Discoidin Domain Receptors [receptory diskoidinové domény]

topical
Terms

DDR proteiny
discoidin doménový receptor
receptor diskoidinové domény
receptory discoidinové domény

 

DDR Proteins
Discoidin Domain Receptor

Definition

Receptor tyrosine kinases that bind COLLAGENS. They are characterized by the presence of extracellular DISCOIDIN DOMAINS that activate SIGNAL TRANSDUCTION PATHWAYS in response to collagen binding. They may also be cleaved by MATRIX METALLOPROTEINASES to mediate cell interactions with the EXTRACELLULAR MATRIX.

DUI
D000070818 MeSH Browser
CUI
M0134195
History note
2017 (1999)
Public note
2017; DISCOIDIN DOMAIN RECEPTORS was indexed under RECEPTORS, MITOGEN and RECEPTOR PROTEIN-TYROSINE KINASES 1999-2016

D Chemicals and Drugs
D08.811 Enzymes 1 551
D08.811.913 Transferases 72
D08.811.913.696 Phosphotransferases 69
D08.811.913.696.620.682 Protein Kinases 249
D08.811.913.696.620.682.725 Protein-Tyrosine Kinases 622
D08.811.913.696.620.682.725.400 Receptor Protein-Tyrosine Kinases 154
D08.811.913.696.620.682.725.400.002 Anaplastic Lymphoma Kinase 87
D08.811.913.696.620.682.725.400.003 c-Mer Tyrosine Kinase 2
D08.811.913.696.620.682.725.400.005 Discoidin Domain Receptors
D08.811.913.696.620.682.725.400.005.500 Discoidin Domain Receptor 1
D08.811.913.696.620.682.725.400.005.750 Discoidin Domain Receptor 2 2
D08.811.913.696.620.682.725.400.009 ErbB Receptors 800
D08.811.913.696.620.682.725.400.020 fms-Like Tyrosine Kinase 3 53
D08.811.913.696.620.682.725.400.050 Proto-Oncogene Proteins c-kit 77
D08.811.913.696.620.682.725.400.075 Proto-Oncogene Proteins c-met 30
D08.811.913.696.620.682.725.400.087 Proto-Oncogene Proteins c-ret 42
D08.811.913.696.620.682.725.400.093 Receptor Tyrosine Kinase-like Orphan Receptors 9
D08.811.913.696.620.682.725.400.177 Receptor, Fibroblast Growth Factor, Type 1 11
D08.811.913.696.620.682.725.400.178 Receptor, Fibroblast Growth Factor, Type 2 3
D08.811.913.696.620.682.725.400.179 Receptor, Fibroblast Growth Factor, Type 3 28
D08.811.913.696.620.682.725.400.180 Receptor, Fibroblast Growth Factor, Type 4 3
D08.811.913.696.620.682.725.400.185 Receptor, IGF Type 1 43
D08.811.913.696.620.682.725.400.200 Receptor, Insulin 69
D08.811.913.696.620.682.725.400.500 Receptor, Macrophage Colony-Stimulating Factor 1
D08.811.913.696.620.682.725.400.660 Receptor, trkA 15
D08.811.913.696.620.682.725.400.700 Receptor, trkB 8
D08.811.913.696.620.682.725.400.800 Receptor, trkC 16
D08.811.913.696.620.682.725.400.850 Receptors, Eph Family 1
D08.811.913.696.620.682.725.400.900 Receptors, Platelet-Derived Growth Factor 33
D08.811.913.696.620.682.725.400.925 Receptors, TIE 5
D08.811.913.696.620.682.725.400.950 Receptors, Vascular Endothelial Growth Factor 350
D08.811.913.696.620.682.725.400.975 Axl Receptor Tyrosine Kinase
D12.776 Proteins 2 581
D12.776.476.568 Protein-Tyrosine Kinases 622
D12.776.476.568.400 Receptor Protein-Tyrosine Kinases 154
D12.776.476.568.400.002 Anaplastic Lymphoma Kinase 87
D12.776.476.568.400.003 c-Mer Tyrosine Kinase 2
D12.776.476.568.400.005 Discoidin Domain Receptors
D12.776.476.568.400.005.500 Discoidin Domain Receptor 1
D12.776.476.568.400.005.750 Discoidin Domain Receptor 2 2
D12.776.476.568.400.009 ErbB Receptors 800
D12.776.476.568.400.020 fms-Like Tyrosine Kinase 3 53
D12.776.476.568.400.050 Proto-Oncogene Proteins c-kit 77
D12.776.476.568.400.075 Proto-Oncogene Proteins c-met 30
D12.776.476.568.400.087 Proto-Oncogene Proteins c-ret 42
D12.776.476.568.400.185 Receptor, IGF Type 1 43
D12.776.476.568.400.200 Receptor, Insulin 69
D12.776.476.568.400.660 Receptor, trkA 15
D12.776.476.568.400.700 Receptor, trkB 8
D12.776.476.568.400.800 Receptor, trkC 16
D12.776.476.568.400.850 Receptors, Eph Family 1
D12.776.476.568.400.925 Receptors, TIE 5
D12.776.476.568.400.975 Axl Receptor Tyrosine Kinase
D12.776.543 Membrane Proteins 850
D12.776.543.750 Receptors, Cell Surface 511
D12.776.543.750.630 Receptor Protein-Tyrosine Kinases 154
D12.776.543.750.630.002 Anaplastic Lymphoma Kinase 87
D12.776.543.750.630.003 c-Mer Tyrosine Kinase 2
D12.776.543.750.630.005 Discoidin Domain Receptors
D12.776.543.750.630.005.500 Discoidin Domain Receptor 1
D12.776.543.750.630.005.750 Discoidin Domain Receptor 2 2
D12.776.543.750.630.009 ErbB Receptors 800
D12.776.543.750.630.020 fms-Like Tyrosine Kinase 3 53
D12.776.543.750.630.124 Proto-Oncogene Proteins c-kit 77
D12.776.543.750.630.186 Proto-Oncogene Proteins c-met 30
D12.776.543.750.630.217 Proto-Oncogene Proteins c-ret 42
D12.776.543.750.630.468 Receptor, IGF Type 1 43
D12.776.543.750.630.484 Receptor, Insulin 69
D12.776.543.750.630.496 Receptor, trkA 15
D12.776.543.750.630.498 Receptor, trkB 8
D12.776.543.750.630.499 Receptor, trkC 16
D12.776.543.750.630.500 Receptors, Eph Family 1
D12.776.543.750.630.687 Receptors, TIE 5
D12.776.543.750.630.875 Axl Receptor Tyrosine Kinase
D12.776.543.750.685 Receptors, Collagen
D12.776.543.750.685.050 Discoidin Domain Receptors
D12.776.543.750.685.050.500 Discoidin Domain Receptor 1
D12.776.543.750.685.050.750 Discoidin Domain Receptor 2 2
D12.776.543.750.685.100 Integrin alpha1beta1
D12.776.543.750.685.200 Integrin alpha2beta1 3
D12.776.543.750.685.300 Integrin alpha3beta1 1
D12.776.543.750.705 Receptors, Immunologic 129
D12.776.543.750.705.880 Receptors, Mitogen 7
D12.776.543.750.705.880.300 Discoidin Domain Receptors
D12.776.543.750.705.880.300.500 Discoidin Domain Receptor 1
D12.776.543.750.705.880.300.750 Discoidin Domain Receptor 2 2
D12.776.543.750.705.880.600 Receptors, Concanavalin A 1