Integrin alpha6beta4 [integrin alfa6beta4]
- Terms
-
A9 Antigen
alpha(6)beta(4) Epithelial Integrin
alpha(6)beta(4) Integrin
alpha6 beta4 Integrin
Integrin alpha(6),beta(4)
Laminin-5 Receptor (alpha6beta4 Integrin)
TSP-180
Tumor Specific Protein-180 Complex
This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenance in epithelial cells. Integrin alpha6beta4 is also found on thymocytes, fibroblasts, and Schwann cells, where it functions as a laminin receptor (RECEPTORS, LAMININ) and is involved in wound healing, cell migration, and tumor invasiveness.
- DUI
- D039161 MeSH Browser
- CUI
- M0154541
- Previous indexing
- Antigens, Surface (1988-2002); Integrins (1988-2002)
- History note
- 2003; use INTEGRIN ALPHA6BETA4 (NM) 1988-2002
- Public note
- 2003; INTEGRIN ALPHA6BETA4 was indexed under INTEGRINS; & ANTIGENS, SURFACE 1988-2002.
Allowable subheadings
- AD
- administration & dosage
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PH
- physiology
- RE
- radiation effects
- TU
- therapeutic use
- UL
- ultrastructure