have slowed progress in this field. This guide aims to establish consensus standards to unify indirect calorimetry experiments and their analysis for more consistent, meaningful and reproducible results. By establishing community-driven standards, we hope to facilitate data comparison across research datasets. This advance will allow the creation of an in-depth, machine-readable data repository built on shared standards. This overdue initiative stands to markedly improve the accuracy and depth of efforts to interrogate mammalian metabolism. Data sharing according to established best practices will also accelerate the translation of basic findings into clinical applications for metabolic diseases afflicting global populations.
American Federation for Aging Research New York NY USA
Broad Institute of Harvard and MIT Cambridge MA USA
Cambridge Heart and Lung Research Institute Cambridge UK
Cambridge University Nanjing Centre of Technology and Innovation Nanjing PR China
Cardiovascular Center Medical College of Wisconsin Milwaukee WI USA
Cardiovascular Research Institute Weill Cornell Medicine New York NY USA
Center for Genomic Medicine Massachusetts General Hospital Harvard Medical School Boston MA USA
Centre de Recherche du Centre Hospitalier de l'Université de Montréal Montreal Quebec Canada
Centre for Experimental Medicine Institute for Clinical and Experimental Medicine Prague Czechia
Centre for Metabolism Obesity and Diabetes Research McMaster University Hamilton Ontario Canada
Centro de Investigacion Principe Felipe Valencia Spain
Centro de Investigación Principe Felipe Valencia Spain
Comprehensive Rodent Metabolic Phenotyping Core Medical College of Wisconsin Milwaukee WI USA
Department of Anatomy University of California San Francisco San Francisco CA USA
Department of Biochemistry and Microbiology University of Chemistry and Technology Prague Czechia
Department of Biochemistry and Molecular Biology Monash University Clayton Victoria Australia
Department of Biochemistry McGill University Montreal Quebec Canada
Department of Biology University of Alabama at Birmingham Birmingham AL USA
Department of Biomedical Engineering Medical College of Wisconsin Milwaukee WI USA
Department of Cancer Biology Dana Farber Cancer Institute Boston MA USA
Department of Cell Biology and Physiology University of Kansas Medical Center Kansas City KS USA
Department of Cell Biology Harvard University Medical School Boston MA USA
Department of Cellular and Molecular Physiology Yale School of Medicine New Haven CT USA
Department of Health Sciences and Technology ETH Zurich Zurich Switzerland
Department of Integrative Physiology Baylor College of Medicine Houston TX USA
Department of Medicine Albert Einstein College of Medicine Bronx NY USA
Department of Medicine Baylor College of Medicine Houston TX USA
Department of Medicine The University of Chicago Chicago IL USA
Department of Medicine Université de Montréal Montreal Quebec Canada
Department of Molecular and Cellular Biology Baylor College of Medicine Houston TX USA
Department of Molecular and Integrative Physiology University of Michigan Ann Arbor MI USA
Department of Molecular Biosciences University of California Davis Davis CA USA
Department of Neuroscience Albert Einstein College of Medicine Bronx NY USA
Department of Obstetrics and Gynecology University of Michigan Ann Arbor MI USA
Department of Pathology Stanford University School of Medicine Stanford CA USA
Department of Physiology Medical College of Wisconsin Milwaukee WI USA
Department of Physiology Perelman School of Medicine University of Pennsylvania Philadelphia PA USA
Department of Surgery School of Medicine University of California Davis Davis CA USA
Diabetes Center University of California San Francisco San Francisco CA USA
Division of Cardiology Department of Medicine Weill Cornell Medicine New York NY USA
Division of Diabetes Endocrinology and Metabolism Baylor College of Medicine Houston TX USA
Faculty of Medicine and Health UNSW Sydney Sydney New South Wales Australia
German Center for Diabetes Research Neuherberg Germany
Harold Hamm Diabetes Center University of Oklahoma Health Sciences Oklahoma City OK USA
Institute for Diabetes and Obesity Helmholtz Munich Munich Germany
Institute of Experimental Genetics German Mouse Clinic Helmholtz Zentrum Munich Germany
Institute of Genetics and Developmental Biology Chinese Academy of Sciences Beijing China
Institute of Health Sciences China Medical University Shenyang China
KU Diabetes Institute Kansas City KS USA
Luxembourg Centre for Systems Biomedicine University of Luxembourg Luxembourg Luxembourg
Monash Biomedicine Discovery Institute Monash University Clayton Victoria Australia
Mouse Biology Program University of California Davis Davis CA USA
MRC Institute of Metabolic Science and Medical Research Council Cambridge UK
Obesity and Comorbidities Research Center University of Campinas Campinas Brazil
Pennington Biomedical Research Center Louisiana State University Baton Rouge LA USA
Pennington Biomedical Research Center LSU System Baton Rouge LA USA
Rosalind and Morris Goodman Cancer Institute McGill University Montreal Quebec Canada
School of Biological Sciences University of Aberdeen Aberdeen UK
School of Life and Environmental Sciences The University of Sydney Sydney New South Wales Australia
School of Life Sciences Fudan University Shanghai China
School of Medical Sciences The University of Sydney Sydney New South Wales Australia
Stanford Cardiovascular Institute Stanford University School of Medicine Stanford CA USA
Stanford Diabetes Research Center Stanford University School of Medicine Stanford CA USA
The Charles Perkins Centre The University of Sydney Sydney New South Wales Australia
The Jackson Laboratory Bar Harbor ME USA
Touchstone Diabetes Center University of Texas Southwestern Medical Center Dallas TX USA
Translational Gerontology Branch National Institute on Aging NIH Baltimore MD USA
University of Washington Medicine Diabetes Institute Department of Medicine Seattle WA USA
VA Greater Los Angeles Healthcare System GRECC Los Angeles CA USA
Vanderbilt Mouse Metabolic Phenotyping Center Vanderbilt University Nashville TN USA
Victor Chang Cardiac Research Institute Darlinghurst New South Wales Australia
Weill Center for Metabolic Health Weill Cornell Medicine New York NY USA
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