Niemann-Pick C1 Protein [protein NPC1]

topical
3
Terms

Niemannův-Pickův protein C1
transmembránový protein NPC1

 

NPC1 Protein

Persistent link   https://www.medvik.cz/link/D000077296
Definition

A transmembrane intracellular lipid transporter that helps trafficking lipids, particularly cholesterol, from late endosome/lysosome to the ER and plasma membrane. It may also play a role in other cellular cholesterol homeostasis and is an endosomal entry receptor for filoviruses including EBOLAVIRUS. Mutations in the NPC1 are associated with type C NIEMANN-PICK DISEASE.

DUI
D000077296 MeSH Browser
CUI
M000640362
Previous indexing
Carrier Proteins (1997-2018); Membrane Glycoproteins (1997-2018)
History note
2019
Public note
2019

Allowable subheadings

AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics 2
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 1
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 581
D12.776.157 Carrier Proteins 546
D12.776.157.530 Membrane Transport Proteins 207
D12.776.157.530.100 ATP-Binding Cassette Transporters 169
D12.776.157.530.200 Amino Acid Transport Systems 11
D12.776.157.530.300 Fatty Acid Transport Proteins 4
D12.776.157.530.400 Ion Channels 276
D12.776.157.530.450 Ion Pumps 25
D12.776.157.530.500 Monosaccharide Transport Proteins 21
D12.776.157.530.562 Neurotransmitter Transport Proteins 3
D12.776.157.530.594 Niemann-Pick C1 Protein 3
D12.776.157.530.625 Nucleobase, Nucleoside, Nucleotide, and Nucleic Acid Transport Proteins
D12.776.157.530.750 Nucleocytoplasmic Transport Proteins 8
D12.776.157.530.813 P-type ATPases
D12.776.157.530.875 SEC Translocation Channels 6
D12.776.157.530.937 Solute Carrier Proteins 7
D12.776.543 Membrane Proteins 850
D12.776.543.585 Membrane Transport Proteins 207
D12.776.543.585.100 ATP-Binding Cassette Transporters 169
D12.776.543.585.200 Amino Acid Transport Systems 11
D12.776.543.585.250 Connexins 53
D12.776.543.585.300 Fatty Acid Transport Proteins 4
D12.776.543.585.400 Ion Channels 276
D12.776.543.585.450 Ion Pumps 25
D12.776.543.585.475 Mitochondrial Membrane Transport Proteins 35
D12.776.543.585.500 Monosaccharide Transport Proteins 21
D12.776.543.585.562 Neurotransmitter Transport Proteins 3
D12.776.543.585.594 Niemann-Pick C1 Protein 3
D12.776.543.585.625 Nucleobase, Nucleoside, Nucleotide, and Nucleic Acid Transport Proteins
D12.776.543.585.750 Nucleocytoplasmic Transport Proteins 8
D12.776.543.585.813 P-type ATPases
D12.776.543.585.875 SEC Translocation Channels 6
D12.776.543.585.937 Solute Carrier Proteins 7
D12.776.543.750 Receptors, Cell Surface 511
D12.776.543.750.058 Patched Receptors
D12.776.543.750.058.250 Niemann-Pick C1 Protein 3
D12.776.543.750.058.500 Patched-1 Receptor 2
D12.776.543.750.058.750 Patched-2 Receptor
D12.776.543.750.830 Receptors, Virus 43
D12.776.543.750.830.062 Bacteriophage Receptors
D12.776.543.750.830.124 Coxsackie and Adenovirus Receptor-Like Membrane Protein
D12.776.543.750.830.187 Hepatitis A Virus Cellular Receptor 1
D12.776.543.750.830.219 Hepatitis A Virus Cellular Receptor 2 7
D12.776.543.750.830.235 Niemann-Pick C1 Protein 3
D12.776.543.750.830.250 Receptors, Complement 3d 2
D12.776.543.750.830.363 Receptors, Coronavirus 3
D12.776.543.750.830.475 Receptors, CXCR6
D12.776.543.750.830.700 Receptors, HIV 6
D12.776.543.750.830.850 Receptors, Tumor Necrosis Factor, Member 14
D12.776.543.750.830.925 Xenotropic and Polytropic Retrovirus Receptor
D12.776.624 Neoplasm Proteins 413
D12.776.624.776 Tumor Suppressor Proteins 269
D12.776.624.776.633 Patched Receptors
D12.776.624.776.633.250 Niemann-Pick C1 Protein 3
D12.776.624.776.633.500 Patched-1 Receptor 2
D12.776.624.776.633.750 Patched-2 Receptor

NPC1 protein, human Chemical MeSH Browser

NPC1 protein, rat Chemical MeSH Browser

NPC1 protein, zebrafish Chemical MeSH Browser

Npc1 protein, mouse Chemical MeSH Browser

Npc1a protein, Drosophila Chemical MeSH Browser

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