Loss of Function Mutation [mutace ztráty funkce]

topical
13
Terms

mutace způsobující ztrátu funkce
neúplná mutace
nulová mutace

 

Leaky Mutation
Null Mutation

Persistent link   https://www.medvik.cz/link/D000073658
Definition

A mutation that causes a decrease in or elimination of a gene product's activity.

DUI
D000073658 MeSH Browser
CUI
M000623325
Previous indexing
Mutation (1989-2017)
History note
2018
Public note
2018

Allowable subheadings

DE
drug effects
GE
genetics 5
IM
immunology
PH
physiology
RE
radiation effects

G Phenomena and Processes
G01 Physical Phenomena 81
G02 Chemical Phenomena 308
G03 Metabolism 1 203
G03 Metabolic Phenomena obsolete
G04 Cell Physiological Phenomena 515
G05 Genetic Phenomena 135
G05.365 Genetic Variation 864
G05.365.590 Mutation 5 073
G05.365.590.029 Allelic Imbalance 2
G05.365.590.060 Base Pair Mismatch 14
G05.365.590.175 Chromosome Aberrations 1 579
G05.365.590.195 Codon, Nonsense 52
G05.365.590.220 DNA Repeat Expansion 7
G05.365.590.265 Frameshift Mutation 47
G05.365.590.288 Gain of Function Mutation 18
G05.365.590.310 Gene Amplification 335
G05.365.590.320 Gene Duplication 65
G05.365.590.335 Genomic Instability 90
G05.365.590.350 Germ-Line Mutation 204
G05.365.590.500 INDEL Mutation 17
G05.365.590.538 Loss of Function Mutation 13
G05.365.590.575 Mutagenesis, Insertional 56
G05.365.590.594 Mutation Accumulation 3
G05.365.590.612 Mutation Rate 18
G05.365.590.650 Mutation, Missense 218
G05.365.590.675 Point Mutation 246
G05.365.590.762 Sequence Deletion 105
G05.365.590.770 Sequence Inversion 2
G05.365.590.803 Silent Mutation 2
G05.365.590.835 Suppression, Genetic 29
G05.365.590.917 Synthetic Lethal Mutations 4
G06 Microbiological Phenomena 96
G07 Physiological Phenomena 176
G08 Reproductive and Urinary Physiological Phenomena 18
G09 Circulatory and Respiratory Physiological Phenomena 93
G10 Digestive System and Oral Physiological Phenomena 4
G11 Musculoskeletal and Neural Physiological Phenomena 17
G12 Immune System Phenomena 249
G13 Integumentary System Physiological Phenomena 14
G14 Ocular Physiological Phenomena 148
G15 Plant Physiological Phenomena 158
G16 Biological Phenomena 130
G17 Mathematical Concepts 66

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