Valosin Containing Protein [protein obsahující valosin]

topical
3
Terms

protein CDC48

 

CDC48 Protein
Cell Cycle Protein CDC48
Cell Cycle Protein CDC48p
p97 Valosin-Containing Protein
Valosin-Containing Protein
Valosine-Containing Protein

Persistent link   https://www.medvik.cz/link/D000074405
Definition

A highly-conserved AAA ATPase that functions in the biogenesis of the transitional ENDOPLASMIC RETICULUM and fragmentation and reassembly of the GOLGI APPARATUS during MITOSIS. It also functions in a complex with UFD1L and NPLOC4 proteins to export misfolded ubiquitinated proteins from the endoplasmic reticulum and outer mitochondrial membrane to the cytoplasm for degradation by the PROTEASOME and also plays a role in AUTOPHAGY of ubiquitinated proteins. It occurs in neuronal INCLUSION BODIES from patients with AMYOTROPHIC LATERAL SCLEROSIS and LEWY BODIES from PARKINSON DISEASE patients.

DUI
D000074405 MeSH Browser
CUI
M000626473
History note
2018 (1991)
Public note
2018; VALOSIN CONTAINING PROTEIN was indexed under ADENOSINE TRIPHOSPHATASES and CELL CYCLE PROTEINS 1991-2017

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics 1
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 2
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 554
D08.811.277 Hydrolases 475
D08.811.277.040 Acid Anhydride Hydrolases 6
D08.811.277.040.013 AAA Proteins
D08.811.277.040.013.500 ATPases Associated with Diverse Cellular Activities 8
D08.811.277.040.013.500.032 ATP-Dependent Proteases 7
D08.811.277.040.013.500.063 Dyneins 12
D08.811.277.040.013.500.250 Katanin 2
D08.811.277.040.013.500.375 N-Ethylmaleimide-Sensitive Proteins
D08.811.277.040.013.500.438 Replication Protein C 3
D08.811.277.040.013.500.500 Spastin 1
D08.811.277.040.013.500.750 Valosin Containing Protein 3
D08.811.277.040.025 Adenosine Triphosphatases 429
D08.811.277.040.025.024 ATPases Associated with Diverse Cellular Activities 8
D08.811.277.040.025.024.032 ATP-Dependent Proteases 7
D08.811.277.040.025.024.063 Dyneins 12
D08.811.277.040.025.024.250 Katanin 2
D08.811.277.040.025.024.375 N-Ethylmaleimide-Sensitive Proteins
D08.811.277.040.025.024.438 Replication Protein C 3
D08.811.277.040.025.024.500 Spastin 1
D08.811.277.040.025.024.750 Valosin Containing Protein 3
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 584
D12.776.157 Carrier Proteins 547
D12.776.157.025 AAA Proteins
D12.776.157.025.750 ATPases Associated with Diverse Cellular Activities 8
D12.776.157.025.750.032 ATP-Dependent Proteases 7
D12.776.157.025.750.063 Dyneins 12
D12.776.157.025.750.250 Katanin 2
D12.776.157.025.750.375 N-Ethylmaleimide-Sensitive Proteins
D12.776.157.025.750.438 Replication Protein C 3
D12.776.157.025.750.500 Spastin 1
D12.776.157.025.750.750 Valosin Containing Protein 3
D12.776.167 Cell Cycle Proteins 332
D12.776.167.024 Anaphase-Promoting Complex-Cyclosome 12
D12.776.167.049 Aurora Kinases 4
D12.776.167.100 cdc25 Phosphatases 28
D12.776.167.150 Cellular Apoptosis Susceptibility Protein 4
D12.776.167.163 Cohesins
D12.776.167.175 Cullin Proteins 8
D12.776.167.187 Cyclin-Dependent Kinase Inhibitor Proteins 45
D12.776.167.200 Cyclin-Dependent Kinases 233
D12.776.167.218 Cyclins 112
D12.776.167.242 F-Box-WD Repeat-Containing Protein 7 3
D12.776.167.254 GADD45 Proteins
D12.776.167.265 Geminin 1
D12.776.167.313 Mad2 Proteins 1
D12.776.167.409 Minichromosome Maintenance Proteins 4
D12.776.167.457 NIMA-Related Kinases 4
D12.776.167.469 Polo-like Kinases
D12.776.167.481 S100 Calcium Binding Protein A6 2
D12.776.167.504 Securin 1
D12.776.167.552 Separase 1
D12.776.167.564 Structural Maintenance of Chromosome Protein 1
D12.776.167.576 Survivin 6
D12.776.167.600 Tumor Suppressor Protein p14ARF 4
D12.776.167.800 Valosin Containing Protein 3

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