DNA-binding domains present in proteins of the HMG-box superfamily including the archetypal HMGB PROTEINS, a number of sequence specific TRANSCRIPTION FACTORS, and other DNA-BINDING PROTEINS. The domains consist of 70-80 amino acids that form an L-shaped fold from three alpha-helical segments. The domain has the capacity to recognize and/or induce specific DNA structures and effect the accessibility of the DNA to other proteins involved in transcription, recombination, or DNA repair. (Note that not all HIGH MOBILITY GROUP PROTEINS contain this domain.)

Annotation

HIGH MOBILITY GROUP PROTEINS is also available

DUI

D024742 MeSH Browser

CUI

M0371731

Previous indexing

High Mobility Group Proteins (1991-2001)

History note

2002

Public note

2002