Phenobarbital [fenobarbital]
topical
199
- Terms
-
Gardenal
Hysteps
Luminal
phenobarbitalum natricum
sodná sůl fenobarbitalu
-
Gardenal
Hysteps
Luminal
Phenemal
Phenobarbital Sodium
Phenobarbital, Monosodium Salt
Phenobarbitone
Phenylbarbital
Phenylethylbarbituric Acid
Persistent link
https://www.medvik.cz/link/D010634
Definition
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
- DUI
- D010634 MeSH Browser
- CUI
- M0016514
- CAS
- 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-phenyl-
Allowable subheadings
- AD
- administration & dosage 37
- AE
- adverse effects 20
- AG
- agonists 0
- AA
- analogs & derivatives 4
- AN
- analysis 7
- AI
- antagonists & inhibitors 0
- BL
- blood 7
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 2
- CL
- classification 0
- EC
- economics 0
- HI
- history 0
- IM
- immunology 1
- IP
- isolation & purification 3
- ME
- metabolism 10
- PK
- pharmacokinetics 12
- PD
- pharmacology 41
- PO
- poisoning 2
- RE
- radiation effects 0
- ST
- standards 1
- SD
- supply & distribution 0
- TU
- therapeutic use 38
- TO
- toxicity 6
- UR
- urine 2
...
Occurrences in Medvik records