Integrin alpha2beta1 [integrin alfa2beta1]

topical
3
Terms

alpha2beta1Integrin
CD49b-CD29
Glycoprotein Ia-IIa
Platelet Membrane Glycoprotein Heterodimer Ia-IIa
Very Late Antigen-2
VLA-2

Persistent link   https://www.medvik.cz/link/D038982
Definition

An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase.

DUI
D038982 MeSH Browser
CUI
M0417889
Previous indexing
Integrins (1994-2002); Collagen Receptors (1991-2002)
History note
2003; for VLA-2 use COLLAGEN RECEPTORS (NM) 1991-2002; for PLATELET MEMBRANE GLYCOPROTEIN HETERODIMER IA-IIA use COLLAGEN RECEPTORS (NM) 1992-2000; for INTEGRIN ALPHA2BETA1 & CD49B-CD29 use COLLAGEN RECEPTORS (NM) 1994-2002; for ALPHA2BETA1INTEGRIN use COLLAGEN RECEPTORS (NM) 2001-2002
Public note
2003; INTEGRIN ALPHA2BETA1 was indexed under INTEGRINS 1994-2002

Allowable subheadings

AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood 1
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics 1
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 1
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure

D Chemicals and Drugs
D09 Carbohydrates 723
D09.400 Glycoconjugates 58
D09.400.430 Glycoproteins 637
D09.400.430.890 Membrane Glycoproteins 200
D09.400.430.890.625 Platelet Membrane Glycoproteins 33
D09.400.430.890.625.136 CD36 Antigens 51
D09.400.430.890.625.298 Integrin alpha2beta1 3
D09.400.430.890.625.379 Integrin alpha5beta1 3
D09.400.430.890.625.419 Integrin alpha6beta1
D09.400.430.890.625.439 Integrin alphaVbeta3 7
D09.400.430.890.625.449 Lysosomal-Associated Membrane Protein 1 3
D09.400.430.890.625.460 Platelet Glycoprotein GPIb-IX Complex 8
D09.400.430.890.625.785 Platelet Glycoprotein GPIIb-IIIa Complex 93
D09.400.430.890.625.800 Receptors, Thrombin 14
D09.400.430.890.625.905 P-Selectin 43
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 577
D12.776.395 Glycoproteins 637
D12.776.395.550 Membrane Glycoproteins 200
D12.776.395.550.625 Platelet Membrane Glycoproteins 33
D12.776.395.550.625.136 CD36 Antigens 51
D12.776.395.550.625.298 Integrin alpha2beta1 3
D12.776.395.550.625.379 Integrin alpha5beta1 3
D12.776.395.550.625.419 Integrin alpha6beta1
D12.776.395.550.625.439 Integrin alphaVbeta3 7
D12.776.395.550.625.449 Lysosomal-Associated Membrane Protein 1 3
D12.776.395.550.625.460 Platelet Glycoprotein GPIb-IX Complex 8
D12.776.395.550.625.785 Platelet Glycoprotein GPIIb-IIIa Complex 93
D12.776.395.550.625.800 Receptors, Thrombin 14
D12.776.395.550.625.905 P-Selectin 43
D12.776.543 Membrane Proteins 849
D12.776.543.550 Membrane Glycoproteins 200
D12.776.543.550.625 Platelet Membrane Glycoproteins 33
D12.776.543.550.625.136 CD36 Antigens 51
D12.776.543.550.625.298 Integrin alpha2beta1 3
D12.776.543.550.625.379 Integrin alpha5beta1 3
D12.776.543.550.625.419 Integrin alpha6beta1
D12.776.543.550.625.439 Integrin alphaVbeta3 7
D12.776.543.550.625.449 Lysosomal-Associated Membrane Protein 1 3
D12.776.543.550.625.460 Platelet Glycoprotein GPIb-IX Complex 8
D12.776.543.550.625.785 Platelet Glycoprotein GPIIb-IIIa Complex 93
D12.776.543.550.625.800 Receptors, Thrombin 14
D12.776.543.550.625.905 P-Selectin 43
D12.776.543.750 Receptors, Cell Surface 511
D12.776.543.750.685 Receptors, Collagen
D12.776.543.750.685.050 Discoidin Domain Receptors
D12.776.543.750.685.100 Integrin alpha1beta1
D12.776.543.750.685.200 Integrin alpha2beta1 3
D12.776.543.750.685.300 Integrin alpha3beta1 1
D12.776.543.750.705 Receptors, Immunologic 129
D12.776.543.750.705.408 Integrins 118
D12.776.543.750.705.408.530 Receptors, Fibronectin 2
D12.776.543.750.705.408.530.249 Integrin alpha2beta1 3
D12.776.543.750.705.408.530.500 Integrin alpha4beta1 5
D12.776.543.750.705.408.530.750 Integrin alpha5beta1 3
D12.776.543.750.705.408.850 Receptors, Very Late Antigen
D12.776.543.750.705.408.850.099 Integrin alpha1beta1
D12.776.543.750.705.408.850.199 Integrin alpha2beta1 3
D12.776.543.750.705.408.850.249 Integrin alpha3beta1 1
D12.776.543.750.705.408.850.299 Integrin alpha4beta1 5
D12.776.543.750.705.408.850.349 Integrin alpha5beta1 3
D12.776.543.750.705.408.850.674 Integrin alpha6beta1
D12.776.543.750.705.675 Platelet Membrane Glycoproteins 33
D12.776.543.750.705.675.136 CD36 Antigens 51
D12.776.543.750.705.675.352 Integrin alpha2beta1 3
D12.776.543.750.705.675.460 Integrin alpha5beta1 3
D12.776.543.750.705.675.514 Integrin alpha6beta1
D12.776.543.750.705.675.541 Integrin alphaVbeta3 7
D12.776.543.750.705.675.554 Lysosomal-Associated Membrane Protein 1 3
D12.776.543.750.705.675.568 Platelet Glycoprotein GPIb-IX Complex 8
D12.776.543.750.705.675.784 Platelet Glycoprotein GPIIb-IIIa Complex 93
D12.776.543.750.705.675.892 Receptors, Thrombin 14
D12.776.543.750.705.876 Receptors, Laminin 1
D12.776.543.750.705.876.249 Integrin alpha1beta1
D12.776.543.750.705.876.280 Integrin alpha2beta1 3
D12.776.543.750.705.876.311 Integrin alpha3beta1 1
D12.776.543.750.705.876.374 Integrin alpha5beta1 3
D12.776.543.750.705.876.500 Integrin alpha6beta1
D12.776.543.750.705.876.750 Integrin alpha6beta4

type I collagen receptor Chemical MeSH Browser

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