Ataxins [ataxiny]

topical
2
Terms

proteiny při spinocerebelární ataxii

 

Ataxin
Ataxin Protein
Ataxin Proteins
Spinocerebellar Ataxia Protein
Spinocerebellar Ataxia Proteins

Persistent link   https://www.medvik.cz/link/D000067528
Definition

A family of predominantly nuclear proteins that regulate gene transcription and protein degradation. The expansion of CAG trinucleotide repeats in genes that encode Ataxins is associated with SPINOCEREBELLAR ATAXIAS (SCA). In SCA patients, the number of CAG repeats correlates with the severity of disease and inversely correlates with the age of disease onset.

DUI
D000067528 MeSH Browser
CUI
M000599991
Previous indexing
Nerve Tissue Proteins (1995-2015); Nuclear Proteins (1995-2015)
History note
2016
Public note
2016

Allowable subheadings

AD
administration & dosage 0
AE
adverse effects 1
AG
agonists 0
AN
analysis 0
AI
antagonists & inhibitors 0
BI
biosynthesis 0
BL
blood 0
CF
cerebrospinal fluid 0
CS
chemical synthesis 0
CH
chemistry 0
CL
classification 0
DF
deficiency 0
DE
drug effects 0
EC
economics 0
GE
genetics 0
HI
history 0
IM
immunology 0
IP
isolation & purification 2
ME
metabolism 0
PK
pharmacokinetics 0
PD
pharmacology 0
PH
physiology 0
PO
poisoning 0
RE
radiation effects 0
ST
standards 0
SD
supply & distribution 0
TU
therapeutic use 0
TO
toxicity 0
UL
ultrastructure 0
UR
urine 0

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 575
D12.776.631 Nerve Tissue Proteins 263
D12.776.631.024 Acid Sensing Ion Channels 2
D12.776.631.050 Agrin
D12.776.631.069 Ataxins 2
D12.776.631.069.500 Ataxin-1 2
D12.776.631.069.750 Ataxin-2
D12.776.631.069.875 Ataxin-3 1
D12.776.631.069.901 Ataxin-7
D12.776.631.069.950 Ataxin-10
D12.776.631.087 Calbindin 1
D12.776.631.124 Chimerin Proteins 2
D12.776.631.199 Chromogranins 25
D12.776.631.212 Collapsin Response Mediator Protein 1
D12.776.631.224 Disks Large Homolog 4 Protein 1
D12.776.631.249 Dopamine and cAMP-Regulated Phosphoprotein 32 3
D12.776.631.262 Dysbindin
D12.776.631.274 Fatty Acid-Binding Protein 7 1
D12.776.631.299 Fragile X Mental Retardation Protein 7
D12.776.631.400 GAP-43 Protein 5
D12.776.631.480 Glucose Transporter Type 3
D12.776.631.520 ELAV Proteins 2
D12.776.631.530 Homeobox Protein SIX3
D12.776.631.540 Metallothionein 3 1
D12.776.631.560 Microtubule-Associated Proteins 101
D12.776.631.580 Myelin Proteins 32
D12.776.631.590 Natriuretic Peptide, Brain 346
D12.776.631.600 Nerve Growth Factors 70
D12.776.631.607 Nestin 17
D12.776.631.609 Neurexins
D12.776.631.611 Neuro-Oncological Ventral Antigen
D12.776.631.615 Neuroendocrine Secretory Protein 7B2
D12.776.631.630 Neurofilament Proteins 51
D12.776.631.635 Neuroglobin
D12.776.631.640 Neurogranin 1
D12.776.631.641 Neuroligins
D12.776.631.642 Neuronal Apoptosis-Inhibitory Protein
D12.776.631.645 Neuronal Calcium-Sensor Proteins 1
D12.776.631.650 Neuropeptides 202
D12.776.631.651 Nogo Receptors
D12.776.631.653 Olfactory Marker Protein
D12.776.631.654 Oligodendrocyte Transcription Factor 2
D12.776.631.656 Rabphilin-3A
D12.776.631.658 S100 Proteins 133
D12.776.631.703 SAP90-PSD95 Associated Proteins
D12.776.631.727 Slit Homolog 2 Protein
D12.776.631.750 Synapsins 2
D12.776.631.775 Synaptogyrins 1
D12.776.631.800 Synaptophysin 10
D12.776.631.860 Synucleins 3
D12.776.631.920 Tubulin 160
D12.776.631.960 Voltage-Gated Sodium Channels 6
D12.776.660 Nuclear Proteins 452
D12.776.660.049 Antennapedia Homeodomain Protein 1
D12.776.660.075 Ataxins 2
D12.776.660.075.500 Ataxin-1 2
D12.776.660.075.750 Ataxin-2
D12.776.660.075.875 Ataxin-3 1
D12.776.660.075.900 Ataxin-7
D12.776.660.100 BRCA1 Protein 101
D12.776.660.105 BRCA2 Protein 95
D12.776.660.167 CCAAT-Enhancer-Binding Proteins 11
D12.776.660.201 CDX2 Transcription Factor 3
D12.776.660.235 Chromosomal Proteins, Non-Histone 93
D12.776.660.264 Fanconi Anemia Complementation Group A Protein 1
D12.776.660.285 Fanconi Anemia Complementation Group D2 Protein 4
D12.776.660.289 Fanconi Anemia Complementation Group E Protein
D12.776.660.293 Fanconi Anemia Complementation Group F Protein
D12.776.660.323 Fanconi Anemia Complementation Group N Protein 4
D12.776.660.338 GADD45 Proteins
D12.776.660.352 Hepatocyte Nuclear Factors 5
D12.776.660.415 Homeobox Protein Nkx-2.2
D12.776.660.478 Host Cell Factor C1 2
D12.776.660.486 Immunoglobulin J Recombination Signal Sequence-Binding Protein
D12.776.660.494 Inhibitor of Growth Protein 1
D12.776.660.502 Karyopherins 9
D12.776.660.526 Mad2 Proteins 1
D12.776.660.551 Mediator Complex 5
D12.776.660.600 NF-kappa B 215
D12.776.660.625 Antigens, Nuclear 11
D12.776.660.650 Nuclear Matrix-Associated Proteins 2
D12.776.660.675 Nuclear Receptor Coactivators 6
D12.776.660.688 Nuclear Receptor Interacting Protein 1 3
D12.776.660.691 Nucleolin
D12.776.660.694 Nucleophosmin 17
D12.776.660.700 Oncogene Protein p55(v-myc) 1
D12.776.660.720 Poly-ADP-Ribose Binding Proteins 5
D12.776.660.740 Proliferating Cell Nuclear Antigen 60
D12.776.660.745 Promyelocytic Leukemia Protein 4
D12.776.660.750 Protamines 42
D12.776.660.760 Proto-Oncogene Proteins c-fos 61
D12.776.660.763 Proto-Oncogene Proteins c-jun 17
D12.776.660.764 Proto-Oncogene Proteins c-mdm2 65
D12.776.660.765 Proto-Oncogene Proteins c-myc 66
D12.776.660.767 Proto-Oncogene Proteins c-rel 2
D12.776.660.768 ran GTP-Binding Protein 4
D12.776.660.769 Retinoblastoma Binding Proteins 3
D12.776.660.770 Retinoblastoma-Like Protein p107 4
D12.776.660.794 Retinoblastoma-Like Protein p130 5
D12.776.660.807 Retinoblastoma Protein 52
D12.776.660.820 Silent Information Regulator Proteins, Saccharomyces cerevisiae
D12.776.660.823 Thyroid Nuclear Factor 1
D12.776.660.912 Tumor Protein p73 6

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