Retinaldehyde [retinaldehyd]
- Terms
-
11-cis-retinal
11-trans-retinal
all-trans-retinal
axeroftal
retinal
retinal izomeráza
retinen
-
11-cis-Retinal
11-trans-Retinal
3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-Nonatetraenal
all-trans-Retinal
Axerophthal
Retinal
Retinene
Retinyl Aldehydde
Vitamin A Aldehyde
A diterpene derived from the carotenoid VITAMIN A which functions as the active component of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation straightens-out the bend of the retinal molecule and causes a change in the shape of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed reactions convert the 11-trans-retinal back to the cis-isomer.
- Annotation
- /biosyn /physiol permitted
- podhesla /biosyntéza /fyziologie
- DUI
- D012172 MeSH Browser
- CUI
- M0018957
- History note
- 91(75); was see under RETINOIDS 1984-90; was see under VITAMIN A 1968-83
- Online note
- search VITAMIN A 1968-74
- Public note
- 91; was see under RETINOIDS 1984-90; was see under VITAMIN A 1968-83
Allowable subheadings
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- administration & dosage 1
- AE
- adverse effects 1
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- biosynthesis
- BL
- blood
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- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- DF
- deficiency
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 2
- PK
- pharmacokinetics
- PD
- pharmacology
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- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 1
- TO
- toxicity
- UR
- urine
13-cis-retinal Chemical MeSH Browser
9-cis-retinal Chemical MeSH Browser
diacneal Chemical MeSH Browser