Trinucleotide Repeat Expansion [expanze trinukleotidových repetic]

topical
42
Terms

expandované trinukleotidové repetice
expanze trinukleotidových repetitivních sekvencí

 

Expanded Trinucleotide Repeat

Persistent link   https://www.medvik.cz/link/D019680
Definition

An increased number of contiguous trinucleotide repeats in the DNA sequence from one generation to the next. The presence of these regions is associated with diseases such as FRAGILE X SYNDROME and MYOTONIC DYSTROPHY. Some CHROMOSOME FRAGILE SITES are composed of sequences where trinucleotide repeat expansion occurs.

DUI
D019680 MeSH Browser
CUI
M0029211
Previous indexing
Repetitive Sequences, Nucleic Acid (1981-1997)
History note
99(98)
Public note
99; see DNA SEQUENCE, UNSTABLE 1998

Allowable subheadings

DE
drug effects 0
ES
ethics 0
GE
genetics 17
IM
immunology 0
PH
physiology 0
RE
radiation effects 0

G Phenomena and Processes
G02 Chemical Phenomena 307
G02.111 Biochemical Phenomena 370
G02.111.570 Molecular Structure 1 314
G02.111.570.080 Base Sequence 999
G02.111.570.080.708 Repetitive Sequences, Nucleic Acid 123
G02.111.570.080.708.800 Tandem Repeat Sequences 53
G02.111.570.080.708.800.140 DNA Repeat Expansion 7
G02.111.570.080.708.800.140.865 Trinucleotide Repeat Expansion 42
G02.111.570.080.708.800.500 Microsatellite Repeats 241
G02.111.570.080.708.800.500.850 Trinucleotide Repeats 42
G02.111.570.080.708.800.500.850.200 Trinucleotide Repeat Expansion 42
G05 Genetic Phenomena 135
G05.360 Genetic Structures 25
G05.360.080 Base Sequence 999
G05.360.080.708 Repetitive Sequences, Nucleic Acid 123
G05.360.080.708.800 Tandem Repeat Sequences 53
G05.360.080.708.800.074 DNA Repeat Expansion 7
G05.360.080.708.800.074.865 Trinucleotide Repeat Expansion 42
G05.360.080.708.800.500 Microsatellite Repeats 241
G05.360.080.708.800.500.850 Trinucleotide Repeats 42
G05.360.080.708.800.500.850.200 Trinucleotide Repeat Expansion 42
G05.360.340 Genome 361
G05.360.340.024 Genome Components 13
G05.360.340.024.189 DNA Sequence, Unstable 4
G05.360.340.024.189.220 DNA Repeat Expansion 7
G05.360.340.024.189.220.865 Trinucleotide Repeat Expansion 42
G05.360.340.024.850 Tandem Repeat Sequences 53
G05.360.340.024.850.500 Microsatellite Repeats 241
G05.360.340.024.850.500.850 Trinucleotide Repeats 42
G05.360.340.024.850.500.850.200 Trinucleotide Repeat Expansion 42
G05.365 Genetic Variation 858
G05.365.590 Mutation 4 993
G05.365.590.220 DNA Repeat Expansion 7
G05.365.590.220.865 Trinucleotide Repeat Expansion 42
G05.558 Mutagenesis 276
G05.558.220 DNA Repeat Expansion 7
G05.558.220.865 Trinucleotide Repeat Expansion 42

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