AlkB Homolog 4, Lysine Demethylase [alfa-ketoglutarát-dependentní dioxygenasa, AlkB homolog 4]
- Terms
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alfa ketoglutarát dependentní dioxygenáza, AlkB homolog 4
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Alkylated DNA Repair Protein AlkB Homolog 4
Alpha-Ketoglutarate-Dependent Dioxygenase Alkb Homolog 4
A dioxygenase and alkylation repair homolog that mediates demethylation of ACTIN monomethylated at 'Lys-84' (K84me1). Demethylation of actin LYSINE 84 (K84me1) is required for maintaining actin and MYOSIN dynamics to support normal cleavage furrow ingression during CYTOKINESIS and CELL MIGRATION. It may also be involved in transcription regulation.
- DUI
- D000071501 MeSH Browser
- CUI
- M000614943
- Previous indexing
- Dioxygenases (2014-2016)
- History note
- 2017
- Public note
- 2017
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ALKBH4 protein, human Chemical MeSH Browser
ALKBH4 protein, mouse Chemical MeSH Browser