Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.

DUI

D018079 MeSH Browser

CUI

M0027273

Previous indexing

GABA (1979-1984); Receptors, Cell Surface (1973-1984); Receptors, GABA-A (1985-1993)

History note

94; GABA RECEPTORS & RECEPTORS, GAMMA-AMINOBUTYRIC ACID were see RECEPTORS, GABA-BENZODIAZEPINE 1985-93

Online note

use RECEPTORS, GABA-A to search GABA RECEPTORS & RECEPTORS, GAMMA-AMINOBUTYRIC ACID 1985-93

Public note

94; GABA RECEPTORS & RECEPTORS, GAMMA-AMINOBUTYRIC ACID were see RECEPTORS, GABA-BENZODIAZEPINE 1985-93