Tumor Suppressor p53-Binding Protein 1 [53BP1]
topical
16
- Terms
-
nádorově supresorový protein p53
tumor suppressor p53-binding protein 1
-
53BP1 Protein
p202 Protein
TP53BP1 Protein
Tumor Protein p53-Binding Protein, 1
Persistent link
https://www.medvik.cz/link/D000071857
Definition
A nuclear and cytoplasmic protein that associates with KINETOCHORES and contains a C-terminal TUDOR DOMAIN. It plays a critical role in the cellular response to DNA DAMAGE and localizes to DOUBLE-STRAND DNA BREAKS. It may also function in M PHASE CELL CYCLE CHECKPOINTS and as an enhancer of TUMOR SUPPRESSOR PROTEIN P53-mediated transcriptional activation.
- DUI
- D000071857 MeSH Browser
- CUI
- M000615636
- Previous indexing
- Intracellular Signaling Peptides and Proteins (2005-2016); Chromosomal Proteins, Non-Histone (2005-2016); DNA-Binding Proteins (2005-2016)
- History note
- 2017
- Public note
- 2017
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AG
- agonists 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 2
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 8
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 14
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs
D12.776.260.114
Butyrate Response Factor 1
D12.776.260.125
Centromere Protein B
D12.776.260.197
Elongin
D12.776.260.246
Factor For Inversion Stimulation Protein
D12.776.260.254
G-Box Binding Factors
D12.776.260.268
Heterogeneous-Nuclear Ribonucleoprotein K
D12.776.260.457
Immunoglobulin J Recombination Signal Sequence-Binding Protein
D12.776.260.495
Integration Host Factors
D12.776.260.513
Interferon-Stimulated Gene Factor 3
D12.776.260.527
Leucine-Responsive Regulatory Protein
D12.776.260.540
MutL Proteins
D12.776.260.556
MutS Proteins
D12.776.260.615
Nuclear Respiratory Factors
D12.776.260.650
Peptidyl-Prolyl Cis-Trans Isomerase NIMA-Interacting 4
D12.776.260.693
PTB-Associated Splicing Factor
D12.776.260.768
Transcription Factor MTF-1
D12.776.260.950
Winged-Helix Transcription Factors
D12.776.660.235.199
Centromere Protein B
D12.776.660.235.300
Chromobox Protein Homolog 5
D12.776.660.235.350
Cohesins
D12.776.660.235.675
Structural Maintenance of Chromosome Protein 1
D12.776.664.235.199
Centromere Protein B
D12.776.664.235.300
Chromobox Protein Homolog 5
D12.776.664.235.350
Cohesins
D12.776.664.235.925
Structural Maintenance of Chromosome Protein 1