Mutagenesis, Insertional [inzerční mutageneze]
- Terms
-
genová inzerce
inzerce genu
inzerce sekvence
inzerční aktivace
inzerční mutace
inzerční mutageneze pomocí linkerů
kazetová mutageneze
mutageneze inzerční
sekvenční inzerce
virová inzerční mutageneze
-
Gene Insertion
Insertion Mutation
Insertional Activation
Insertional Mutagenesis
Linker-Insertion Mutagenesis
Mutagenesis, Cassette
Sequence Insertion
Viral Insertional Mutagenesis
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.
- DUI
- D016254 MeSH Browser
- CUI
- M0024827
- Previous indexing
- DNA Insertion Elements (1983-1990); Mutation (1982-1990)
- History note
- 91
- Public note
- 91
Allowable subheadings
- DE
- drug effects
- EC
- economics
- GE
- genetics 7
- HI
- history
- IM
- immunology
- IS
- instrumentation
- MT
- methods 3
- PH
- physiology 1
- RE
- radiation effects
- ST
- standards
- SN
- statistics & numerical data 1