Zinc Finger E-box Binding Homeobox 2 [transkripční faktor Zeb2]
- Terms
-
Smad-Interacting Protein 1
Zeb2 Transcription Factor
Zinc Finger E-box Binding Homeobox 2 Protein
A transcription factor that consists of 8 CYS2-HIS2 ZINC FINGERS flanking a central HOMEOBOX. It binds to the 5'-CACCT-3' DNA sequence located within E-BOX ELEMENTS of many genes essential for embryonic growth and development and regulates their activity; it represses transcription of the E-CADHERIN gene. Mutations in the ZEB2 gene are associated with MOWAT-WILSON SYNDROME.
- DUI
- D000074165 MeSH Browser
- CUI
- M000625738
- Previous indexing
- Homeodomain Proteins (2004-2017); Repressor Proteins (2004-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects 1
- EC
- economics
- GE
- genetics 1
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
ZEB2 protein, human Chemical MeSH Browser
ZEB2 protein, mouse Chemical MeSH Browser
Zeb2 protein, rat Chemical MeSH Browser