Factor VIIIa [faktor VIIIa]
topical
14
- Terms
-
faktor VIII aktivovaný
koagulační faktor VIIIa
-
Blood Coagulation Factor VIII, Activated
Coagulation Factor VIIIa
Factor 8A
Factor Eight A
Factor VIII, Activated
Factor VIII, Thrombin-Activated
Factor VIIIa Heavy Chain, 200 kDa Isoform
Factor VIIIa Heavy Chain, 92 kDa Isoform
Factor VIIIa Light Chain
Persistent link
https://www.medvik.cz/link/D015944
Definition
Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably calcium) complex and functions as a cofactor in the enzymatic activation of factor X by factor IXa. Factor VIIIa is similar in structure and generation to factor Va.
- DUI
- D015944 MeSH Browser
- CUI
- M0024392
- CAS
- Blood-coagulation factor VIIIa, procoagulant
- Previous indexing
- Factor VIII (1981-1989)
- History note
- 90
- Public note
- 90
Combination
- deficiency
- Hemophilia A
Allowable subheadings
- AD
- administration & dosage 6
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis 1
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DE
- drug effects
- EC
- economics
- GE
- genetics 2
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology 4
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 3
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs