beta-N-Acetylhexosaminidases [beta-N-acetylhexosaminidasy]
- Terms
-
beta-hexosaminidasa
beta-hexosaminidáza
beta-hexózaminidáza
beta-N-acetylhexosaminidasa
beta-N-acetylhexosaminidáza
beta-N-acetylhexosaminidázy
beta-N-acetylhexózaminidázy
-
beta-Hexosaminidase
beta-N-Acetyl-D-hexosaminidase
beta-N-Acetyl-hexosaminidase
beta-N-Acetylhexosaminidase
N-Acetyl-beta-D-hexosaminidase
A hexosaminidase specific for non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. It acts on GLUCOSIDES; GALACTOSIDES; and several OLIGOSACCHARIDES. Two specific mammalian isoenzymes of beta-N-acetylhexoaminidase are referred to as HEXOSAMINIDASE A and HEXOSAMINIDASE B. Deficiency of the type A isoenzyme causes TAY-SACHS DISEASE, while deficiency of both A and B isozymes causes SANDHOFF DISEASE. The enzyme has also been used as a tumor marker to distinguish between malignant and benign disease.
- Annotation
- do not confuse with ACETYLGLUCOSAMINIDASE; /defic: consider also TAY SACHS DISEASE and SANDHOFF DISEASE
- DUI
- D001619 MeSH Browser
- CUI
- M0002423
- CAS
- beta-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase
- Previous indexing
- Glycoside Hydrolases (1966-1970); Hexosaminidases (1971-1986)
- History note
- 2008(1988)
- Public note
- 2008; see BETA-N-ACETYL-D-HEXOSAMINIDASE 1988-2007
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 6
- BI
- biosynthesis 0
- BL
- blood 1
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 15
- CL
- classification 0
- DF
- deficiency 1
- DE
- drug effects 1
- EC
- economics 0
- GE
- genetics 9
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 8
- ME
- metabolism 22
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 1
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0