Tumor Protein, Translationally-Controlled 1 [translačně kontrolovaný nádorový protein 1]

topical
Terms

faktor uvolňující histamin
protein P23, Ehrlichův ascitický nádor
protein TPT1

 

Histamine Releasing Factor
Histamine Releasing Factor, Lymphocyte-Dependent
Histamine-Releasing Factor (IgE-Dependent)
Protein P23, Ehrlich Ascites Tumor
TPT1 Protein
Translationally-Controlled Tumor Protein

Definition

A highly expressed protein in tumor cells, encoded by Tpt1 gene. It's involved in various cellular activities including protein synthesis, calcium-binding, MICROTUBULE stabilization, growth, and cell survival. Also, Tpt1 identified as a direct target gene of P53 tumor suppression.

DUI
D000090324 MeSH Browser
CUI
M0132475
History note
2022 (1985)
Public note
2022; TUMOR PROTEIN, TRANSLATIONALLY-CONTROLLED 1 was indexed under BIOMARKERS, TUMOR 1987-2021; under CALCIUM-BINDING PROTEINS 1997-2002; under GROWTH SUBSTANCES 1995-2002; under LYMPHOKINES 1985-2002; and under NEOPLASM PROTEINS 1994-2002

D Chemicals and Drugs
D12.644 Peptides 1 380
D12.644.360.087 Calcineurin 76
D12.644.360.262 Cyclins 112
D12.644.360.365 I-kappa B Proteins 5
D12.644.360.410 Mesothelin 2
D12.644.360.534 Mucin-4 5
D12.644.360.539 NLR Proteins 4
D12.644.360.650 RNA-Binding Protein EWS 15
D12.776 Proteins 2 575
D12.776.476.050 Adenylyl Cyclases 160
D12.776.476.081 Axin Signaling Complex 1
D12.776.476.262 Cyclins 112
D12.776.476.338 GTP-Binding Proteins 117
D12.776.476.350 Guanylate Cyclase 29
D12.776.476.381 I-kappa B Proteins 5
D12.776.476.410 Mesothelin 2
D12.776.476.534 Mucin-4 5
D12.776.476.568 Protein-Tyrosine Kinases 620
D12.776.476.590 PTEN Phosphohydrolase 49
D12.776.476.650 RNA-Binding Protein EWS 15
D12.776.476.900 Sirtuins 20
D12.776.624 Neoplasm Proteins 411
D12.776.624.553 Myeloma Proteins 39
D12.776.624.664 Oncogene Proteins 125
D12.776.624.776 Tumor Suppressor Proteins 265