Receptor, Insulin [receptor inzulinu]

topical
69
Terms

inzulinový receptor, podjednotka alfa
inzulinový receptor, podjednotka beta
receptor insulinu

 

Insulin Receptor
Insulin Receptor alpha Chain
Insulin Receptor alpha Subunit
Insulin Receptor beta Chain
Insulin Receptor beta Subunit
Insulin Receptor Protein-Tyrosine Kinase
Insulin-Dependent Tyrosine Protein Kinase
Receptors, Insulin

Persistent link   https://www.medvik.cz/link/D011972
Definition

A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE.

DUI
D011972 MeSH Browser
CUI
M0018605
Previous indexing
Receptors, Drug (1968-1976); Receptors, Endogenous Substances (1973-1976); Insulin (1966-1976)
History note
2000(1977); for INSULIN RECEPTOR PROTEIN-TYROSINE KINASE use RECEPTOR, INSULIN (NM) 1983-1993
Public note
2000; for INSULIN RECEPTOR PROTEIN-TYROSINE KINASE see INSULIN RECEPTOR PROTEIN-TYROSINE KINASE 1994-1999; INSULIN-DEPENDENT PROTEIN TYROSINE KINASE was indexed under PROTEIN-TYROSINE KINASE 1986-1993 & PROTEIN KINASES 1983-1985

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis 2
AI
antagonists & inhibitors 1
BI
biosynthesis
BL
blood 2
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 13
CL
classification 1
DF
deficiency 2
DE
drug effects 8
EC
economics
GE
genetics 14
HI
history
IM
immunology 1
IP
isolation & purification
ME
metabolism 26
PK
pharmacokinetics
PD
pharmacology 1
PH
physiology 11
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure 1
UR
urine

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 551
D08.811.913 Transferases 72
D08.811.913.696 Phosphotransferases 69
D08.811.913.696.620 Phosphotransferases (Alcohol Group Acceptor) 32
D08.811.913.696.620.682 Protein Kinases 249
D08.811.913.696.620.682.725 Protein-Tyrosine Kinases 622
D08.811.913.696.620.682.725.400 Receptor Protein-Tyrosine Kinases 154
D08.811.913.696.620.682.725.400.002 Anaplastic Lymphoma Kinase 87
D08.811.913.696.620.682.725.400.003 c-Mer Tyrosine Kinase 2
D08.811.913.696.620.682.725.400.005 Discoidin Domain Receptors
D08.811.913.696.620.682.725.400.009 ErbB Receptors 800
D08.811.913.696.620.682.725.400.020 fms-Like Tyrosine Kinase 3 53
D08.811.913.696.620.682.725.400.050 Proto-Oncogene Proteins c-kit 77
D08.811.913.696.620.682.725.400.075 Proto-Oncogene Proteins c-met 30
D08.811.913.696.620.682.725.400.087 Proto-Oncogene Proteins c-ret 42
D08.811.913.696.620.682.725.400.093 Receptor Tyrosine Kinase-like Orphan Receptors 9
D08.811.913.696.620.682.725.400.177 Receptor, Fibroblast Growth Factor, Type 1 11
D08.811.913.696.620.682.725.400.178 Receptor, Fibroblast Growth Factor, Type 2 3
D08.811.913.696.620.682.725.400.179 Receptor, Fibroblast Growth Factor, Type 3 28
D08.811.913.696.620.682.725.400.180 Receptor, Fibroblast Growth Factor, Type 4 3
D08.811.913.696.620.682.725.400.185 Receptor, IGF Type 1 43
D08.811.913.696.620.682.725.400.200 Receptor, Insulin 69
D08.811.913.696.620.682.725.400.500 Receptor, Macrophage Colony-Stimulating Factor 1
D08.811.913.696.620.682.725.400.660 Receptor, trkA 15
D08.811.913.696.620.682.725.400.700 Receptor, trkB 8
D08.811.913.696.620.682.725.400.800 Receptor, trkC 16
D08.811.913.696.620.682.725.400.850 Receptors, Eph Family 1
D08.811.913.696.620.682.725.400.900 Receptors, Platelet-Derived Growth Factor 33
D08.811.913.696.620.682.725.400.925 Receptors, TIE 5
D08.811.913.696.620.682.725.400.950 Receptors, Vascular Endothelial Growth Factor 350
D08.811.913.696.620.682.725.400.975 Axl Receptor Tyrosine Kinase
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 581
D12.776.476 Intracellular Signaling Peptides and Proteins 175
D12.776.476.568 Protein-Tyrosine Kinases 622
D12.776.476.568.400 Receptor Protein-Tyrosine Kinases 154
D12.776.476.568.400.002 Anaplastic Lymphoma Kinase 87
D12.776.476.568.400.003 c-Mer Tyrosine Kinase 2
D12.776.476.568.400.005 Discoidin Domain Receptors
D12.776.476.568.400.009 ErbB Receptors 800
D12.776.476.568.400.020 fms-Like Tyrosine Kinase 3 53
D12.776.476.568.400.050 Proto-Oncogene Proteins c-kit 77
D12.776.476.568.400.075 Proto-Oncogene Proteins c-met 30
D12.776.476.568.400.087 Proto-Oncogene Proteins c-ret 42
D12.776.476.568.400.093 Receptor Tyrosine Kinase-like Orphan Receptors 9
D12.776.476.568.400.177 Receptor, Fibroblast Growth Factor, Type 1 11
D12.776.476.568.400.178 Receptor, Fibroblast Growth Factor, Type 2 3
D12.776.476.568.400.179 Receptor, Fibroblast Growth Factor, Type 3 28
D12.776.476.568.400.180 Receptor, Fibroblast Growth Factor, Type 4 3
D12.776.476.568.400.185 Receptor, IGF Type 1 43
D12.776.476.568.400.200 Receptor, Insulin 69
D12.776.476.568.400.500 Receptor, Macrophage Colony-Stimulating Factor 1
D12.776.476.568.400.660 Receptor, trkA 15
D12.776.476.568.400.700 Receptor, trkB 8
D12.776.476.568.400.800 Receptor, trkC 16
D12.776.476.568.400.850 Receptors, Eph Family 1
D12.776.476.568.400.900 Receptors, Platelet-Derived Growth Factor 33
D12.776.476.568.400.925 Receptors, TIE 5
D12.776.476.568.400.950 Receptors, Vascular Endothelial Growth Factor 350
D12.776.476.568.400.975 Axl Receptor Tyrosine Kinase
D12.776.543 Membrane Proteins 850
D12.776.543.750 Receptors, Cell Surface 511
D12.776.543.750.630 Receptor Protein-Tyrosine Kinases 154
D12.776.543.750.630.002 Anaplastic Lymphoma Kinase 87
D12.776.543.750.630.003 c-Mer Tyrosine Kinase 2
D12.776.543.750.630.005 Discoidin Domain Receptors
D12.776.543.750.630.009 ErbB Receptors 800
D12.776.543.750.630.020 fms-Like Tyrosine Kinase 3 53
D12.776.543.750.630.124 Proto-Oncogene Proteins c-kit 77
D12.776.543.750.630.186 Proto-Oncogene Proteins c-met 30
D12.776.543.750.630.217 Proto-Oncogene Proteins c-ret 42
D12.776.543.750.630.233 Receptor Tyrosine Kinase-like Orphan Receptors 9
D12.776.543.750.630.440 Receptor, Fibroblast Growth Factor, Type 1 11
D12.776.543.750.630.441 Receptor, Fibroblast Growth Factor, Type 2 3
D12.776.543.750.630.442 Receptor, Fibroblast Growth Factor, Type 3 28
D12.776.543.750.630.443 Receptor, Fibroblast Growth Factor, Type 4 3
D12.776.543.750.630.468 Receptor, IGF Type 1 43
D12.776.543.750.630.484 Receptor, Insulin 69
D12.776.543.750.630.492 Receptor, Macrophage Colony-Stimulating Factor 1
D12.776.543.750.630.496 Receptor, trkA 15
D12.776.543.750.630.498 Receptor, trkB 8
D12.776.543.750.630.499 Receptor, trkC 16
D12.776.543.750.630.500 Receptors, Eph Family 1
D12.776.543.750.630.625 Receptors, Platelet-Derived Growth Factor 33
D12.776.543.750.630.687 Receptors, TIE 5
D12.776.543.750.630.750 Receptors, Vascular Endothelial Growth Factor 350
D12.776.543.750.630.875 Axl Receptor Tyrosine Kinase
D12.776.543.750.750 Receptors, Peptide 22
D12.776.543.750.750.580 Receptors, Pancreatic Hormone 2
D12.776.543.750.750.580.300 Receptor, Insulin 69
D12.776.543.750.750.580.350 Receptors, Glucagon 26
D12.776.543.750.750.580.720 Receptors, Somatostatin 71

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