Carbonic Anhydrase IX [karboanhydrasa IX]
- Terms
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CAIX
karbonická anhydrasa IX
karbonická anhydráza IX
protein CAIX
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CAIX Protein
Carbonic Anhydrase 9
A carbonic anhydrase and transmembrane protein that consists of an N-terminal PROTEOGLYCAN-like domain, a catalytic region, a single-pass transmembrane domain, and a short intracellular tail. It functions as a dimer and is expressed primarily by cells of the GASTROINTESTINAL TRACT; BILE DUCT EPITHELIUM; and GALL BLADDER. It is expressed at high levels in many solid tumors, especially CLEAR CELL RENAL CARCINOMA, in response to CELL HYPOXIA.
- DUI
- D000071231 MeSH Browser
- CUI
- M000613753
- Previous indexing
- Antigens, Neoplasm (1994-2016); Carbonic Anhydrases (1994-2016)
- History note
- 2017
- Public note
- 2017
Allowable subheadings
- AD
- administration & dosage 1
- AE
- adverse effects
- AN
- analysis 2
- AI
- antagonists & inhibitors 7
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 5
- HI
- history
- IM
- immunology 3
- IP
- isolation & purification
- ME
- metabolism 11
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
CA9 protein, human Chemical MeSH Browser
Ca9 protein, rat Chemical MeSH Browser
Car9 protein, mouse Chemical MeSH Browser