Complement C5 [komplement C5]
topical
26
- Terms
-
komplement 5
komplement C5 - prekursor
Pro-C5
-
C5 Complement
Complement 5
Complement C5, Precursor
Complement Component 5
Precursor C5
Pro-C5
Pro-complement 5
Persistent link
https://www.medvik.cz/link/D003182
Definition
C5 plays a central role in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. C5 is cleaved by C5 CONVERTASE into COMPLEMENT C5A and COMPLEMENT C5B. The smaller fragment C5a is an ANAPHYLATOXIN and mediator of inflammatory process. The major fragment C5b binds to the membrane initiating the spontaneous assembly of the late complement components, C5-C9, into the MEMBRANE ATTACK COMPLEX.
- DUI
- D003182 MeSH Browser
- CUI
- M0004937
- Previous indexing
- Complement (1968-1974); Histamine Liberation (1966-1974)
- History note
- 2006 (1975)
- Public note
- 2006; see COMPLEMENT 5 1978-2005, see COMPLEMENT 1975-1977; COMPLEMENT C5, PRECURSOR was indexed under COMPLEMENT 5 1991-2005
Allowable subheadings
- AD
- administration & dosage 2
- AE
- adverse effects 0
- AG
- agonists 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 17
- BI
- biosynthesis 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 4
- EC
- economics 0
- GE
- genetics 1
- HI
- history 0
- IM
- immunology 3
- IP
- isolation & purification 1
- ME
- metabolism 0
- PK
- pharmacokinetics 0
- PD
- pharmacology 1
- PH
- physiology 1
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 2
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs
D12.776.124.486.274.450.625
Complement C5b
D12.776.124.486.274.550
Complement C6
D12.776.124.486.274.650
Complement C7
D12.776.124.486.274.850
Complement C9