5-Aminolevulinate Synthetase [5-aminolevulátsynthetasa]
- Terms
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5-ALA syntetáza
5-aminolevulát syntáza
5-aminolevulát syntetáza
5-aminolevulát synthetasa
5-aminolevulátsyntetáza
syntetáza kyseliny aminolevulové
synthetasa kyseliny aminolevulové
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5-Aminolevulinate Synthase
Aminolevulinic Acid Synthetase
delta-Aminolevulinate Synthase
delta-Aminolevulinic Acid Synthetase
An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis. In liver feedback is inhibited by heme. EC 2.3.1.37.
- DUI
- D000624 MeSH Browser
- CUI
- M0000954
- CAS
- Succinyl-CoA:glycine C-Succinyltransferase (decarboxylating)
- Previous indexing
- Acyltransferases (1966-1971)
- History note
- 98(72)
- Public note
- 98; see AMINOLEVULINIC ACID SYNTHETASE 1972-97
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