Discoidin Domain [diskoidinová doména]

topical
Terms

diskoidinové domény

 

Discoidin Domains

Persistent link   https://www.medvik.cz/link/D000070822
Definition

A protein domain originally identified in DISCOIDINS. It occurs in a variety of unrelated proteins in multicellular organisms, where it recognizes different ligands with distinct biological functions. Structurally, it consists of two antiparallel beta sheets that form a "jellyroll" configuration stabilized by two intramolecular disulfide bonds. Sequence differences within this module determine ligand specificity; in DISCOIDIN DOMAIN RECEPTORS, it binds to FIBRILLAR COLLAGENS and NON-FIBRILLAR COLLAGENS.

DUI
D000070822 MeSH Browser
CUI
M000612305
Previous indexing
Lectins (1998-2016); Protein Structure, Tertiary (1998-2016)
History note
2017
Public note
2017

Allowable subheadings

DE
drug effects 0
GE
genetics 0
IM
immunology 0
PH
physiology 0
RE
radiation effects 0

G Phenomena and Processes
G01 Physical Phenomena 75
G02 Chemical Phenomena 307
G02.111 Biochemical Phenomena 370
G02.111.570 Molecular Structure 1 313
G02.111.570.820 Molecular Conformation 228
G02.111.570.820.709 Protein Conformation 556
G02.111.570.820.709.275 Protein Structural Elements 1
G02.111.570.820.709.275.750 Protein Domains 178
G02.111.570.820.709.275.750.125 C2 Domains
G02.111.570.820.709.275.750.157 Carbohydrate Binding Modules
G02.111.570.820.709.275.750.188 Catalytic Domain 217
G02.111.570.820.709.275.750.219 Discoidin Domain
G02.111.570.820.709.275.750.235 HMG-Box Domains 2
G02.111.570.820.709.275.750.250 Immunoglobulin Domains 4
G02.111.570.820.709.275.750.375 Kringles 2
G02.111.570.820.709.275.750.438 Methyl CpG Binding Domain
G02.111.570.820.709.275.750.469 Pleckstrin Homology Domains 2
G02.111.570.820.709.275.750.477 PR-SET Domains
G02.111.570.820.709.275.750.485 Proline-Rich Protein Domains 3
G02.111.570.820.709.275.750.500 Protein Interaction Domains and Motifs 95
G03 Metabolic Phenomena obsolete
G04 Cell Physiological Phenomena 514
G05 Genetic Phenomena 133
G06 Microbiological Phenomena 95
G07 Physiological Phenomena 175
G08 Reproductive and Urinary Physiological Phenomena 18
G09 Circulatory and Respiratory Physiological Phenomena 94
G10 Digestive System and Oral Physiological Phenomena 4
G11 Musculoskeletal and Neural Physiological Phenomena 16
G12 Immune System Phenomena 248
G13 Integumentary System Physiological Phenomena 14
G14 Ocular Physiological Phenomena 147
G15 Plant Physiological Phenomena 158
G16 Biological Phenomena 129
G17 Mathematical Concepts 66

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