Eplerenone [eplerenon]

topical
22
Terms

Inspra

 

9,11-Epoxy-7-(methoxycarbonyl)-3-oxo-17-pregn-4-ene-21,17-carbolactone
Eplerenon
Inspra

Definition

A spironolactone derivative and selective ALDOSTERONE RECEPTOR antagonist that is used in the management of HYPERTENSION and CONGESTIVE HEART FAILURE, post-MYOCARDIAL INFARCTION.

DUI
D000077545 MeSH Browser
CUI
M0371594
CAS
Spiro(cyclopenta(7,8)phenanthro(4b,5-b)oxirene-7(3H),2'(3'H)-furan)-10-carboxylic acid, 2,4,4',4a,5',5a,6,6a,8,9,9a,9b,10,11-tetradecahydro-4a,6a-dimethyl-2,5'-dioxo-, methyl ester, (4aS,4bR,5aR,6aS,7 R,9aS,9bR,10R)-
History note
2019 (2000)
Public note
2019; EPLERENONE was indexed under SPIRONOLACTONE/analogs&derivatives 2000-2018

D Chemicals and Drugs
D02.540 Lactones 204
D02.540.150 4-Butyrolactone 26
D02.540.232 Acyl-Butyrolactones 6
D02.540.383 Eplerenone 22
D02.540.505 Macrolides 350
D02.540.529 Orlistat 78
D02.540.552 Picrotoxin 26
D02.540.576 Polyketides 12
D02.540.600 Propiolactone 2
D02.540.679 Spironolactone 274
D02.540.800 Venturicidins
D02.540.950 Zearalenone 18
D04.210.500 Steroids 840
D04.210.500.745 Pregnanes 40
D04.210.500.745.745 Pregnenes 4
D04.210.500.745.745.183 Cortisone 191
D04.210.500.745.745.279 Dimethisterone
D04.210.500.745.745.329 Eplerenone 22
D04.210.500.745.745.379 Ethisterone 4
D04.210.500.745.745.654 Pregnenediones 20
D04.210.500.745.745.725 Pregnenolone 49
D04.210.500.745.745.855 Spironolactone 274