Triggering Receptor Expressed on Myeloid Cells-1 [receptor TREM-1]
- Terms
-
antigen CD354
TREM-1
-
CD354 Antigen
TREM-1 Protein
An approximately 230 amino acid membrane glycoprotein characterized by an IMMUNOGLOBULIN V-SET DOMAIN in its N-terminal half. It is expressed by MONOCYTES and NEUTROPHILS in response to INFLAMMATION related to bacterial and fungal infections. It triggers the release of pro-inflammatory CHEMOKINES; CYTOKINES, and expression of cell activation markers and is a critical regulator of SEPTIC SHOCK.
- DUI
- D000073871 MeSH Browser
- CUI
- M000624135
- Previous indexing
- Membrane Glycoproteins (2000-2017); Receptors, Immunologic (2000-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
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- CL
- classification 0
- DF
- deficiency 0
- DE
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- GE
- genetics 1
- HI
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- IP
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- ME
- metabolism 2
- PH
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- RE
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- TU
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- UL
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