Caspase 1 [kaspasa 1]
topical
16
- Terms
-
enzym IL1BC
enzym konvertující interleukin-1 beta
kaspáza 1
konvertáza IL-1 beta
prekurzor kaspázy 1
prokaspasa 1
prokaspáza 1
proteasa ICE
proteáza ICE
-
CASP1 Caspase
ICE Protease
IL-1 beta Convertase
IL-1 beta-Converting Enzyme
IL1BC Enzyme
Interleukin-1 Converting Enzyme
Interleukin-1beta Converting Enzyme
Pro-Caspase-1
Procaspase-1
Persistent link
https://www.medvik.cz/link/D020170
Definition
A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays a role in INFLAMMATION by catalytically converting the inactive forms of CYTOKINES such as interleukin-1beta to their active, secreted form. Caspase 1 is referred as interleukin-1beta converting enzyme and is frequently abbreviated ICE.
- DUI
- D020170 MeSH Browser
- CUI
- M0029892
- Previous indexing
- Cysteine Proteinases (1995-1998); Metalloproteinases (1989-1994)
- History note
- 1999; use CASPASE 1 (NM) 1989-1998
- Public note
- 1999; INTERLEUKIN 1BETA CONVERTING ENZYME (now CASPASE 1) was indexed under CYSTEINE PROTEINASES 1995-1998 & METALLOPROTEINASES 1989-1994
Combination
- antagonists & inhibitors
- Caspase Inhibitors
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AN
- analysis 1
- BI
- biosynthesis 1
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 3
- HI
- history 0
- IM
- immunology 1
- IP
- isolation & purification 1
- ME
- metabolism 6
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 3
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs