Integrin alpha1beta1 functions as a receptor for LAMININ and COLLAGEN. It is widely expressed during development, but in the adult is the predominant laminin receptor (RECEPTORS, LAMININ) in mature SMOOTH MUSCLE CELLS, where it is important for maintenance of the differentiated phenotype of these cells. Integrin alpha1beta1 is also found in LYMPHOCYTES and microvascular endothelial cells, and may play a role in angiogenesis. In SCHWANN CELLS and neural crest cells, it is involved in cell migration. Integrin alpha1beta1 is also known as VLA-1 and CD49a-CD29.

DUI

D039222 MeSH Prohlížeč

CUI

M0230961

Předchozí užití

Integrins (1994-2002)

Historická pozn.

2003; use INTEGRIN ALPHA1BETA1 (NM) 1994-2002

Veřejná pozn.

2003; INTEGRIN ALPHA1BETA1 was indexed under INTEGRINS 1994-2002