Patched-1 Receptor [receptor Patched 1]
- Terms
-
Patched protein homolog 1
protein PTCH1
-
Patched Homolog-1
Patched Receptor-1
Patched-1 Protein
PTCH1 Protein
A patched receptor for several HEDGEHOG PROTEINS that associates with the SMOOTHENED RECEPTOR to modulate hedgehog signaling. It is also a TUMOR SUPPRESSOR PROTEIN; mutations in the patched-1 gene are associated with BASAL CELL NEVUS SYNDROME; SQUAMOUS CELL CARCNIOMA of the ESOPHAGUS; trichoepitheliomas, and CARCINOMA, TRANSITIONAL CELL of the URINARY BLADDER.
- DUI
- D000072081 MeSH Browser
- CUI
- M000616305
- History note
- 2017 (1996)
- Public note
- 2017; PATCHED-1 RECEPTOR was indexed under RECEPTORS, CELL SURFACE 2005-2016, and under MEMBRANE PROTEINS 1996-2005
Allowable subheadings
- AD
- administration & dosage
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- GE
- genetics 2
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 1
- PH
- physiology
- RE
- radiation effects
- TU
- therapeutic use
- UL
- ultrastructure
PTCH1 protein, human Chemical MeSH Browser
Ptch1 protein, mouse Chemical MeSH Browser
Ptch1 protein, rat Chemical MeSH Browser
ptc-1 protein, C elegans Chemical MeSH Browser